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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pdgfrb
platelet derived growth factor receptor, beta polypeptide
MGI:97531
80 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cdkn2atm1Cjs/Cdkn2atm1Cjs
Pdgfrbtm1Sor/Pdgfrbtm1Sor
involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 		abnormal vitreous body morphology J:101016
Cdkn2atm3(cre)Cjs/Cdkn2atm4Cjs
Pdgfrbtm11Sor/Pdgfrbtm11Sor
involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6 		normal vision/eye phenotype J:147752
Myo1eGt(ROSA)74Sor/Myo1eGt(ROSA)74Sor
Pdgfrbtm1Sor/Pdgfrb+
involves: 129S4/SvJaeSor * 129S7/SvEvBrd 		abnormal kidney physiology J:117491
abnormal renal glomerulus morphology J:117491
abnormal smooth muscle morphology J:117491
normal hematopoietic system phenotype J:117491
increased blood urea nitrogen level J:117491
Pdgfratm5Sor/Pdgfratm5Sor
Pdgfrbtm3Sor/Pdgfrbtm3Sor
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6J) 		embryonic growth retardation J:73817
failure of chorioallantoic fusion J:73817
fetal bleb J:73817
incomplete embryo turning J:73817
midline facial cleft J:73817
open neural tube J:73817
rib fusion J:73817
Pdgfratm8Sor/Pdgfratm8Sor
Pdgfrbtm1Mdt/Pdgfrbtm1Mdt
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: C57BL/6 * CBA 		abnormal cardiac neural crest cell migration J:122584
abnormal thymus development J:122584
cleft palate J:122584
cyanosis J:122584
perinatal lethality, complete penetrance J:122584
persistent truncus arteriosus J:122584
retroesophageal right subclavian artery J:122584
thymus hypoplasia J:122584
ventricular septal defect J:122584
Pdgfratm8Sor/Pdgfratm8Sor
Pdgfrbtm11Sor/Pdgfrbtm11Sor
Tg(Nr5a1-cre)2Klp/0
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) 		abnormal adrenal cortex morphology J:142042
abnormal adrenal gland morphology J:142042
abnormal testis morphology J:142042
perinatal lethality, incomplete penetrance J:142042
small adrenal glands J:142042
small testis J:142042
testicular hemorrhage J:142042
Pdgfrbtm1Sor/Pdgfrb+
Sgpl1Gt(ROSA)78Sor/Sgpl1Gt(ROSA)78Sor
either: (involves: 129S4/SvJaeSor * 129S7/SvEvBrd) or (involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6) 		female infertility J:142042
male infertility J:142042
Pdgfrbtm1Sor/Pdgfrb+
Plekha1Gt(ROSA)82Sor/Plekha1Gt(ROSA)82Sor
either: (involves: 129S4/SvJaeSor * 129S7/SvEvBrd) or (involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6) 		male infertility J:142042
Pdgfrbtm1Sor/Pdgfrb+
TiparpGt(ROSA)79Sor/TiparpGt(ROSA)79Sor
either: (involves: 129S4/SvJaeSor * 129S7/SvEvBrd) or (involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6) 		female infertility J:142042
Pdgfrbtm1Sor/Pdgfrb+
Schip1Gt(ROSA)77Sor/Schip1Gt(ROSA)77Sor
involves: 129S4/SvJaeSor * 129S7/SvEvBrd 		abnormal kidney physiology J:117491
abnormal renal glomerulus morphology J:117491
abnormal skeleton morphology J:117491
abnormal smooth muscle morphology J:117491
increased blood urea nitrogen level J:117491
Pdgfrbtm1Sor/Pdgfrbtm3Sor
involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 		abnormal pericyte morphology J:86542
Pdgfrbtm1Sor/Pdgfrbtm4Sor
involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 		abnormal pericyte morphology J:86542
Pdgfrbtm1Sor/Pdgfrbtm5Sor
either: (involves: 129S4/SvJaeSor * 129S7/SvEvBrd) or (involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6) 		abnormal eye morphology J:67735
abnormal heart left ventricle morphology J:67735
abnormal mesangial cell morphology J:67735
abnormal pericyte morphology J:67735
abnormal renal glomerulus morphology J:67735
abnormal retina vasculature morphology J:67735
decreased body size J:67735
dilated heart right ventricle J:67735
enlarged heart J:67735
glomerulosclerosis J:67735
hemorrhage J:67735
kidney cyst J:67735
kidney microaneurysm J:67735
myocardial fiber disarray J:67735
perinatal lethality, incomplete penetrance J:67735
postnatal lethality, incomplete penetrance J:67735
retina detachment J:67735
retina hemorrhage J:67735
Pdgfrbtm1Sor/Pdgfrbtm6Sor
either: (involves: 129S4/SvJaeSor * 129S7/SvEvBrd) or (involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6) 		no abnormal phenotype detected J:67735
Pdgfrbtm3Sor/Pdgfrbtm3Sor
involves: 129S4/SvJae * C57BL/6 		abnormal pericyte morphology J:86542
Pdgfrbtm4Sor/Pdgfrbtm4Sor
either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6) 		abnormal kidney physiology J:66516
abnormal mesangial cell morphology J:66516
normal cardiovascular system phenotype J:66516
decreased fibroblast proliferation J:66516
decreased kidney cell proliferation J:66516
Pdgfrbtm4Sor/Pdgfrbtm4Sor
involves: 129S4/SvJae * C57BL/6 		abnormal pericyte morphology J:86542
Pdgfrbtm5Sor/Pdgfrbtm5Sor
either: 129S4/SvJaeSor-Pdgfratm5Sor or (involves: 129S4/SvJaeSor * C57BL/6) 		abnormal glomerular capillary thrombosis J:67735
enlarged heart J:67735
increased susceptibility to injury J:67735
Pdgfrbtm14(Pdgfrb)Sor/Pdgfrb+
Meox2tm1(cre)Sor/Meox2+
involves: 129S4/SvJaeSor * C57BL/6 		postnatal growth retardation J:173602
postnatal lethality, complete penetrance J:173602
Pdgfrbtm14(Pdgfrb)Sor/Pdgfrb+
Tg(Prm-cre)70Og/0
involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6 		postnatal growth retardation J:173602
postnatal lethality, complete penetrance J:173602
Pdgfrbtm14(Pdgfrb)Sor/Pdgfrb+
Tg(Tagln-cre)1Her/0
involves: 129S4/SvJaeSor * C57BL/6 * SJL 		abnormal abdominal aorta morphology J:173602
abnormal adipose tissue morphology J:173602
abnormal aorta morphology J:173602
abnormal aorta tunica media morphology J:173602
abnormal aortic arch morphology J:173602
abnormal brain vasculature morphology J:173602
abnormal capillary morphology J:173602
abnormal descending aorta morphology J:173602
abnormal pericyte morphology J:173602
abnormal retina vasculature morphology J:173602
abnormal thoracic aorta morphology J:173602
dilated aorta J:173602
normal growth/size/body region phenotype J:173602
increased aorta wall thickness J:173602
increased vascular smooth muscle cell proliferation J:173602
normal mortality/aging J:173602
vascular smooth muscle hyperplasia J:173602
Pdgfrbtm14(Pdgfrb)Sor/Pdgfrb+
Tg(Tek-cre)1Ywa/0
involves: 129S4/SvJaeSor * C57BL/6 * SJL 		no abnormal phenotype detected J:173602
Pdgfrbtm14(Pdgfrb)Sor/Pdgfrb+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S4/SvJaeSor * C57BL/6 * CBA 		abnormal ascending aorta morphology J:173602
abnormal hypodermis fat layer morphology J:173602
abnormal inguinal fat pad morphology J:173602
abnormal mesenteric fat pad morphology J:173602
abnormal white adipose tissue morphology J:173602
abnormal white fat cell differentation J:173602
normal adipose tissue phenotype J:173602
increased white fat cell number J:173602
postnatal growth retardation J:173602
postnatal lethality, complete penetrance J:173602
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory