Hmox1em1(IMPC)Mbp/Hmox1+
C57BL/6N-Hmox1em1(IMPC)Mbp/MbpMmucd
|
abnormal placenta morphology |
J:211773
|
edema |
J:211773
|
hemorrhage |
J:211773
|
microphthalmia |
J:211773
|
Hmox1em1(IMPC)Mbp/Hmox1em1(IMPC)Mbp
C57BL/6N-Hmox1em1(IMPC)Mbp/MbpMmucd
|
abnormal craniofacial morphology |
J:211773
|
abnormal facial morphology |
J:211773
|
abnormal head shape |
J:211773
|
abnormal placenta morphology |
J:211773
|
abnormal placenta size |
J:211773
|
embryonic growth retardation |
J:211773
|
preweaning lethality, complete penetrance |
J:211773
|
preweaning lethality, incomplete penetrance |
J:211773
|
Hmox1tm1.1Gkl/Hmox1tm1.1Gkl Lyz2tm1(cre)Ifo/Lyz2+
involves: 129 * 129P2/OlaHsd * BALB/cJ * C57BL/6
|
decreased interferon-beta secretion |
J:148498
|
decreased susceptibility to bacterial infection induced morbidity/mortality |
J:148498
|
decreased susceptibility to Paramyxoviridae infection |
J:148498
|
increased B cell number |
J:148498
|
increased CD4-positive, alpha-beta T cell number |
J:148498
|
increased CD8-positive, alpha-beta T cell number |
J:148498
|
increased circulating tumor necrosis factor level |
J:148498
|
increased granulocyte number |
J:148498
|
increased interferon-gamma secretion |
J:148498
|
increased macrophage cell number |
J:148498
|
increased splenocyte proliferation |
J:148498
|
increased susceptibility to experimental autoimmune encephalomyelitis |
J:148498
|
Hmox1tm1.1Hes/Hmox1tm1.1Hes Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * C57BL/6J * C57BL/6N
|
abnormal cellular respiration |
J:214639
|
abnormal metabolism |
J:214639
|
abnormal mitochondrial physiology |
J:214639
|
abnormal redox activity |
J:214639
|
decreased circulating free fatty acids level |
J:214639
|
decreased fat cell size |
J:214639
|
decreased inflammatory response |
J:214639
|
decreased interleukin-1 beta secretion |
J:214639
|
decreased interleukin-6 secretion |
J:214639
|
decreased susceptibility to diet-induced hepatic steatosis |
J:214639
|
decreased susceptibility to weight gain |
J:214639
|
decreased tumor necrosis factor secretion |
J:214639
|
improved glucose tolerance |
J:214639
|
increased energy expenditure |
J:214639
|
increased insulin sensitivity |
J:214639
|
Hmox1tm1.1Hes/Hmox1tm1.1Hes Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: C57BL/6 * C57BL/6J * C57BL/6N * DBA
|
abnormal cellular respiration |
J:214639
|
abnormal metabolism |
J:214639
|
abnormal mitochondrial physiology |
J:214639
|
abnormal redox activity |
J:214639
|
decreased circulating alanine transaminase level |
J:214639
|
decreased circulating aspartate transaminase level |
J:214639
|
decreased susceptibility to diet-induced hepatic steatosis |
J:214639
|
increased insulin sensitivity |
J:214639
|
Hmox1tm1.1Hes/Hmox1tm1.1Hes Tg(Ckmm-cre)5Khn/0
involves: C57BL/6J * C57BL/6N * FVB/N
|
normal
homeostasis/metabolism phenotype |
J:214639
|
Hmox1tm1.1Hes/Hmox1tm1.1Hes Tg(Fabp4-cre)1Rev/0
involves: C57BL/6J * C57BL/6N
|
normal
homeostasis/metabolism phenotype |
J:214639
|
Hmox1tm1.1Hes/Hmox1tm1.1Hes Tg(Ins2-cre)25Mgn/0
involves: C57BL/6 * C57BL/6J * C57BL/6N * DBA
|
normal
homeostasis/metabolism phenotype |
J:214639
|
Hmox1tm1.2Gkl/Hmox1tm1.2Gkl
involves: 129 * BALB/cJ * C57BL/6
|
enlarged spleen |
J:148498
|
increased inflammatory response |
J:148498
|
liver inflammation |
J:148498
|
postnatal lethality, incomplete penetrance |
J:148498
|
premature death |
J:148498
|
Hmox1tm1Mlee/Hmox1tm1Mlee
B6.129S2-Hmox1tm1Mlee
|
abnormal artery morphology |
J:106600
|
abnormal vascular smooth muscle physiology |
J:106600
|
increased vascular smooth muscle cell proliferation |
J:106600
|
Hmox1tm1Mlee/Hmox1tm1Mlee
involves: 129S2/SvPas * BALB/c
|
abnormal response to cardiac infarction |
J:54684
|
abnormal thrombosis |
J:54684
|
cardiac fibrosis |
J:54684
|
cerebral edema |
J:153083
|
dilated heart right ventricle |
J:54684
|
increased cardiomyocyte apoptosis |
J:54684
|
increased circulating alanine transaminase level |
J:153083
|
increased heart right ventricle weight |
J:54684
|
increased susceptibility to parasitic infection |
J:153083
|
increased susceptibility to parasitic infection induced morbidity/mortality |
J:153083
|
liver failure |
J:153083
|
myocardium necrosis |
J:54684
|
oxidative stress |
J:54684
|
perinatal lethality, incomplete penetrance |
J:54684
|
postnatal lethality, incomplete penetrance |
J:54684
|
Hmox1tm1Poss/Hmox1tm1Poss
involves: 129 * 129S2/SvPas * C57BL/6J
|
anemia |
J:282829
|
decreased macrophage cell number |
J:282829
|
prenatal lethality, incomplete penetrance |
J:282829
|
Hmox1tm1Poss/Hmox1tm1Poss
involves: 129S2/SvPas * C57BL/6
|
abnormal iron homeostasis |
J:79254
|
abnormal leukocyte cell number |
J:79254
|
abnormal lymph node cell ratio |
J:79254
|
abnormal splenic cell ratio |
J:79254
|
anisocytosis |
J:79254
|
cachexia |
J:79254
|
chronic inflammation |
J:79254
|
decreased body size |
J:79254
|
decreased circulating iron level |
J:79254
|
decreased erythrocyte cell number |
J:79254
|
decreased hematocrit |
J:79254
|
decreased hemoglobin content |
J:79254
|
decreased locomotor activity |
J:79254
|
decreased mean corpuscular volume |
J:79254
|
enlarged lymph nodes |
J:79254
|
enlarged spleen |
J:79254
|
extramedullary hematopoiesis |
J:79254
|
glomerular crescent |
J:79254
|
glomerulonephritis |
J:79254
|
glomerulosclerosis |
J:79254
|
increased blood urea nitrogen level |
J:62437
|
increased circulating ferritin level |
J:79254
|
increased renal tubule apoptosis |
J:62437
|
infertility |
J:79254
|
kidney failure |
J:62437
|
liver fibrosis |
J:79254
|
liver inflammation |
J:79254
|
lung inflammation |
J:79254
|
microcytic anemia |
J:79254
|
oxidative stress |
J:79254
|
poor grooming |
J:79254
|
postnatal lethality, incomplete penetrance |
J:79254
|
premature death |
J:79254
|
proximal convoluted tubule brush border loss |
J:62437
|
renal cast |
J:62437
|
renal tubular necrosis |
J:62437
|
small testis |
J:79254
|
spleen hyperplasia |
J:79254
|
Hmox1tm1Ysh/Hmox1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
abnormal cardiac muscle contractility |
J:95461
|
abnormal cardiovascular system physiology |
J:95461
|
increased myocardial infarct size |
J:95461
|
myocardium necrosis |
J:95461
|
Hmox1tm1Ysh/Hmox1tm1Ysh
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
prenatal lethality, complete penetrance |
J:95461
|