48 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Eef1a1tm1(Kras*)Arge/Eef1a1+ Igf1rtm2Arge/Igf1r+ Waptm1(cre)Arge/Wap+ involves: 129S1/Sv	decreased tumor-free survival time	J:146290
	increased mammary gland tumor incidence	J:146290
Eef1a1tm1(Kras*)Arge/Eef1a1+ Igf1rtm2Arge/Igf1rtm2Arge Waptm1(cre)Arge/Wap+ involves: 129S1/Sv	decreased tumor-free survival time	J:146290
	increased mammary gland tumor incidence	J:146290
Gpc3tm1Arge/Gpc3tm1Arge Igf1rtm1Arge/Igf1rtm1Arge involves: 129S/SvEv * 129S1/Sv * C57BL/6J	abnormal calcaneum morphology	J:75054
	abnormal hindlimb morphology	J:75054
	perinatal lethality, complete penetrance	J:75054
Gpc3tm1Arge/Y Igf1rtm1Arge/Igf1rtm1Arge involves: 129S/SvEv * 129S1/Sv * C57BL/6J	abnormal calcaneum morphology	J:75054
	abnormal hindlimb morphology	J:75054
	perinatal lethality, complete penetrance	J:75054
Igf1tm1Arge/Igf1tm1Arge Igf1rtm1Arge/Igf1rtm1Arge either: (involves: 129S/SvEv) or (involves: 129S/SvEv * C57BL/6J) or (involves: 129S/SvEv * MF1)	decreased birth weight	J:15108
	delayed bone ossification	J:15108
	neonatal lethality, complete penetrance	J:15108
	respiratory failure	J:15108
Igf1rtm1.1Mhz/Igf1r+ Insrtm1Khn/Insrtm1Khn Tg(Ckmm-cre)5Khn/0 involves: 129/Sv * 129S4/SvJae * C57BL/6 * FVB	abnormal breathing pattern	J:118987
	decreased locomotor activity	J:118987
	decreased ventricle muscle contractility	J:118987
	normal homeostasis/metabolism phenotype	J:118987
	premature death	J:118987
Igf1rtm1.1Mhz/Igf1rtm1.1Mhz Insrtm1Khn/Insr+ Tg(Ckmm-cre)5Khn/0 involves: 129/Sv * 129S4/SvJae * C57BL/6 * FVB	normal cardiovascular system phenotype	J:118987
	normal growth/size/body region phenotype	J:118987
	normal homeostasis/metabolism phenotype	J:118987
Igf1rtm1.1Mhz/Igf1rtm1.1Mhz Insrtm1Khn/Insrtm1Khn involves: 129/Sv * 129S4/SvJae * C57BL/6 * FVB	normal cardiovascular system phenotype	J:118987
	normal growth/size/body region phenotype	J:118987
	normal homeostasis/metabolism phenotype	J:118987
Igf1rtm1.1Mhz/Igf1rtm1.1Mhz Insrtm1Khn/Insrtm1Khn Tg(Ckmm-cre)5Khn/0 involves: 129/Sv * 129S4/SvJae * C57BL/6 * FVB	abnormal breathing pattern	J:118987
	abnormal heart left ventricle morphology	J:118987
	abnormal myocardial fiber morphology	J:118987
	cardiac interstitial fibrosis	J:118987
	congestive heart failure	J:118987
	decreased body weight	J:118987
	decreased heart rate	J:118987
	decreased heart weight	J:118987
	decreased locomotor activity	J:118987
	decreased myocardial fiber size	J:118987
	decreased ventricle muscle contractility	J:118987
	dilated cardiomyopathy	J:118987
	normal homeostasis/metabolism phenotype	J:118987
	postnatal growth retardation	J:118987
	postnatal lethality, complete penetrance	J:118987
	small heart	J:118987
	thin interventricular septum	J:118987
	thin ventricular wall	J:118987
Igf1rtm1.2Mhz/Igf1r+ Zfand2btm1Otin/Zfand2btm1Otin involves: 129/Sv * 129S7/SvEvBrd * C57BL/6	normal hematopoietic system phenotype	J:233169
	normal neoplasm	J:233169
Igf1rtm1Arge/Igf1r+ Igf2rtm1Arge/Igf2r+ involves: 129/Sv * 129S/SvEv	decreased survivor rate	J:34584
	increased birth weight	J:34584
	perinatal lethality, incomplete penetrance	J:34584
Igf1rtm1Arge/Igf1r+ Igf2rtm1Arge/Igf2rtm1Arge involves: 129/Sv * 129S/SvEv	decreased survivor rate	J:34584
	increased birth weight	J:34584
	perinatal lethality, incomplete penetrance	J:34584
Igf1rtm1Arge/Igf1r+ Igf2rtm2Arge/Igf2r+ involves: 129/Sv * 129S/SvEv	decreased survivor rate	J:34584
	increased birth weight	J:34584
	perinatal lethality, incomplete penetrance	J:34584
Igf1rtm1Arge/Igf1r+ Igf2rtm2Arge/Igf2rtm2Arge involves: 129/Sv * 129S/SvEv	decreased survivor rate	J:34584
	increased birth weight	J:34584
	perinatal lethality, incomplete penetrance	J:34584
Igf1rtm1Arge/Igf1rtm1Arge Igf2tm1Rob/Igf2+ involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	small placenta	J:34584
Igf1rtm1Arge/Igf1rtm1Arge Igf2tm1Rob/Igf2+ involves: 129S/SvEv	abnormal epidermal layer morphology	J:15108
	abnormal nervous system morphology	J:15108
	decreased birth weight	J:15108
	delayed bone ossification	J:15108
	maternal imprinting	J:15108
	neonatal lethality, complete penetrance	J:15108
	respiratory failure	J:15108
Igf1rtm1Arge/Igf1rtm1Arge Igf2tm1Rob/Igf2+ Igf2rtm1Arge/Igf2r+ involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	small placenta	J:34584
Igf1rtm1Arge/Igf1rtm1Arge Igf2tm1Rob/Igf2+ Igf2rtm1Arge/Igf2rtm1Arge involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	small placenta	J:34584
Igf1rtm1Arge/Igf1rtm1Arge Igf2tm1Rob/Igf2+ Igf2rtm2Arge/Igf2r+ involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	small placenta	J:34584
Igf1rtm1Arge/Igf1rtm1Arge Igf2tm1Rob/Igf2+ Igf2rtm2Arge/Igf2rtm2Arge involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	small placenta	J:34584
Igf1rtm1Arge/Igf1rtm1Arge Igf2tm1Rob/Igf2tm1Rob involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	small placenta	J:34584
Igf1rtm1Arge/Igf1rtm1Arge Igf2tm1Rob/Igf2tm1Rob Igf2rtm1Arge/Igf2r+ involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	small placenta	J:34584
Igf1rtm1Arge/Igf1rtm1Arge Igf2tm1Rob/Igf2tm1Rob Igf2rtm1Arge/Igf2rtm1Arge involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	small placenta	J:34584
Igf1rtm1Arge/Igf1rtm1Arge Igf2tm1Rob/Igf2tm1Rob Igf2rtm2Arge/Igf2rtm2Arge involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	small placenta	J:34584
Igf1rtm1Arge/Igf1rtm1Arge Igf2rtm1Arge/Igf2r+ involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	increased birth weight	J:34584
Igf1rtm1Arge/Igf1rtm1Arge Igf2rtm1Arge/Igf2r+ involves: 129/Sv * 129S/SvEv	abnormal maternal nurturing	J:34584
	decreased birth weight	J:34584
	decreased litter size	J:34584
	enlarged placenta	J:34584
	normal growth/size/body region phenotype	J:34584
	normal mortality/aging	J:34584
	slow postnatal weight gain	J:34584
Igf1rtm1Arge/Igf1rtm1Arge Igf2rtm1Arge/Igf2r+ involves: 129/Sv * 129S/SvEv * C57BL/6J * MF1	decreased survivor rate	J:34584
	postnatal lethality, incomplete penetrance	J:34584
Igf1rtm1Arge/Igf1rtm1Arge Igf2rtm1Arge/Igf2rtm1Arge involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	increased birth weight	J:34584
Igf1rtm1Arge/Igf1rtm1Arge Igf2rtm1Arge/Igf2rtm1Arge involves: 129/Sv * 129S/SvEv	abnormal maternal nurturing	J:34584
	decreased litter size	J:34584
	enlarged placenta	J:34584
	normal growth/size/body region phenotype	J:34584
	normal mortality/aging	J:34584
	slow postnatal weight gain	J:34584
Igf1rtm1Arge/Igf1rtm1Arge Igf2rtm1Arge/Igf2rtm1Arge involves: 129/Sv * 129S/SvEv * C57BL/6J * MF1	decreased survivor rate	J:34584
	postnatal lethality, incomplete penetrance	J:34584
Igf1rtm1Arge/Igf1rtm1Arge Igf2rtm2Arge/Igf2r+ involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	increased birth weight	J:34584
Igf1rtm1Arge/Igf1rtm1Arge Igf2rtm2Arge/Igf2r+ involves: 129/Sv * 129S/SvEv	abnormal maternal nurturing	J:34584
	decreased birth weight	J:34584
	decreased litter size	J:34584
	enlarged placenta	J:34584
	normal growth/size/body region phenotype	J:34584
	normal mortality/aging	J:34584
	slow postnatal weight gain	J:34584
Igf1rtm1Arge/Igf1rtm1Arge Igf2rtm2Arge/Igf2r+ involves: 129/Sv * 129S/SvEv * C57BL/6J * MF1	decreased survivor rate	J:34584
	postnatal lethality, incomplete penetrance	J:34584
Igf1rtm1Arge/Igf1rtm1Arge Igf2rtm2Arge/Igf2rtm2Arge involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	increased birth weight	J:34584
Igf1rtm1Arge/Igf1rtm1Arge Igf2rtm2Arge/Igf2rtm2Arge involves: 129/Sv * 129S/SvEv	abnormal maternal nurturing	J:34584
	decreased litter size	J:34584
	enlarged placenta	J:34584
	normal growth/size/body region phenotype	J:34584
	normal mortality/aging	J:34584
	slow postnatal weight gain	J:34584
Igf1rtm1Arge/Igf1rtm1Arge Igf2rtm2Arge/Igf2rtm2Arge involves: 129/Sv * 129S/SvEv * C57BL/6J * MF1	decreased survivor rate	J:34584
	postnatal lethality, incomplete penetrance	J:34586
Igf1rtm1Arge/Igf1rtm1Arge Insrtm1Dac/Insr+ Insrrtm1Dac/Insrrtm1Dac involves: 129S/SvEv * 129S1/Sv * 129S4/SvJae * C57BL/6J	abnormal primary sex determination	J:86618
	primary sex reversal	J:86618
Igf1rtm1Arge/Igf1rtm1Arge Insrtm1Dac/Insrtm1Dac involves: 129S/SvEv * 129S4/SvJae * C57BL/6J	ovotestis	J:86618
	primary sex reversal	J:86618
Igf1rtm1Arge/Igf1rtm1Arge Insrtm1Dac/Insrtm1Dac Insrrtm1Dac/Insrrtm1Dac involves: 129S/SvEv * 129S1/Sv * 129S4/SvJae * C57BL/6J	abnormal primary sex determination	J:86618
	primary sex reversal	J:86618