83 phenotypes from 7 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Itgb3tm1.1Wlbcr/Itgb3tm1.1Wlbcr involves: C57BL/6	no abnormal phenotype detected	J:224675
Itgb3tm1Aja/Itgb3tm1Aja involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal platelet activation	J:148306
	abnormal platelet dense granule physiology	J:148306
	abnormal platelet physiology	J:148306
	decreased susceptibility to induced thrombosis	J:148306
	increased bleeding time	J:148306
Itgb3tm1Drp/Itgb3tm1Drp Not Specified	abnormal blood coagulation	J:73416
Itgb3tm1Hyn/Itgb3+ involves: 129S2/SvPas * C57BL/6	cardiac hypertrophy	J:119666
	decreased heart rate	J:119666
	heart left ventricle hypertrophy	J:119666
	increased heart left ventricle weight	J:119666
	increased heart weight	J:119666
	increased response of heart to induced stress	J:119666
Itgb3tm1Hyn/Itgb3tm1.1Wlbcr Lyz2tm1(cre)Ifo/Lyz2+ involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6	abnormal osteoclast differentiation	J:224675
	abnormal osteoclast morphology	J:224675
	abnormal tumor pathology	J:224675
	abnormal tumor susceptibility	J:224675
	decreased collagen level	J:224675
	decreased osteoclast cell number	J:224675
	increased bone mineral density	J:224675
	increased trabecular bone volume	J:224675
	osteopetrosis	J:224675
Itgb3tm1Hyn/Itgb3tm1.1Wlbcr Tg(Pf4-icre)Q3Rsko/0 involves: 129S2/SvPas * C57BL/6	abnormal blood coagulation	J:224675
	abnormal hemostasis	J:224675
	decreased hemoglobin content	J:224675
	decreased platelet aggregation	J:224675
	enlarged spleen	J:224675
	gastrointestinal hemorrhage	J:224675
	increased bleeding time	J:224675
	intracranial hemorrhage	J:224675
	postnatal lethality, incomplete penetrance	J:224675
Itgb3tm1Hyn/Itgb3tm1Hyn involves: 129S2/SvPas	abnormal osteoclast morphology	J:60672
	abnormal osteoclast physiology	J:60672
	abnormal physiological neovascularization	J:96049
	abnormal platelet physiology	J:96049
	decreased circulating calcium level	J:60672
	decreased keratinocyte proliferation	J:96049
	decreased macrophage cell number	J:96049
	enhanced wound healing	J:96049
	increased compact bone thickness	J:60672
	increased osteoclast cell number	J:60672
	increased trabecular bone thickness	J:60672
	increased transforming growth factor beta level	J:96049
	osteosclerosis	J:60672
Itgb3tm1Hyn/Itgb3tm1Hyn involves: 129S2/SvPas * BALB/c	normal immune system phenotype	J:131241
	increased IgG level	J:131241
	increased miscarriage rate	J:131241
	maternal effect	J:131241
	pregnancy-related premature death	J:131241
Itgb3tm1Hyn/Itgb3tm1Hyn involves: 129S2/SvPas * C57BL/6	abnormal cardiac muscle relaxation	J:119666
	abnormal cell adhesion	J:73752
	abnormal cell migration	J:73752
	abnormal induced retina neovascularization	J:73752
	abnormal macrophage physiology	J:119666
	abnormal placenta labyrinth morphology	J:52262
	abnormal platelet activation	J:52262
	abnormal trophoblast giant cell morphology	J:52262
	abnormal tumor vascularization	J:73752
	abnormal uterine environment	J:52262
	anemia	J:52262
	cardiac hypertrophy	J:119666
	decreased cardiac muscle contractility	J:119666
	decreased erythrocyte cell number	J:52262
	decreased heart rate	J:119666
	decreased hematocrit	J:52262
	decreased hemoglobin content	J:52262
	decreased left ventricle systolic pressure	J:119666
	dermatitis	J:52262
	enlarged spleen	J:52262
	extramedullary hematopoiesis	J:52262
	gastrointestinal hemorrhage	J:52262
	heart left ventricle hypertrophy	J:119666
	hemorrhage	J:52262
	hepatic necrosis	J:52262
	impaired macrophage chemotaxis	J:119666
	increased angiogenesis	J:73752
	increased bleeding time	J:52262
	increased heart left ventricle weight	J:119666
	increased heart weight	J:119666
	increased left ventricle diastolic pressure	J:119666
	increased miscarriage rate	J:52262
	increased monocyte cell number	J:119666
	increased response of heart to induced stress	J:119666
	increased tumor growth/size	J:73752
	myositis	J:119666
	pale placenta	J:52262
	petechiae	J:52262
	postnatal lethality, incomplete penetrance	J:52262
	premature death	J:52262
	purpura	J:52262
	reduced female fertility	J:52262
	renal necrosis	J:52262
	reticulocytosis	J:52262
	skin hemorrhage	J:52262
	uterine hemorrhage	J:52262
	normal vision/eye phenotype	J:52262
Itgb3tm1Mgin/Itgb3tm1Mgin involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N	abnormal platelet activation	J:123968
	decreased erythrocyte cell number	J:123968
	decreased hematocrit	J:123968
	decreased hemoglobin content	J:123968
	gastrointestinal hemorrhage	J:123968
	increased bleeding time	J:123968
	increased mean corpuscular hemoglobin	J:123968
	increased mean corpuscular volume	J:123968
	perinatal lethality, incomplete penetrance	J:123968
Itgb3tm2Aja/Itgb3tm2Aja involves: 129S1/Sv * 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:148306
Itgb3tm2Mgin/Itgb3tm2Mgin involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N	abnormal platelet activation	J:123968
	abnormal thrombosis	J:129707
	decreased erythrocyte cell number	J:123968
	gastrointestinal hemorrhage	J:123968
	increased bleeding time	J:123968
	increased mean corpuscular hemoglobin	J:123968