66 phenotypes from 7 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Adcy3Jll/Adcy3+ C57BL/6J-Adcy3Jll	decreased body weight	J:223554
	decreased brown fat cell size	J:223554
	decreased percent body fat/body weight	J:223554
	decreased susceptibility to diet-induced hepatic steatosis	J:223554
	decreased susceptibility to diet-induced obesity	J:223554
	decreased total body fat amount	J:223554
	decreased white fat cell size	J:223554
Adcy3Jll/Adcy3+ involves: 129S1/SvImJ * C57BL/6J	decreased body weight	J:223554
	decreased circulating glucose level	J:223554
	decreased circulating insulin level	J:223554
	decreased circulating leptin level	J:223554
	decreased percent body fat/body weight	J:223554
	decreased susceptibility to diet-induced obesity	J:223554
	decreased total body fat amount	J:223554
	hyperactivity	J:223554
	increased oxygen consumption	J:223554
Adcy3Jll/Adcy3Jll involves: 129S1/SvImJ * C57BL/6J	decreased body weight	J:223554
	decreased susceptibility to diet-induced obesity	J:223554
	decreased total body fat amount	J:223554
Adcy3tm1.1Dek/Adcy3tm1.1Dek Tg(AQP2-cre)2Dek/0 involves: C57BL/6 * CBA	normal renal/urinary system phenotype	J:207417
Adcy3tm1.1Hazh/Adcy3tm1.1Hazh involves: 129S6/SvEvTac * C57BL/6	abnormal olfactory system physiology	J:190988
Adcy3tm1a(EUCOMM)Wtsi/Adcy3+ C57BL/6N-Adcy3tm1a(EUCOMM)Wtsi/Wtsi	decreased lean body mass	J:211773
	increased hematocrit	J:211773
	increased hemoglobin content	J:211773
	increased total body fat amount	J:211773
Adcy3tm1a(EUCOMM)Wtsi/Adcy3tm1a(EUCOMM)Wtsi C57BL/6N-Adcy3tm1a(EUCOMM)Wtsi/Wtsi	preweaning lethality, incomplete penetrance	J:211773
Adcy3tm1Dgen/Adcy3+ involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:101679
Adcy3tm1Dgen/Adcy3tm1Dgen involves: 129P2/OlaHsd * C57BL/6	postnatal lethality, complete penetrance	J:101679
Adcy3tm1Drs/Adcy3+ involves: 129X1/SvJ * C57BL/6	impaired olfaction	J:64745
Adcy3tm1Drs/Adcy3tm1Drs involves: 129X1/SvJ * C57BL/6	abnormal fertility/fecundity	J:64745
	abnormal olfaction	J:83156
	abnormal olfactory bulb morphology	J:83156
	abnormal sensory neuron innervation pattern	J:83156
	anosmia	J:64745
	asthenozoospermia	J:97802
	decreased body weight	J:64745
	decreased circulating renin level	J:144961
	decreased litter size	J:97802
	decreased renal glomerular filtration rate	J:144961
	normal homeostasis/metabolism phenotype	J:144961
	impaired fertilization	J:97802
	impaired sperm capacitation	J:97802
	increased circulating creatinine level	J:144961
	obese	J:144961
	postnatal lethality, incomplete penetrance	J:64745
	premature acrosome reaction	J:97802
	reduced female fertility	J:97802
	reduced male fertility	J:97802
	normal renal/urinary system phenotype	J:144961
Adcy3tm1Drs/Adcy3tm1Drs involves: 129X1/SvJ * C57BL/6J	abnormal CNS synaptic transmission	J:281839
	abnormal dendrite arborization pattern	J:281839
	abnormal depression-related behavior	J:281839
	abnormal excitatory postsynaptic potential	J:281839
	abnormal hippocampus CA1 region morphology	J:281839
	abnormal long-term spatial reference memory	J:281839
	abnormal nest building behavior	J:281839
	abnormal neuron physiology	J:281839
	abnormal non-rapid eye movement sleep pattern	J:281839
	abnormal object recognition memory	J:281839
	abnormal response to new environment	J:281839
	abnormal social investigation	J:281839
	anosmia	J:281839
	behavioral despair	J:281839
	decreased brain size	J:281839
	decreased brain weight	J:281839
	decreased dentate gyrus size	J:281839
	decreased grooming behavior	J:281839
	decreased hippocampus volume	J:281839
	hypoactivity	J:281839
	impaired spatial learning	J:281839
	increased frequency of paradoxical sleep	J:281839
	polyphagia	J:281839
	reduced long-term potentiation	J:281839
	small hippocampus	J:281839
Adcy3tm2.1Drs/Adcy3tm2.1Drs Emx1tm1(cre)Krj/Emx1+ involves: 129S2/SvPas * 129X1/SvJ	abnormal depression-related behavior	J:281839
	abnormal long-term spatial reference memory	J:281839
	abnormal object recognition memory	J:281839
	abnormal response to new environment	J:281839
	behavioral despair	J:281839
	hypoactivity	J:281839
	impaired spatial learning	J:281839
Adcy3tm2.1Drs/Adcy3tm2.1Drs Ndor1Tg(UBC-cre/ERT2)1Ejb/Ndor1+ involves: 129 * 129X1/SvJ * C57BL/6	abnormal circadian sleep/wake cycle	J:281839
	abnormal nest building behavior	J:281839
	abnormal non-rapid eye movement sleep pattern	J:281839
	abnormal response to new environment	J:281839
	behavioral despair	J:281839
	decreased grooming behavior	J:281839
	hypoactivity	J:281839
	increased circulating corticosterone level	J:281839