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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Rac1
Rac family small GTPase 1
MGI:97845
16 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
\Cd19tm1(cre)Cgn/\Cd19+
\Rac1tm1Tyb/\Rac1tm1Tyb
\Rac2tm1Mddw/\Rac2tm1Mddw
involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * C57BL/6 		arrested B cell differentiation J:86765
decreased B cell number J:86765
decreased B-1 B cell number J:86765
decreased follicular B cell number J:86765
decreased marginal zone B cell number J:86765
decreased transitional stage B cell number J:86765
\Ctnnb1tm2Kem/\Ctnnb1tm2Kem
\Rac1tm1Djk/\Rac1+
\Tg(Msx2-cre)5Rem/0
involves: 129S4/SvJae 		abnormal forelimb morphology J:145305
absent hindlimb J:145305
\Grhl3tm1(cre)Cgh/\Grhl3+
\Gt(ROSA)26Sortm1(ptxA)Cgh/\Gt(ROSA)26Sor+
\Rac1tm1Djk/\Rac1tm1Djk
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * SJL 		exencephaly J:157446
spina bifida J:157446
\Gt(ROSA)26Sortm1(Dkk1)Flng/\Gt(ROSA)26Sor+
\Rac1tm1Djk/\Rac1+
\Tg(Msx2-cre)5Rem/0
involves: 129S4/SvJae * 129X1/SvJ 		absent hindlimb J:145305
short forelimb J:145305
\Gt(ROSA)26Sortm9(Rac1*,-EGFP)Rsky/\Gt(ROSA)26Sortm9(Rac1*,-EGFP)Rsky
\Igh-Jtm1Cgn/\Ightm4Cgn
\Tg(Cr2-cre)3Cgn/0
involves: 129P2/OlaHsd * C57BL/6 		decreased mature B cell number J:157297
\Ptentm1Ppp/\Pten+
\Rac1tm1Tyb/\Rac1tm2Tyb
\Edil3Tg(Sox2-cre)1Amc/\Edil3+
involves: 129S/Sv * C3H * C57BL/6 * CBA 		abnormal apoptosis J:173526
abnormal embryo development J:173526
\Rac1tm1Djk/\Rac1tm1Djk
\Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/\Gt(ROSA)26Sor+
\Tg(Mef2c-cre)2Blk/0
involves: 129 * BALB/c * C57BL/6 * C57BL/6J 		abnormal interventricular septum muscular part morphology J:315097
decreased cell migration J:315097
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory