Gt(ROSA)26Sortm1(CAG-Sox2,-EGFP)Blh/Gt(ROSA)26Sor+
Tg(Sftpc-cre)1Blh/0
involves: 129S/SvEv * C57BL/6 * DBA/2
|
abnormal lung morphology |
J:161806
|
|
bronchial epithelial hyperplasia |
J:161806
|
|
bronchiolar epithelial hyperplasia |
J:161806
|
|
increased lung adenocarcinoma incidence |
J:161806
|
|
lung epithelium hyperplasia |
J:161806
|
|
premature death |
J:161806
|
|
respiratory distress |
J:161806
|
Gt(ROSA)26Sortm1(CAG-Sox2,-EGFP)Blh/Gt(ROSA)26Sor+
Scgb1a1tm1(cre/ERT)Blh/Scgb1a1+
involves: 129S6/SvEv * C57BL/6
|
bronchial epithelial hyperplasia |
J:161806
|
|
normal
neoplasm |
J:161806
|
Gt(ROSA)26Sortm1(CAG-Sox2,-EGFP)Blh/Gt(ROSA)26Sortm1(CAG-Sox2,-EGFP)Blh
Scgb1a1tm1(cre/ERT)Blh/Scgb1a1+
involves: 129S6/SvEv * C57BL/6
|
bronchial epithelial hyperplasia |
J:161806
|
|
increased lung adenocarcinoma incidence |
J:161806
|
Sox2em1(IMPC)Mbp/Sox2+
C57BL/6N-Sox2em1(IMPC)Mbp/MbpMmucd
|
abnormal brain morphology |
J:211773
|
|
abnormal optic disk morphology |
J:211773
|
|
abnormal retina blood vessel morphology |
J:211773
|
|
embryonic growth retardation |
J:211773
|
|
enhanced contextual conditioning behavior |
J:211773
|
|
irregularly shaped pupil |
J:211773
|
Sox2em1(IMPC)Mbp/Sox2em1(IMPC)Mbp
C57BL/6N-Sox2em1(IMPC)Mbp/MbpMmucd
|
embryonic lethality prior to organogenesis |
J:211773
|
|
preweaning lethality, complete penetrance |
J:211773
|
Sox2tm1.1Knd/Sox2tm1.1Knd
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
normal
embryo phenotype |
J:217059
|
Sox2tm1.1Lan/Sox2tm1.1Lan
Tg(Cryaa-cre)10Mlr/0
involves: C57BL/6 * FVB/N * SJL
|
normal
vision/eye phenotype |
J:152850
|
Sox2tm1.1Lan/Sox2tm1.1Lan
Tg(Scgb1a1-cre)1Kkw/0
involves: 129/Sv * C57BL/6
|
abnormal bronchiole epithelium morphology |
J:155963
|
|
abnormal lung epithelium morphology |
J:155963
|
|
abnormal respiratory mucosa goblet cell morphology |
J:155963
|
|
absent club cells |
J:155963
|
|
absent respiratory motile cilia |
J:155963
|
|
absent respiratory mucosa goblet cells |
J:155963
|
Sox2tm1.1Vep/Sox2+
Not Specified
|
no abnormal phenotype detected |
J:99610
|
Sox2tm1.1Vep/Sox2tm1.2Vlcg
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac
|
absent egg cylinders |
J:191980
|
|
absent embryonic epiblast |
J:191980
|
|
embryonic lethality between implantation and placentation, complete penetrance |
J:191980
|
|
increased trophoblast giant cell number |
J:191980
|
Sox2tm1.1Vlcg/Sox2tm1.1Vlcg
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac
|
normal
behavior/neurological phenotype |
J:191980
|
|
normal
growth/size/body region phenotype |
J:191980
|
Sox2tm1.1Vlcg/Sox2tm1.1Vlcg
involves: 129S6/SvEvTac * C57BL/6NTac
|
no abnormal phenotype detected |
J:200671
|
Sox2tm1.2Vlcg/Sox2+
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac
|
no abnormal phenotype detected |
J:191980
|
Sox2tm1.2Vlcg/Sox2tm1.2Vlcg
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac
|
absent egg cylinders |
J:191980
|
|
absent embryonic epiblast |
J:191980
|
|
embryonic lethality between implantation and placentation, complete penetrance |
J:191980
|
|
increased trophoblast giant cell number |
J:191980
|
Sox2tm1Lpev/Sox2+
Not Specified
|
no abnormal phenotype detected |
J:108452
|
Sox2tm1Lpev/Sox2tm2Lpev
involves: 129S/SvEv * C57BL/6
|
abnormal digestive system physiology |
J:122531
|
|
abnormal esophageal squamous epithelium morphology |
J:122531
|
|
abnormal esophagus morphology |
J:122531
|
|
abnormal stomach morphology |
J:122531
|
|
esophageal atresia |
J:122531
|
|
neonatal lethality, complete penetrance |
J:122531
|
|
respiratory distress |
J:122531
|
|
tracheoesophageal fistula |
J:122531
|
Sox2tm1Lpev/Sox2tm2Lpev
Tg(Pax6-cre,GFP)2Pgr/?
involves: 129S/SvEv
|
abnormal eye size |
J:108452
|
Sox2tm1Lpev/Sox2tm3Lpev
involves: 129S/SvEv
|
abnormal esophagus morphology |
J:112945
|
|
abnormal fungiform papillae morphology |
J:112945
|
|
abnormal stomach morphology |
J:112945
|
|
abnormal tongue morphology |
J:112945
|
|
absent palatal taste bud |
J:112945
|
|
anophthalmia |
J:108452
|
|
normal
digestive/alimentary phenotype |
J:112945
|
|
disorganized retina layers |
J:108452
|
|
microphthalmia |
J:108452
|
|
neonatal lethality, complete penetrance |
J:112945
|
|
retina hyperplasia |
J:108452
|
Sox2tm1Lpev/Sox2tm4Lpev
involves: 129S/SvEv
|
anophthalmia |
J:108452
|
|
disorganized retina layers |
J:108452
|
|
microphthalmia |
J:108452
|
|
optic nerve hypoplasia |
J:108452
|
|
retina hyperplasia |
J:108452
|
Sox2tm1Lpev/Sox2tm4Lpev
involves: 129S/SvEv * CD-1
|
cleft secondary palate |
J:223203
|
|
delayed palatal shelf elevation |
J:223203
|
|
failure of palatal shelf elevation |
J:223203
|
|
microphthalmia |
J:223203
|
|
palatal shelves fail to meet at midline |
J:223203
|
Sox2tm1Okud/Sox2tm1Okud
Tg(Nes-cre)1Sasa/?
involves: 129P2/OlaHsd * C57BL/6
|
abnormal neuronal precursor proliferation |
J:138323
|
|
enlarged lateral ventricles |
J:138323
|
|
neonatal lethality, complete penetrance |
J:138323
|
Sox2tm1Rlb/Sox2+
involves: 129S/SvEv
|
reduced male fertility |
J:81180
|
Sox2tm1Rlb/Sox2+
involves: 129S/SvEv * MF1
|
abnormal adenohypophysis development |
J:114458
|
|
abnormal pituitary gland morphology |
J:114458
|
|
abnormal seminiferous tubule morphology |
J:114458
|
|
bifurcated Rathke's pouch |
J:114458
|
|
decreased adrenocorticotropin level |
J:114458
|
|
decreased body size |
J:114458
|
|
decreased growth hormone level |
J:114458
|
|
decreased luteinizing hormone level |
J:114458
|
|
decreased prolactin level |
J:114458
|
|
decreased somatotroph cell number |
J:114458
|
|
decreased thyroid-stimulating hormone level |
J:114458
|
|
normal
digestive/alimentary phenotype |
J:114458
|
|
oligozoospermia |
J:114458
|
|
postnatal lethality, incomplete penetrance |
J:114458
|
|
reduced male fertility |
J:81180,
J:114458
|
|
small adenohypophysis |
J:114458
|
|
small testis |
J:114458
|
|
normal
vision/eye phenotype |
J:114458
|
Sox2tm1Rlb/Sox2tm1Rlb
either: (involves: 129S/SvEv) or (involves: 129S/SvEv * MF1)
|
abnormal ectoderm development |
J:81180
|
|
absent ectoplacental cone |
J:81180
|
|
absent egg cylinders |
J:81180
|
|
embryonic lethality between implantation and somite formation, complete penetrance |
J:81180
|
Sox2tm1Rlb/Sox2ysb
involves: 129S/SvEv * C57BL/6 * CBA
|
abnormal semicircular canal morphology |
J:98458
|
|
abnormal sulcus ampullaris morphology |
J:98458
|
|
abnormal vestibular saccule morphology |
J:98458
|
|
circling |
J:98458
|
|
deafness |
J:98458
|
|
yellow coat color |
J:98458
|
Sox2tm1Vep/Sox2+
Not Specified
|
no abnormal phenotype detected |
J:99610
|
Sox2tm2Lpev/Sox2+
involves: 129S/SvEv
|
no abnormal phenotype detected |
J:108452
|
Sox2tm2Lpev/Sox2tm2.1Lpev
Tg(Pax6-cre,GFP)2Pgr/?
involves: 129S/SvEv
|
abnormal retina morphology |
J:108452
|
|
retina hypoplasia |
J:108452
|
Sox2tm2Lpev/Sox2tm2Lpev
involves: 129S/SvEv
|
no abnormal phenotype detected |
J:108452
|
Sox2tm2Lpev/Sox2tm2Lpev
Tg(Pax6-cre,GFP)2Pgr/?
involves: 129S/SvEv
|
abnormal eye size |
J:108452
|
|
abnormal retina progenitor cell morphology |
J:108452
|
Sox2tm2Lpev/Sox2tm3Lpev
involves: 129S/SvEv * C57BL/6
|
abnormal Ebner's gland morphology |
J:122531
|
|
abnormal epiglottis morphology |
J:122531
|
|
abnormal esophageal squamous epithelium morphology |
J:122531
|
|
abnormal esophagus morphology |
J:122531
|
|
abnormal salivary gland morphology |
J:122531
|
|
abnormal stomach morphology |
J:122531
|
|
absent anterior lingual gland |
J:122531
|
|
absent palatine gland |
J:122531
|
|
normal
digestive/alimentary phenotype |
J:122531
|
|
neonatal lethality, complete penetrance |
J:122531
|
|
respiratory distress |
J:122531
|
|
normal
respiratory system phenotype |
J:122531
|
Sox2tm2Skn/Sox2tm3Skn
involves: 129S/SvEv * 129S1/Sv * C57BL/6J
|
abnormal brain morphology |
J:92063
|
|
abnormal cerebral cortex morphology |
J:92063
|
|
abnormal ependyma morphology |
J:92063
|
|
abnormal nervous system morphology |
J:92063
|
|
abnormal nervous system physiology |
J:92063
|
|
abnormal neuron differentiation |
J:92063
|
|
abnormal thalamus morphology |
J:92063
|
|
bidirectional circling |
J:92063
|
|
decreased body size |
J:92063
|
|
decreased corpus callosum size |
J:92063
|
|
dystonia |
J:92063
|
|
enlarged lateral ventricles |
J:92063
|
|
enlarged third ventricle |
J:92063
|
|
motor neuron degeneration |
J:92063
|
|
nonconvulsive seizures |
J:92063
|
|
premature death |
J:92063
|
|
prenatal lethality, incomplete penetrance |
J:92063
|
Sox2tm2Skn/Sox2tm4.1Skn
Tg(Nes-cre)1Kln/0
either: (involves: 129S/Sv * C57BL/6 * SJL) or (involves: 129S/Sv * C57BL/6 * DBA/2 * SJL)
|
abnormal cerebral cortex morphology |
J:154650
|
|
abnormal corpus callosum morphology |
J:154650
|
|
abnormal dentate gyrus morphology |
J:154650
|
|
abnormal hippocampus development |
J:154650
|
|
abnormal neuron differentiation |
J:154650
|
|
absent dentate gyrus |
J:154650
|
|
enlarged lateral ventricles |
J:154650
|
|
loss of hippocampal neurons |
J:154650
|
|
premature death |
J:154650
|
|
small hippocampus |
J:154650
|
Sox2tm3Lpev/Sox2+
involves: 129S/SvEv
|
no abnormal phenotype detected |
J:108452
|
Sox2tm3Lpev/Sox2tm3Lpev
involves: 129S/SvEv
|
no abnormal phenotype detected |
J:108452
|
Sox2tm4.1Skn/Sox2tm4.1Skn
Tbx18tm2.1(cre)Sev/Tbx18+
involves: 129S1/Sv
|
abnormal hair growth |
J:191082
|
|
normal
integument phenotype |
J:191082
|
Sox2tm4.1Skn/Sox2tm4.1Skn
Tg(Sox2-cre/ERT2)1Skn/0
involves: 129S1/Sv * 129S4/SvJae
|
abnormal neuron differentiation |
J:154650
|
|
abnormal neuronal precursor proliferation |
J:154650
|
|
abnormal radial glial cell morphology |
J:154650
|
Sox2tm4Lpev/Sox2+
involves: 129S/SvEv
|
no abnormal phenotype detected |
J:108452
|
Sox2tm4Lpev/Sox2tm4Lpev
involves: 129S/SvEv
|
no abnormal phenotype detected |
J:108452
|
Sox2ysb/Sox2+
involves: C57BL/6 * CBA
|
yellow coat color |
J:77358
|
Sox2ysb/Sox2ysb
involves: C57BL/6 * CBA
|
abnormal auchene hair morphology |
J:77358
|
|
abnormal awl hair morphology |
J:77358
|
|
abnormal cochlear hair cell morphology |
J:98458
|
|
abnormal inner ear morphology |
J:98458
|
|
abnormal pinna reflex |
J:77358
|
|
abnormal placing response |
J:77358
|
|
abnormal semicircular canal morphology |
J:98458
|
|
abnormal sulcus ampullaris morphology |
J:98458
|
|
abnormal zigzag hair morphology |
J:77358
|
|
absent vestibular hair cells |
J:98458
|
|
circling |
J:77358
|
|
deafness |
J:77358
|
|
decreased cochlea coiling |
J:98458
|
|
decreased cochlear nerve compound action potential |
J:77358
|
|
dilated cochlea |
J:98458
|
|
head tossing |
J:77358
|
|
impaired righting response |
J:77358
|
|
impaired swimming |
J:77358
|
|
yellow coat color |
J:77358
|
Excel File
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