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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Sptb
spectrin beta, erythrocytic
MGI:98387
61 phenotypes from 3 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Sptbem1(IMPC)J/Sptb+
C57BL/6NJ-Sptbem1(IMPC)J/Mmjax
decreased exploration in new environment J:211773
decreased mean corpuscular hemoglobin J:211773
decreased mean corpuscular volume J:211773
increased erythrocyte cell number J:211773
Sptbem1(IMPC)J/Sptbem1(IMPC)J
C57BL/6NJ-Sptbem1(IMPC)J/Mmjax
embryonic lethality prior to organogenesis J:211773
preweaning lethality, complete penetrance J:211773
Sptbja/Sptb+
129/Sv-Sptbja
anemia J:5985
increased erythrocyte protoporphyrin level J:5985
Sptbja/Sptb+
(WB.129-Sptbja/J x B6.129-Sptbja/J)F1
increased erythrocyte clearance J:44313
increased erythrocyte osmotic fragility J:44313
Sptbja/Sptb+
involves: 129/Sv * C57BL/6J * WB/Re
increased erythrocyte protoporphyrin level J:5985
Sptbja/Sptbja
129/Sv-Sptbja
abnormal reticulocyte morphology J:7501
anisocytosis J:305
enlarged heart J:305
enlarged liver J:305
enlarged spleen J:305
hemolytic anemia J:305
jaundice J:305
multifocal hepatic necrosis J:305
neonatal lethality, incomplete penetrance J:7501
poikilocytosis J:305
prenatal lethality, incomplete penetrance J:305
reticulocytosis J:305
Sptbja/Sptbja
(WB.129-Sptbja/J x B6.129-Sptbja/J)F1
abnormal cardiac thrombosis J:44313, J:62355
abnormal erythrocyte morphology J:62355
abnormal erythrocyte osmotic lysis J:162532
abnormal erythrocyte physiology J:162532
abnormal myocardium layer morphology J:44313
anisopoikilocytosis J:162532
brain lesion J:44313
cardiac hypertrophy J:162532
cerebral infarct J:44313
decreased body size J:162532
decreased brain size J:44313
decreased cellular hemoglobin content J:44313
decreased circulating glucose level J:44313
decreased erythrocyte cell number J:44313
decreased hematocrit J:44313, J:162532
decreased hemoglobin content J:44313, J:162532
decreased total body fat amount J:44313
enlarged heart J:44313
enlarged liver J:44313, J:162532
enlarged spleen J:44313, J:162532
extramedullary hematopoiesis J:162532
glomerulonephritis J:44313
hemolysis J:162532
hemolytic anemia J:162532
hydronephrosis J:44313
increased blood urea nitrogen level J:44313
increased circulating bilirubin level J:44313, J:162532
increased circulating iron level J:44313
increased erythrocyte clearance J:162532
increased kidney iron level J:44313
increased nucleated erythrocyte cell number J:162532
increased spleen red pulp amount J:44313
infertility J:162532
jaundice J:162532
low mean erythrocyte cell number J:162532
microcytosis J:62355
neonatal lethality, incomplete penetrance J:162532
poikilocytosis J:162532
postnatal lethality, incomplete penetrance J:44313, J:162532
premature death J:44313
renal tubular necrosis J:44313
reticulocytosis J:44313, J:162532
schistocytosis J:162532
tubular nephritis J:44313
urolithiasis J:44313
Sptbja/Sptbja
involves: 129/Sv * C57BL/6J * WB/Re
increased erythrocyte protoporphyrin level J:5985
Sptbm1Jus/Sptbm1Jus
involves: 129S6/SvEvTac * C57BL/6
abnormal erythrocyte morphology J:159750
acanthocytosis J:159750
anemia J:159750
enlarged heart J:159750
enlarged kidney J:159750
enlarged liver J:159750
enlarged spleen J:159750
hemolysis J:159750
spherocytosis J:159750

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory