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Phenotype Images associated with this Transgene
Nomenclature
Symbol: Tg(Col2a1-cre)1Bhr
Name: transgene insertion 1, Richard R Behringer
MGI ID: MGI:2176070
Synonyms: Col2a1-Cre, Col2-Cre
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Impairment of ossification in various conditional Sp7tm1Rnis/Sp7tm1Rnis miceSp7tm1Rnis/Sp7tm1Rnis
Tg(Col11a2-cre)1Ntsu/0		involves: C57BL * C57BL/6 * CBA/JNCrlj * DBA/2
Sp7tm1Rnis/Sp7tm1Rnis
Tg(Col2a1-cre)1Bhr/0		involves: C57BL * C57BL/6 * CBA/JNCrlj * SJL
Sp7tm1Rnis/Sp7tm1Rnis
Tg(Prrx1-cre)1Cjt/0		involves: C57BL * C57BL/6 * CBA/JNCrlj * SJL/J
Inhibited calcification in Sp7tm1Rnis/Sp7tm1Rnis Tg(Col2a1-cre)1Bhr/0 miceSp7tm1Rnis/Sp7tm1Rnis
Tg(Col2a1-cre)1Bhr/0		involves: C57BL * C57BL/6 * CBA/JNCrlj * SJL
Small size, hypomorphic ears and shortened snout in n-TUtca2tm1Dhat/n-TUtca2tm1Dhat Tg(Col2a1-cre)1Bhr/0 micen-TUtca2tm1Dhat/n-TUtca2tm1Dhat
Tg(Col2a1-cre)1Bhr/0		B6.Cg-n-TUtca2tm1Dhat Tg(Col2a1-cre)1Bhr
Compromised skeletal development in n-TUtca2tm1Dhat/n-TUtca2tm1Dhat Tg(Col2a1-cre)1Bhr/0 micen-TUtca2tm1Dhat/n-TUtca2tm1Dhat
Tg(Col2a1-cre)1Bhr/0		B6.Cg-n-TUtca2tm1Dhat Tg(Col2a1-cre)1Bhr
Tibial epiphyseal growth plate abnormalities in n-TUtca2tm1Dhat/n-TUtca2tm1Dhat Tg(Col2a1-cre)1Bhr/0 micen-TUtca2tm1Dhat/n-TUtca2tm1Dhat
Tg(Col2a1-cre)1Bhr/0		B6.Cg-n-TUtca2tm1Dhat Tg(Col2a1-cre)1Bhr
Chondronecrosis in the articular cartilage of n-TUtca2tm1Dhat/n-TUtca2tm1Dhat Tg(Col2a1-cre)1Bhr/0 micen-TUtca2tm1Dhat/n-TUtca2tm1Dhat
Tg(Col2a1-cre)1Bhr/0		B6.Cg-n-TUtca2tm1Dhat Tg(Col2a1-cre)1Bhr
Auricular chondronecrosis and hypoplasia in n-TUtca2tm1Dhat/n-TUtca2tm1Dhat Tg(Col2a1-cre)1Bhr/0 micen-TUtca2tm1Dhat/n-TUtca2tm1Dhat
Tg(Col2a1-cre)1Bhr/0		B6.Cg-n-TUtca2tm1Dhat Tg(Col2a1-cre)1Bhr
Tracheomalacia and airway lumen narrowing in n-TUtca2tm1Dhat/n-TUtca2tm1Dhat Tg(Col2a1-cre)1Bhr/0 micen-TUtca2tm1Dhat/n-TUtca2tm1Dhat
Tg(Col2a1-cre)1Bhr/0		B6.Cg-n-TUtca2tm1Dhat Tg(Col2a1-cre)1Bhr
Severe chondrodysplasia in Mbtps1tm1Jdh/Mbtps1tm1Jdh Tg(Col2a1-cre)1Bhr/0 miceMbtps1tm1Jdh/Mbtps1tm1Jdh
Tg(Col2a1-cre)1Bhr/0		involves: 129S6/SvEvTac * C57BL/6 * SJL
Lack of organized hypertrophy and endochondral bone formation in Mbtps1tm1Jdh/Mbtps1tm1Jdh Tg(Col2a1-cre)1Bhr/0 miceMbtps1tm1Jdh/Mbtps1tm1Jdh
Tg(Col2a1-cre)1Bhr/0		involves: 129S6/SvEvTac * C57BL/6 * SJL
Increased chondrocyte apoptosis and absence of vascular invasion in the skeletal elements of Mbtps1tm1Jdh/Mbtps1tm1Jdh Tg(Col2a1-cre)1Bhr/0 miceMbtps1tm1Jdh/Mbtps1tm1Jdh
Tg(Col2a1-cre)1Bhr/0		involves: 129S6/SvEvTac * C57BL/6 * SJL
Growth defects in Gt(ROSA)26Sortm1(Wnt4)Bhr/Gt(ROSA)26Sor+ Tg(Col2a1-cre)1Bhr/0 miceGt(ROSA)26Sortm1(Wnt4)Bhr/Gt(ROSA)26Sor+
Tg(Col2a1-cre)1Bhr/0		involves: 129S7/SvEvBrd * C57BL/6 * SJL
Skeletal defects in Gt(ROSA)26Sortm1(Wnt4)Bhr/Gt(ROSA)26Sor+ Tg(Col2a1-cre)1Bhr/0 miceGt(ROSA)26Sortm1(Wnt4)Bhr/Gt(ROSA)26Sor+
Tg(Col2a1-cre)1Bhr/0		involves: 129S7/SvEvBrd * C57BL/6 * SJL
Radiographic analysis of 9 month old Gt(ROSA)26Sortm1(Wnt4)Bhr/Gt(ROSA)26Sor+ Tg(Col2a1-cre)1Bhr/0 miceGt(ROSA)26Sortm1(Wnt4)Bhr/Gt(ROSA)26Sor+
Tg(Col2a1-cre)1Bhr/0		involves: 129S7/SvEvBrd * C57BL/6 * SJL
Long bone abnormalities in Gt(ROSA)26Sortm1(Wnt4)Bhr/Gt(ROSA)26Sor+ Tg(Col2a1-cre)1Bhr/0 miceGt(ROSA)26Sortm1(Wnt4)Bhr/Gt(ROSA)26Sor+
Tg(Col2a1-cre)1Bhr/0		involves: 129S7/SvEvBrd * C57BL/6 * SJL
Gt(ROSA)26Sortm1(Wnt4)Bhr/Gt(ROSA)26Sor+ Tg(Col2a1-cre)1Bhr/0 mice exhibit a decrease in cell proliferation in the epiphyseal growth plate of the proximal tibiaGt(ROSA)26Sortm1(Wnt4)Bhr/Gt(ROSA)26Sor+
Tg(Col2a1-cre)1Bhr/0		involves: 129S7/SvEvBrd * C57BL/6 * SJL
Skeletal abnormalities in Bmpr1btm1Kml/Bmpr1btm1Kml, Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr Tg(Col2a1-cre)1Bhr/?, and Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr Bmpr1btm1Kml/Bmpr1btm1Kml Tg(Col2a1-cre)1Bhr/? miceBmpr1btm1Kml/Bmpr1btm1Kmlinvolves: 129S/SvEv
Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr
Bmpr1btm1Kml/Bmpr1btm1Kml
Tg(Col2a1-cre)1Bhr/?		involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * SJL
Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr
Tg(Col2a1-cre)1Bhr/?		involves: 129S7/SvEvBrd * C57BL/6 * SJL
Impaired chondrocyte differentiation in Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr Bmpr1btm1Kml/Bmpr1btm1Kml Tg(Col2a1-cre)1Bhr/? miceBmpr1atm2.1Bhr/Bmpr1atm2.1Bhr
Bmpr1btm1Kml/Bmpr1btm1Kml
Tg(Col2a1-cre)1Bhr/?		involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * SJL
Impaired chondrogenesis and extracellular matrix expression in Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr Bmpr1btm1Kml/Bmpr1btm1Kml Tg(Col2a1-cre)1Bhr/? miceBmpr1atm2.1Bhr/Bmpr1atm2.1Bhr
Bmpr1btm1Kml/Bmpr1btm1Kml
Tg(Col2a1-cre)1Bhr/?		involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * SJL
Reduced rates of proliferation and cell survival in cartilage elements of Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr Bmpr1btm1Kml/Bmpr1btm1Kml Tg(Col2a1-cre)1Bhr/? embryosBmpr1atm2.1Bhr/Bmpr1atm2.1Bhr
Bmpr1btm1Kml/Bmpr1btm1Kml
Tg(Col2a1-cre)1Bhr/?		involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * SJL
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04/16/2024
MGI 6.23 		The Jackson Laboratory