Tg(Ccl5-EGFP)#Itan
Transgene Detail

Summary

• Symbol: Tg(Ccl5-EGFP)#Itan
• Name: transgene insertion, Ichiro Taniuchi
• MGI ID: MGI:7384498
• Synonyms: Ccl5-GFP BAC Tg
• Transgene: Tg(Ccl5-EGFP)#Itan Location: unknown
• Alliance: Tg(Ccl5-EGFP)#Itan page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(Ccl5-EGFP)#Itan expresses 13 genes
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ccl3 (MGI:98260)
  mouse	Ccl4 (MGI:98261)
  mouse	Ccl5 (MGI:98262)
  mouse	Ccl6 (MGI:98263)
  mouse	Ccl9 (MGI:104533)
  mouse	E230016K23Rik (MGI:3041204)
  mouse	Gm11433 (MGI:3651026)
  mouse	Gm23247 (MGI:5453024)
  mouse	Gm32650 (MGI:5591809)
  mouse	Gm38933 (MGI:5621818)
  mouse	Gm51868 (MGI:6365731)
  mouse	Gm53692 (MGI:6722429)
  mouse	Heatr9 (MGI:3650286)

• Mutation details: The transgene insert consists of BAC B6Ng01-015L02 where the Ccl5 coding region from start codon to stop codon (4741 bp) was replaced with the EGFP fluorescent reporter gene cDNA. The BAC also contains Ccl3, -4, -6 and -9, Heatr9 and the 3' end of Taf15. (J:287321)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:287321 Seo W, et al., Runx-mediated regulation of CCL5 via antagonizing two enhancers influences immune cell function and anti-tumor immunity. Nat Commun. 2020 Mar 26;11(1):1562
• All: 1 reference(s)