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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mapt
microtubule-associated protein tau
MGI:97180
23 phenotypes from 12 alleles in 11 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Chattm2(cre)Lowl/Chat+
Mapttm3(Sema3e)Arbr/Mapttm3(Sema3e)Arbr
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 		abnormal motor neuron innervation pattern J:149553
normal behavior/neurological phenotype J:149553
Mapttm1(EGFP)Klt/Mapttm1(EGFP)Klt
B6.129S4-Mapttm1(EGFP)Klt 		abnormal motor learning J:213115
enhanced spatial learning J:213115
impaired contextual conditioning behavior J:213115
impaired cued conditioning behavior J:213115
reduced long-term potentiation J:213115
Mapttm1(EGFP)Klt/Mapttm1(EGFP)Klt
involves: 129S4/SvJae * C57BL/6 		normal behavior/neurological phenotype J:169074
no abnormal phenotype detected J:66561
Mapttm1(Setdb1)Akba/Mapttm1(Setdb1)Akba
involves: 129S7/SvEvBrd * C57BL/6J 		normal behavior/neurological phenotype J:178512
normal mortality/aging J:178512
Mapttm1.1(MAPT)Tcs/Mapttm1.1(MAPT)Tcs
B6.Cg-Mapttm1.1(MAPT)Tcs 		normal nervous system phenotype J:278451
Mapttm1.1Cole/Mapttm1.1Cole
involves: C57BL/6J * C57BL/6JOlaHsd 		normal behavior/neurological phenotype J:188213
Mapttm1Aha/Mapttm1Aha
Not Specified 		abnormal axon morphology J:123734
Mapttm1b(EUCOMM)Hmgu/Mapttm1b(EUCOMM)Hmgu
C57BL/6N-Mapttm1b(EUCOMM)Hmgu/Ics 		abnormal retina blood vessel morphology J:211773
abnormal retina vasculature morphology J:211773
decreased exploration in new environment J:211773
decreased grip strength J:211773
decreased total retina thickness J:211773
increased fluid intake J:211773
persistence of hyaloid vascular system J:211773
polycystic kidney J:211773
Mapttm1Hnd/Mapt+
involves: 129X1/SvJ * C57BL/6 		decreased susceptibility to pharmacologically induced seizures J:121330
Mapttm1Hnd/Mapttm1Hnd
involves: 129X1/SvJ * C57BL/6 		abnormal axon extension J:78649
abnormal dendrite morphology J:78649
decreased susceptibility to pharmacologically induced seizures J:121330
Mapttm1Noh/Mapttm1Noh
involves: 129S4/SvJae 		abnormal axon morphology J:19030
Mapttm2(cre)Aha/Mapttm2(cre)Aha
Not Specified 		normal nervous system phenotype J:134499
Mapttm2Arbr/Mapt+
Pvalbtm1(cre)Arbr/Pvalb+
involves: 129P2/OlaHsd * C57BL/6 		abnormal dorsal root ganglion morphology J:100886
Mapttm3(cre/PGR)Aha/Mapttm3(cre/PGR)Aha
Not Specified 		no abnormal phenotype detected J:136624
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory