Pax7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pax7
paired box 7
MGI:97491

33 phenotypes from 9 alleles in 12 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
\Pax7^tm1(cre)Mrc/\Pax7^tm1(cre)Mrc involves: 129S1/Sv * 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:93443
\Pax7^{tm1(cre/Esr1)Cklr}/\Pax7^{tm1(cre/Esr1)Cklr} involves: 129S1/Sv * 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:157754
\Pax7^{tm1.1(KOMP)Vlcg}/\Pax7⁺ C57BL/6N-Pax7^{tm1.1(KOMP)Vlcg}/J	decreased circulating triglyceride level	J:211773
\Pax7^{tm1.1(KOMP)Vlcg}/\Pax7^{tm1.1(KOMP)Vlcg} C57BL/6N-Pax7^{tm1.1(KOMP)Vlcg}/J	preweaning lethality, incomplete penetrance	J:211773
\Pax7^{tm1.1(KOMP)Vlcg}/\Pax7^{tm1.1(KOMP)Vlcg} C57BL/6N-Pax7^{tm1.1(KOMP)Vlcg}/Ucd	preweaning lethality, complete penetrance	J:211773
\Pax7^{tm1.1(rtTA)Sjl}/\Pax7^{tm1.1(rtTA)Sjl} involves: 129S1/Sv * 129X1/SvJ * C57BL/6	cachexia	J:188599
	decreased body size	J:188599
	decreased skeletal muscle weight	J:188599
	postnatal lethality, incomplete penetrance	J:188599
\Pax7^tm1.1Thbr/\Pax7^tm1.1Thbr Not Specified	abnormal skeletal muscle satellite cell proliferation	J:202693
\Pax7^tm1.1Thbr/\Pax7^tm1.1Thbr \Myf5^tm1(cre)Mrc/\Myf5⁺ involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ	decreased satellite cell number	J:202693
\Pax7^tm1.1Thbr/\Pax7^tm1.1Thbr \Myf5^tm3(cre)Sor/\Myf5⁺ involves: 129S4/SvJaeSor	decreased body size	J:202693
	decreased satellite cell number	J:202693
	decreased skeletal muscle fiber diameter	J:202693
	decreased skeletal muscle fiber number	J:202693
	impaired skeletal muscle regeneration	J:202693
\Pax7^tm1.1Thbr/\Pax7^tm1.1Thbr \Tg(CMV-cre)1Cgn/0 involves: BALB/cJ	abnormal muscle morphology	J:202693
	decreased satellite cell number	J:202693
\Pax7^tm1.1Thbr/\Pax7^{tm2.1(cre/ERT2)Fan} involves: 129S1/Sv * 129X1/SvJ	abnormal muscle regeneration	J:202693
	abnormal skeletal muscle morphology	J:202693
	abnormal skeletal muscle satellite cell proliferation	J:202693
	decreased satellite cell number	J:202693
	decreased skeletal muscle size	J:202693
	normal muscle phenotype	J:202693
	skeletal muscle fibrosis	J:202693
	skeletal muscle necrosis	J:202693
\Pax7^tm1.2Fan/\Pax7^tm1.2Fan involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	impaired skeletal muscle regeneration	J:150962
	skeletal muscle fibrosis	J:150962
\Pax7^tm1Pgr/\Pax7^tm1Pgr involves: 129S2/SvPas	abnormal muscle regeneration	J:64793
	abnormal nasal capsule morphology	J:32018
	abnormal serous gland morphology	J:32018
	normal cellular phenotype	J:64793
	decreased skeletal muscle fiber diameter	J:64793
	normal digestive/alimentary phenotype	J:32018
	normal embryo phenotype	J:32018
	normal muscle phenotype	J:32018
	muscle weakness	J:64793
	normal nervous system phenotype	J:32018
	pointed snout	J:32018
	postnatal growth retardation	J:32018, J:64793
	postnatal lethality, incomplete penetrance	J:32018
	premature death	J:32018
	short maxilla	J:32018
	thin diaphragm muscle	J:64793
\Pax7^tm2Pgr/\Pax7^tm2Pgr either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: 129S2/SvPas * C57BL/6)	abnormal muscle regeneration	J:92280
	decreased satellite cell number	J:92280
\Pax7^tm2Pgr/\Pax7^tm2Pgr either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S2/SvPas)	abnormal nasal capsule morphology	J:32018
	abnormal serous gland morphology	J:32018
	abnormal small intestine morphology	J:32018
	pointed snout	J:32018
	postnatal growth retardation	J:32018
	postnatal lethality, incomplete penetrance	J:32018
	short maxilla	J:32018

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24