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Rai1
Gene Detail
Symbol

Name
ID
Rai1
retinoic acid induced 1
MGI:103291
Synonyms
Gt1
Feature Type
protein coding gene
Genetic Map
Chromosome 11
37.81 cM, cytoband B2
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr11:60105013-60199197 bp, + strand
From VEGA annotation of GRCm38

  94185 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Gene Tree: Rai1
Mutations,
alleles, and
phenotypes
All mutations/alleles(53) : Gene trapped(47) Targeted(6)
Genomic Mutations involving Rai1 (3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions of this gene usually die as embryos. Survivors have shortened life spans and show severe craniofacial and axial skeleton defects.
 
Human Diseases Modeled Using Mouse Rai1 (1)    Alleles Annotated to Human Diseases(4)   
Interactions
Rai1 interacts with 259 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process circadian regulation of gene expression, negative regulation of multicellular organism growth, ...
Component cytoplasm, nucleus
Function metal ion binding, zinc ion binding
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (119)    Tissues (86)    Images (10)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 55
In situ reporter (knock in) 55
RT-PCR 9
cDNA source data(70)
External Resources: Allen Institute   Expression Atlas
Molecular
reagents
All nucleic(75) Genomic(1) cDNA(70) Primer pair(3) Other(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000005811 (Evidence)
Ensembl Gene ModelENSMUSG00000062115 (Evidence)
Entrez Gene102637597, 19377
UniGene296366
DFCITC1578500
NIA Mouse Gene IndexU012692
Consensus CDS ProjectCCDS24784.1
International Mouse Knockout Project StatusRai1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005811 VEGA Gene Model | MGI Sequence Detail 94185 C57BL/6J ±  kb
transcript OTTMUST00000012881 VEGA | MGI Sequence Detail 6921 Not Applicable 
polypeptide OTTMUSP00000005990 VEGA | MGI Sequence Detail 1889 Not Applicable 

For the selected sequences
All sequences(37) UniProt(7)
Polymorphisms
SNPs within 2kb(404 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001965 Zinc finger, PHD-type
Protein Ontology PR:000013692 retinoic acid-induced protein 1
References
(Earliest) J:26209 Imai Y, et al., Cloning of a retinoic acid-induced gene, GT1, in the embryonal carcinoma cell line P19: neuron-specific expression in the mouse brain. Brain Res Mol Brain Res. 1995 Jul;31(1-2):1-9
(Latest) J:196808 Williams SR, et al., Smith-Magenis syndrome results in disruption of CLOCK gene transcription and reveals an integral role for RAI1 in the maintenance of circadian rhythmicity. Am J Hum Genet. 2012 Jun 8;90(6):941-9
All references(42)
Disease annotation references (3)
Other
accession IDs
MGD-MRK-24173

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory