Adcy3^tm1.1Dek
Targeted Allele Detail

Summary

• Symbol: Adcy3^tm1.1Dek
• Name: adenylate cyclase 3; targeted mutation 1.1, Donald E Kohan
• MGI ID: MGI:5606199
• Gene: Adcy3 Location: Chr12:4183397-4263525 bp, + strand Genetic Position: Chr12, 1.99 cM, cytoband A-B
• Alliance: Adcy3^tm1.1Dek page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:207417
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 4-6 were flanked with loxP sites and an FRT flanked neo cassette was inserted immediately 3' to the loxP site in intron 3 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:207417)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adcy3 Mutation: 42 strains or lines available

References

• Original: J:207417 Kittikulsuth W, et al., Lack of an effect of collecting duct-specific deletion of adenylyl cyclase 3 on renal Na+ and water excretion or arterial pressure. Am J Physiol Renal Physiol. 2014 Mar;306(6):F597-607
• All: 2 reference(s)