Cd44^tm2Ugu
Targeted Allele Detail

Summary

• Symbol: Cd44^tm2Ugu
• Name: CD44 antigen; targeted mutation 2, Ursula Gunthert
• MGI ID: MGI:3588663
• Synonyms: CD44v10-loxP
• Gene: Cd44 Location: Chr2:102641486-102732010 bp, - strand Genetic Position: Chr2, 54.13 cM
• Alliance: Cd44^tm2Ugu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:100298
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted 5' to exon v10 and a second loxP site was placed 3' to a neomycin cassette located 3' of exon v10. (J:108416)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd44 Mutation: 67 strains or lines available

References

• Original: J:100298 Spitz F, et al., Inversion-induced disruption of the Hoxd cluster leads to the partition of regulatory landscapes. Nat Genet. 2005 Aug;37(8):889-93
• All: 3 reference(s)