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Tg(Sox2-cre/ERT2)1Skn
Transgene Detail
Summary
Symbol: Tg(Sox2-cre/ERT2)1Skn
Name: transgene insertion 1, Silvia K Nicolis
MGI ID: MGI:4397776
Synonyms: Sox2-creERT2
Transgene: Tg(Sox2-cre/ERT2)1Skn  Location: unknown  
Alliance: Tg(Sox2-cre/ERT2)1Skn page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Sox2-cre/ERT2)1Skn expression driven by 1 gene
 
Mutation details5.7 kb of the 5' telencephalic enhancer/promoter was used to drive inducible, telencephalic-specific expression of a cre/estrogen receptor (ERT2) fusion. Six lines were created and the one with the most efficient activity was used in subsequent experiments. (J:154650)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Sox2 (species not specified)
Summary of all recombinase alleles driven by Sox2.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:154650 Favaro R, et al., Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh. Nat Neurosci. 2009 Oct;12(10):1248-56
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/05/2024
MGI 6.24
The Jackson Laboratory