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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Id1
inhibitor of DNA binding 1, HLH protein
MGI:96396
43 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sor+
Id1tm3Bene/Id1tm3Bene
Id2tm1Xdz/Id2tm1Xdz
Id3tm1Zhu/Id3tm1Zhu
involves: 129S4/SvJaeSor * C57BL/6
premature neuronal precursor differentiation J:185426
Id1tm1Zhu/Id1+
Id3tm1Zhu/Id3+
Twist1tm1Bhr/Twist1+
involves: 129S1/Sv * 129S4/SvJaeSor * 129S7/SvEvBrd
premature cranial suture closure J:108218
Id1tm1Zhu/Id1+
Id3tm1Zhu/Id3tm1Zhu
involves: 129S1/Sv * 129S4/SvJaeSor
abnormal middle ear morphology J:311050
abnormal tumor vascularization J:86480
conductive hearing loss J:311050
decreased distortion product otoacoustic emission amplitude J:311050
decreased metastatic potential J:86480
decreased tumor growth/size J:86480
increased or absent threshold for auditory brainstem response J:311050
increased susceptibility to otitis media J:311050
middle ear effusion J:311050
tumor regression J:86480
Id1tm1Zhu/Id1tm1Zhu
Id3tm1Zhu/Id3+
involves: 129S1/Sv * 129S4/SvJaeSor
abnormal middle ear morphology J:311050
conductive hearing loss J:311050
decreased distortion product otoacoustic emission amplitude J:311050
increased or absent threshold for auditory brainstem response J:311050
increased susceptibility to otitis media J:311050
middle ear effusion J:311050
normal vision/eye phenotype J:170418
Id1tm1Zhu/Id1tm1Zhu
Id3tm1Zhu/Id3+
Twist1tm1Bhr/Twist1+
involves: 129S1/Sv * 129S4/SvJaeSor * 129S7/SvEvBrd
normal skeleton phenotype J:108218
Id1tm1Zhu/Id1tm1Zhu
Id3tm1Zhu/Id3tm1Zhu
either: (involves: 129S1/Sv * 129S4/SvJaeSor) or (involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6)
preweaning lethality, complete penetrance J:44278
Id1tm1Zhu/Id1tm1Zhu
Id3tm1Zhu/Id3tm1Zhu
involves: 129S1/Sv * 129S4/SvJaeSor
abnormal brain vasculature morphology J:86480
abnormal embryonic/fetal subventricular zone morphology J:86480
abnormal neuronal precursor proliferation J:86480, J:170418
abnormal retina development J:170418
decreased angiogenesis J:86480
decreased brain size J:86480
decreased embryo weight J:86480
embryonic lethality during organogenesis, complete penetrance J:86480, J:170418
intracranial hemorrhage J:86480
microphthalmia J:170418
premature neuronal precursor differentiation J:86480
retina hypoplasia J:170418
small lens J:170418
Id1tm1Zhu/Id1tm1Zhu
Tcf3tm1Wein/Tcf3tm1Wein
involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6
abnormal thymus corticomedullary boundary morphology J:44278
absent B cells J:44278
arrested B cell differentiation J:44278
decreased lymphocyte cell number J:44278
increased T cell derived lymphoma incidence J:44278
intermingled spleen red and white pulp J:44278
neonatal lethality, incomplete penetrance J:44278
postnatal growth retardation J:44278
postnatal lethality, incomplete penetrance J:44278
Id1tm1Zhu/Id1tm1Zhu
Twist1tm1Bhr/Twist1+
involves: 129S1/Sv * 129S7/SvEvBrd
premature cranial suture closure J:108218
Id1tm3Bene/Id1tm3Bene
Id2tm1Xdz/Id2+
Id3tm1Zhu/Id3tm1Zhu
Tg(Nes-cre)1Kln/0
involves: 129S4/SvJaeSor * C57BL/6 * SJL
normal nervous system phenotype J:185426
Id1tm3Bene/Id1tm3Bene
Id2tm1Xdz/Id2tm1Xdz
Id3tm1Zhu/Id3tm1Zhu
Tg(Nes-cre)1Kln/0
involves: 129S4/SvJaeSor * C57BL/6 * SJL
abnormal brain morphology J:185426
abnormal cell cycle J:185426
abnormal cortical ventricular zone morphology J:185426
abnormal neuron differentiation J:185426
abnormal neuronal precursor proliferation J:185426
enlarged brain ventricles J:185426
neonatal lethality, incomplete penetrance J:185426
premature neuronal precursor differentiation J:185426
thin external granule cell layer J:185426

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory