About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Cd44
CD44 antigen
MGI:88338
90 phenotypes from 10 alleles in 16 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Cd44M1Btlr/Cd44M1Btlr
C57BL/6J-Cd44M1Btlr
alopecia J:267484
decreased alpha-beta T cell number J:267483
decreased CD4-positive, alpha-beta T cell number J:267483
decreased CD8-positive, alpha-beta T cell number J:267483
decreased central memory CD4-positive, alpha-beta T cell number J:267483
decreased central memory CD8 positive, alpha-beta T cell number J:267483
decreased effector memory CD4-positive, alpha-beta T cell number J:267483
Cd44tm1.1Ugu/Cd44tm1.1Ugu
B6.129(Cg)-Cd44tm1.1Ugu
decreased susceptibility to experimental autoimmune encephalomyelitis J:199279
Cd44tm1.1Ugu/Cd44tm1.1Ugu
involves: 129/Sv * C57BL/6
abnormal digestive system physiology J:62867
abnormal T-helper 1 physiology J:62867
abnormal T-helper 2 physiology J:62867
normal immune system phenotype J:62867
Cd44tm1.1Ugu/Cd44tm1.1Ugu
SJL.129(Cg)-Cd44tm1.1Ugu
decreased susceptibility to experimental autoimmune encephalomyelitis J:199279
decreased T cell proliferation J:199279
Cd44tm1Hbg/Cd44tm1Hbg
B6.129-Cd44tm1Hbg
decreased mast cell histamine storage J:146846
decreased mast cell number J:146846
Cd44tm1Hbg/Cd44tm1Hbg
involves: 129S1/Sv * 129X1/SvJ
abnormal epidermal lamellar body morphology J:108938
abnormal lipid level J:108938
abnormal osteoclast differentiation J:101563
abnormal response to cardiac infarction J:131974
abnormal response to infection J:86947
decreased cholesterol level J:108938
impaired skin barrier function J:108938
impaired wound healing J:131974
increased acute inflammation J:131974
increased diameter of tibia J:101563
short tibia J:101563
thin epidermis J:108938
Cd44tm1Hbg/Cd44tm1Hbg
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal CD4-positive, alpha beta T cell morphology J:68069
abnormal CD8-positive, alpha beta T cell morphology J:68069
abnormal leukocyte migration J:68069
abnormal neutrophil physiology J:94850
choroidal neovascularization J:154560
normal hematopoietic system phenotype J:110964
Cd44tm1Mak/Cd44+
involves: 129P2/OlaHsd * C57BL/6J
abnormal leukocyte migration J:99032
Cd44tm1Mak/Cd44tm1Mak
B6.129P2-Cd44tm1Mak
abnormal circulating cytokine level J:69351
abnormal leukocyte migration J:108245
decreased activation-induced cell death of T cells J:69351
decreased myocardial infarct size J:80446
decreased sensitivity to induced cell death J:69351
decreased transforming growth factor beta level J:111216
enhanced coordination J:80446
impaired macrophage phagocytosis J:111216
impaired natural killer cell mediated cytotoxicity J:110889
increased circulating interferon-gamma level J:69351
increased circulating interleukin-2 level J:69351
increased circulating tumor necrosis factor level J:69351
increased mean systemic arterial blood pressure J:80446
increased susceptibility to induced morbidity/mortality J:69351, J:111216
liver inflammation J:69351
lung inflammation J:108245, J:111216
Cd44tm1Mak/Cd44tm1Mak
D1.129P2-Cd44tm1Mak
increased susceptibility to induced arthritis J:95275
Cd44tm1Mak/Cd44tm1Mak
involves: 129P2/OlaHsd * C57BL/6
abnormal chemokine secretion J:155691
abnormal circulating chemokine level J:155691
abnormal interleukin secretion J:155691
abnormal miniature excitatory postsynaptic currents J:128984
abnormal physiological neovascularization J:110162
abnormal vascular endothelial cell morphology J:110162
abnormal vascular endothelial cell physiology J:110162
abnormal vasculogenesis J:110162
decreased acute inflammation J:114341
decreased angiogenesis J:110162
decreased blood urea nitrogen level J:114341
decreased circulating creatinine level J:114341
decreased circulating tumor necrosis factor level J:155691
decreased miniature excitatory postsynaptic current frequency J:128984
decreased susceptibility to kidney reperfusion injury J:114341
decreased tumor growth/size J:110162
delayed wound healing J:110162
increased interleukin-1 beta secretion J:155691
increased interleukin-6 secretion J:155691
increased interleukin-10 secretion J:155691
increased miniature excitatory postsynaptic current amplitude J:128984
increased tumor necrosis factor secretion J:155691
peritoneal inflammation J:155691
Cd44tm1Mak/Cd44tm1Mak
involves: 129P2/OlaHsd * C57BL/6J
abnormal cell morphology J:105319
abnormal cell physiology J:72658
abnormal definitive hematopoiesis J:72658
abnormal leukocyte migration J:99032
abnormal mitochondrial crista morphology J:105319
abnormal vascular smooth muscle physiology J:101783
decreased fibroblast proliferation J:105319
normal immune system phenotype J:72658
increased mitochondrial size J:105319
increased susceptibility to parasitic infection J:72658
Cd44tm1Stpa/Cd44tm1Stpa
B6.Cg-Cd44tm1Stpa
normal digestive/alimentary phenotype J:204874
Cd44tm1Ugu/Cd44tm1Ugu
involves: 129/Sv * C57BL/6
abnormal digestive system physiology J:62867
abnormal T-helper 1 physiology J:62867
abnormal T-helper 2 physiology J:62867
normal immune system phenotype J:62867
Cd44tm2.1Ugu/Cd44tm2.1Ugu
B6.129-Cd44tm2.1Ugu
decreased susceptibility to experimental autoimmune encephalomyelitis J:199279
decreased T cell proliferation J:199279
Cd44tm2Kmz/Cd44tm2Kmz
DBA/1LacJ-Cd44tm2Kmz
abnormal involution of the mammary gland J:74524
abnormal uterus morphology J:74524
decreased susceptibility to induced arthritis J:74268
Cd44tm2Kmz/Cd44tm2Kmz
involves: BALB/c * DBA/1
abnormal CD4-positive, alpha-beta T cell physiology J:114317
abnormal leukocyte adhesion J:114317
decreased susceptibility to type IV hypersensitivity reaction J:114317
impaired leukocyte tethering or rolling J:114317
impaired neutrophil recruitment J:114317
Cd44tm2Stpa/Cd44tm2Stpa
B6.Cg-Cd44tm2Stpa
normal digestive/alimentary phenotype J:204874
Cd44tm2Ugu/Cd44tm2Ugu
involves: 129S1/Sv * 129X1/SvJ
no abnormal phenotype detected J:108416

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/30/2024
MGI 6.23
The Jackson Laboratory