|Human Homolog||CDKN1A, cyclin-dependent kinase inhibitor 1A (p21, Cip1)|
|NCBI Gene ID||1026|
|Human Synonyms||CAP20, CDKN1, CIP1, MDA-6, P21, p21CIP1, SDI1, WAF1|
|Human Chr (Location)||6p21.2; chr6:36676460-36687339 (+) GRCh38|
Homozygotes for knock-out alleles exhibit increased spontaneous tumorigenesis, altered resistance to induced tumors, abnormal immune system morphology and physiology, delayed cellular senescence, abnormal response to xenobiotics and injury, and autoimmunity.
|Process||cell cycle, cell cycle arrest, ...|
|Component||cyclin-dependent protein kinase holoenzyme complex, cytoplasm, ...|
|Function||cyclin binding, cyclin-dependent protein kinase activating kinase activity, ...|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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