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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pln
phospholamban
MGI:97622
43 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Atp2a2tm1Fwuy/Atp2a2tm1Fwuy
Plntm1Egk/Plntm1Egk
involves: 129 * FVB/N * Swiss 		abnormal calcium ion homeostasis J:110974
abnormal cardiac muscle relaxation J:110974
abnormal cardiac output J:110974
abnormal locomotor activation J:110974
cardiac hypertrophy J:110974
congestive heart failure J:110974
decreased cardiac stroke volume J:110974
decreased heart rate J:110974
globular heart J:110974
increased heart left ventricle wall thickness J:110974
increased heart weight J:110974
increased myocardial fiber size J:110974
premature death J:110974
thick ventricular wall J:110974
Csrp3tm1Crni/Csrp3tm1Crni
Plntm1Egk/Plntm1Egk
involves: 129S2/SvPas * CF-1 		cardiac hypertrophy J:58299
decreased heart rate J:58299
increased cardiac muscle contractility J:58299
Hprt1tm1Dhm/Hprt1tm1Dhm
Plntm1Egk/Plntm1Egk
involves: 129P2/OlaHsd * 129S2/SvPas 		abnormal cardiac muscle relaxation J:106044
abnormal myocardial fiber physiology J:106044
increased cardiac muscle contractility J:106044
Hprt1tm1Dhm/Y
Plntm1Egk/Plntm1Egk
involves: 129P2/OlaHsd * 129S2/SvPas 		abnormal cardiac muscle relaxation J:106044
abnormal myocardial fiber physiology J:106044
increased cardiac muscle contractility J:106044
Plntm1Egk/Plntm1Egk
Tg(Myh6*)140Lnwd/0
involves: 129S2/SvPas * CBA * CF-1 * FVB/N 		increased heart weight J:134706
Plntm1Egk/Plntm1Egk
Tg(Myh6/tetO-Tnnc1*I61Q)1Jmol/0
Tg(Myh6-tTA)55Rbns/0
involves: 129S2/SvPas * FVB 		abnormal interventricular septum morphology J:234490
abnormal myocardial fiber calcium currents J:234490
abnormal myocardial fiber physiology J:234490
increased heart left ventricle size J:234490
increased heart weight J:234490
Plntm1Egk/Plntm1Egk
Tnnt2tm2.1Feah/Tnnt2+
involves: 129S2/SvPas * 129S6/SvEvTac * FVB/N 		decreased cardiac muscle contractility J:243725
dilated cardiomyopathy J:243725
dilated heart left ventricle J:243725
Plntm1Egk/Plntm1Egk
Zdhhc16tm1Goff/Zdhhc16tm1Goff
involves: 129S1/Sv * 129S2/SvPas 		abnormal eye development J:228307
normal cardiovascular system phenotype J:228307
neonatal lethality, complete penetrance J:228307
Tg(Myh6-AIP/PLN*)46Jded/0
FVB/N-Tg(Myh6-AIP/PLN*)46Jded 		abnormal cardiac muscle relaxation J:84333
abnormal heart atrium morphology J:84333
abnormal heart ventricle morphology J:84333
cardiac fibrosis J:84333
cardiac hypertrophy J:84333
congestive heart failure J:84333
decreased heart rate J:84333
increased heart left atrium size J:84333
increased heart left ventricle size J:84333
increased heart rate J:84333
increased heart weight J:84333
increased left ventricle diastolic pressure J:84333
increased left ventricle systolic pressure J:84333
increased lung weight J:84333
Tg(Myh6-Pln*R9C)#Ces/0
involves: FVB/N 		abnormal myocardial fiber physiology J:82353
cardiac interstitial fibrosis J:82353
congestive heart failure J:82353
cyanosis J:82353
decreased ventricle muscle contractility J:82353
dilated cardiomyopathy J:82353
dilated heart left ventricle J:82353
dilated heart ventricle J:82353
enlarged heart J:82353
enlarged liver J:82353
increased heart left atrium size J:82353
increased myocardial fiber size J:82353
lethargy J:82353
pericardial effusion J:82353
pleural effusion J:82353
premature death J:82353
respiratory distress J:82353
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory