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Cdh15 Gene Detail
Summary
  • Symbol
    Cdh15
  • Name
    cadherin 15
  • Synonyms
    Cdh14, Mcad, M cadherin
  • Feature Type
    protein coding gene
  • IDs
    MGI:106672
    NCBI Gene: 12555
  • Gene Overview
    MyGene.info: CDH15
Location & Maps
more
  • Sequence Map
    Chr8:122848374-122867397 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      19024 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 71.99 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    CDH15, cadherin 15
  • Vertebrate Orthologs
    8
  • Human Ortholog
    CDH15, cadherin 15
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CDH14, CDH3, CDHM, MCAD, MRD3
  • Links
    NCBI Gene ID: 1013
    neXtProt AC: NX_P55291

  • Chr Location
    16q24.3; chr16:89171755-89195492 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human CDH15 associations

Human Disease Mouse Models
       Mental Retardation, Autosomal Dominant 3; MRD3   OMIM: 612580
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype reference
Homozygous null mice are viable, fertile, and show no apparent defects in the development, maintenance, or regeneration of skeletal muscle or in the cerebellum.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 12555 NCBI Gene Model | MGI Sequence Detail 19024 C57BL/6J ±  kb
transcript NM_007662 RefSeq | MGI Sequence Detail 2843 Not Specified  
polypeptide P33146 UniProt | EBI | MGI Sequence Detail 784 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    216 from dbSNP Build 142
  • RFLP
Protein
Information
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Molecular
Reagents
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  • All nucleic 24
    cDNA 20
    Primer pair 2
    Other 2

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-16328, MGD-MRK-19362, MGD-MRK-35131, MGI:2142505, MGI:99550
References
more
  • Summaries
    All 51
    Developmental Gene Expression 21
    Gene Ontology 6
    Phenotypes 1
  • Earliest
    J:11403 Hatta M, et al., Genomic organization and chromosomal mapping of the mouse P-cadherin gene. Nucleic Acids Res. 1991 Aug 25;19(16):4437-41
  • Latest
    J:200444 Millay DP, et al., Myomaker is a membrane activator of myoblast fusion and muscle formation. Nature. 2013 Jul 18;499(7458):301-5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory