About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Cd8a
CD8 subunit alpha
MGI:88346
28 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
B2mtm1Unc/B2mtm1Unc
Cd4tm1Mak/Cd4tm1Mak
Cd8atm2.1(Cd4)Asin/Cd8atm2.1(Cd4)Asin
involves: 129 * C57BL/6
abnormal T cell physiology J:180236
Cd4tm1Mak/Cd4tm1Mak
Cd8atm1Mak/Cd8atm1Mak
involves: 129S2/SvPas
increased susceptibility to viral infection J:110749
Cd4tm1Mak/Cd4tm1Mak
Cd8atm1Mak/Cd8atm1Mak
involves: 129S2/SvPas * C57BL/6 * DBA/2
abnormal double-negative T cell morphology J:12572
abnormal gamma-delta T cell number J:12572
abnormal T cell differentiation J:12572
abnormal T cell number J:12572
decreased cytotoxic T cell cytolysis J:12572
decreased double-positive T cell number J:12572
increased length of allograft survival J:12572
small thymus medulla J:12572
Cd8atm1Asin/Cd8atm1Asin
involves: 129S1/Sv * 129X1/SvJ * FVB/N
abnormal double-positive T cell morphology J:126026
Cd8atm1Asin/Cd8atm1Asin
Cd8b1tm1Litt/Cd8b1tm1Litt
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
involves: 129 * FVB/N
decreased CD4-positive, alpha-beta T cell number J:126026
increased CD8-positive, alpha-beta T cell number J:126026
Cd8atm1Asin/Cd8atm1Asin
Rag2tm1Fwa/Rag2tm1Fwa
Tg(TcraH-Y,TcrbH-Y)71Vbo/?
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J
abnormal CD8-positive, alpha beta T cell morphology J:125259
Cd8atm1Asin/Cd8atm1Asin
Tg(CD2-TcraF5,CD2-TcrbF5)1Kio/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/10 * FVB/N
abnormal positive T cell selection J:126026
decreased CD4-positive, alpha-beta T cell number J:126026
increased CD8-positive, alpha-beta T cell number J:126026
Cd8atm1Asin/Cd8atm1Mak
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * FVB/N
abnormal positive T cell selection J:126026
abnormal T cell subpopulation ratio J:126026
increased CD8-positive, alpha-beta T cell number J:126026
Cd8atm1Mak/Cd8atm1Mak
Il15tm1Imx/Il15tm1Imx
X/Yaa
BXSB.Cg-Cd8atm1Mak Il15tm1Imx/Dcr
abnormal spleen B cell follicle morphology J:179430
increased anti-nuclear antigen antibody level J:179430
increased IgG1 level J:179430
increased IgG2a level J:179430
increased IgG2b level J:179430
increased monocyte cell number J:179430
increased splenocyte number J:179430
increased susceptibility to systemic lupus erythematosus J:179430
premature death J:179430
renal glomerular immunoglobulin deposits J:179430
Cd8atm1Mak/Cd8atm1Mak
Irf2tm1Mak/Irf2tm1Mak
involves: 129S2/SvPas * C57BL/6
abnormal skin condition J:66034
Cd8atm1Mak/Cd8atm1Mak
Tgfb1tm1Doe/Tgfb1tm1Doe
involves: 129S2/SvPas * C57BL/6 * CF-1
premature death J:99033
Cd8atm1Mak/Cd8atm1Mak
X/Yaa
BXSB.129S2(B6)-Cd8atm1Mak/4Dcr
increased susceptibility to systemic lupus erythematosus J:179430
premature death J:179430
Cd8atm1Mak/Cd8atm1Mak
Zbtb7bhd/Zbtb7bhd
involves: B6.129S2-Cd8atm1Mak * B6.Cg-Thpokhd
absent CD4-positive, alpha-beta T cells J:95867

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory