Pax7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pax7
paired box 7
MGI:97491

33 phenotypes from 9 alleles in 12 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pax7^tm1(cre)Mrc/Pax7^tm1(cre)Mrc involves: 129S1/Sv * 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:93443
Pax7^{tm1(cre/Esr1)Cklr}/Pax7^{tm1(cre/Esr1)Cklr} involves: 129S1/Sv * 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:157754
Pax7^{tm1.1(KOMP)Vlcg}/Pax7⁺ C57BL/6N-Pax7^{tm1.1(KOMP)Vlcg}/J	decreased circulating triglyceride level	J:211773
Pax7^{tm1.1(KOMP)Vlcg}/Pax7^{tm1.1(KOMP)Vlcg} C57BL/6N-Pax7^{tm1.1(KOMP)Vlcg}/J	preweaning lethality, incomplete penetrance	J:211773
Pax7^{tm1.1(KOMP)Vlcg}/Pax7^{tm1.1(KOMP)Vlcg} C57BL/6N-Pax7^{tm1.1(KOMP)Vlcg}/Ucd	preweaning lethality, complete penetrance	J:211773
Pax7^{tm1.1(rtTA)Sjl}/Pax7^{tm1.1(rtTA)Sjl} involves: 129S1/Sv * 129X1/SvJ * C57BL/6	cachexia	J:188599
	decreased body size	J:188599
	decreased skeletal muscle weight	J:188599
	postnatal lethality, incomplete penetrance	J:188599
Pax7^tm1.1Thbr/Pax7^tm1.1Thbr Not Specified	abnormal skeletal muscle satellite cell proliferation	J:202693
Pax7^tm1.1Thbr/Pax7^tm1.1Thbr Myf5^tm1(cre)Mrc/Myf5⁺ involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ	decreased satellite cell number	J:202693
Pax7^tm1.1Thbr/Pax7^tm1.1Thbr Myf5^tm3(cre)Sor/Myf5⁺ involves: 129S4/SvJaeSor	decreased body size	J:202693
	decreased satellite cell number	J:202693
	decreased skeletal muscle fiber diameter	J:202693
	decreased skeletal muscle fiber number	J:202693
	impaired skeletal muscle regeneration	J:202693
Pax7^tm1.1Thbr/Pax7^tm1.1Thbr Tg(CMV-cre)1Cgn/0 involves: BALB/cJ	abnormal muscle morphology	J:202693
	decreased satellite cell number	J:202693
Pax7^tm1.1Thbr/Pax7^{tm2.1(cre/ERT2)Fan} involves: 129S1/Sv * 129X1/SvJ	abnormal muscle regeneration	J:202693
	abnormal skeletal muscle morphology	J:202693
	abnormal skeletal muscle satellite cell proliferation	J:202693
	decreased satellite cell number	J:202693
	decreased skeletal muscle size	J:202693
	normal muscle phenotype	J:202693
	skeletal muscle fibrosis	J:202693
	skeletal muscle necrosis	J:202693
Pax7^tm1.2Fan/Pax7^tm1.2Fan involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	impaired skeletal muscle regeneration	J:150962
	skeletal muscle fibrosis	J:150962
Pax7^tm1Pgr/Pax7^tm1Pgr involves: 129S2/SvPas	abnormal muscle regeneration	J:64793
	abnormal nasal capsule morphology	J:32018
	abnormal serous gland morphology	J:32018
	normal cellular phenotype	J:64793
	decreased skeletal muscle fiber diameter	J:64793
	normal digestive/alimentary phenotype	J:32018
	normal embryo phenotype	J:32018
	normal muscle phenotype	J:32018
	muscle weakness	J:64793
	normal nervous system phenotype	J:32018
	pointed snout	J:32018
	postnatal growth retardation	J:32018, J:64793
	postnatal lethality, incomplete penetrance	J:32018
	premature death	J:32018
	short maxilla	J:32018
	thin diaphragm muscle	J:64793
Pax7^tm2Pgr/Pax7^tm2Pgr either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: 129S2/SvPas * C57BL/6)	abnormal muscle regeneration	J:92280
	decreased satellite cell number	J:92280
Pax7^tm2Pgr/Pax7^tm2Pgr either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S2/SvPas)	abnormal nasal capsule morphology	J:32018
	abnormal serous gland morphology	J:32018
	abnormal small intestine morphology	J:32018
	pointed snout	J:32018
	postnatal growth retardation	J:32018
	postnatal lethality, incomplete penetrance	J:32018
	short maxilla	J:32018

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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