87 phenotypes from 10 alleles in 16 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nfatc1tm1(cre)Bz/Nfatc1+ Smarca4tm1.2Pcn/Smarca4tm1.2Pcn involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ	abnormal aortic valve morphology	J:226941
	abnormal heart ventricle morphology	J:226941
	bicuspid aortic valve	J:226941
	cardiomyopathy	J:226941
	enlarged heart	J:226941
	normal mortality/aging	J:226941
	thick aortic valve cusps	J:226941
	thick pulmonary valve	J:226941
Nfatc1tm1.1(cre)Bz/Nfatc1+ Smarca4tm1.2Pcn/Smarca4tm1.2Pcn involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ	abnormal aortic sinus morphology	J:226941
	abnormal aortic valve cusp morphology	J:226941
	abnormal aortic valve morphology	J:226941
	abnormal cardiac outflow tract development	J:226941
	abnormal coronary artery morphology	J:226941
	abnormal coronary vein morphology	J:226941
	abnormal pulmonary valve cusp morphology	J:226941
	abnormal semilunar valve morphology	J:226941
	bicuspid aortic valve	J:226941
	enlarged heart	J:226941
	lethality throughout fetal growth and development, incomplete penetrance	J:226941
	perimembraneous ventricular septal defect	J:226941
	perinatal lethality	J:226941
	thick aortic valve	J:226941
	thick heart valve cusps	J:226941
	thick myocardium	J:226941
	thick pulmonary valve	J:226941
Smarca4b2b508.1Clo/Smarca4b2b508.1Clo C57BL/6J-Smarca4b2b508.1Clo	anophthalmia	J:175213
	atrioventricular septal defect	J:175213
	complete atrioventricular septal defect	J:175213
	double outlet right ventricle	J:175213
	microcephaly	J:175213
	micrognathia	J:175213
	ventricular septal defect	J:175213
Smarca4b2b692Clo/Smarca4b2b692Clo C57BL/6J-Smarca4b2b692Clo	coronary-cameral fistula to heart right ventricle	J:175213
	double outlet right ventricle	J:175213
	muscular ventricular septal defect	J:175213
	overriding aortic valve	J:175213
	perimembraneous ventricular septal defect	J:175213
Smarca4enu1/Smarca4tm1Mag involves: 129S/Sv * C57BL/10 * CBA/Cbi	abnormal blood cell morphology/development	J:103896
	abnormal erythrocyte morphology	J:103896
	abnormal liver morphology	J:103896
	embryonic lethality during organogenesis, complete penetrance	J:103896
Smarca4mos6/Smarca4mos6 involves: BALB/cJ * C57BL/6J	embryonic lethality, complete penetrance	J:241206
Smarca4tm1.1Axvi/Smarca4tm1.1Axvi involves: 129S6/SvEvTac	no abnormal phenotype detected	J:212226
Smarca4tm1.1Grc/Smarca4tm1.1Grc involves: 129 * C57BL/6	no abnormal phenotype detected	J:101977
Smarca4tm1.1Pcn/Smarca4+ involves: 129S2/SvPas * C57BL/6 * DBA/2	cyanosis	J:172661
	patent ductus arteriosus	J:172661
	ventricular septal defect	J:172661
Smarca4tm1.2Pcn/Smarca4tm1.1Pcn Tg(Myh11-cre,-EGFP)2Mik/0 involves: 129S2/SvPas * C57BL/6 * DBA/2	abnormal intestinal smooth muscle morphology	J:172661
	abnormal jejunum morphology	J:172661
	abnormal muscle physiology	J:172661
	abnormal pulmonary circulation	J:172661
	abnormal small intestine morphology	J:172661
	congestive heart failure	J:172661
	cyanosis	J:172661
	decreased colon length	J:172661
	decreased small intestine length	J:172661
	dilated heart	J:172661
	enlarged cecum	J:172661
	enlarged ileum	J:172661
	impaired smooth muscle contractility	J:172661
	megacolon	J:172661
	patent ductus arteriosus	J:172661
	postnatal lethality, incomplete penetrance	J:172661
	primary atelectasis	J:172661
	pulmonary alveolar proteinosis	J:172661
	ventricular septal defect	J:172661
Smarca4tm1.2Pcn/Smarca4tm1.2Pcn Tg(KRT14-cre)1Ipc/? involves: 129S2/SvPas * C57BL/6 * SJL	abnormal apical ectodermal ridge morphology	J:101729
	abnormal digit morphology	J:101729
	abnormal epidermis stratum corneum morphology	J:101729
	abnormal hindlimb morphology	J:101729
	abnormal hindlimb zeugopod morphology	J:101729
	abnormal skin morphology	J:101729
	dry skin	J:101729
	impaired skin barrier function	J:101729
	monodactyly	J:101729
	neonatal lethality, complete penetrance	J:101729
	shiny skin	J:101729
Smarca4tm1.2Pcn/Smarca4tm1.2Pcn Tg(KRT14-cre/ERT2)1Ipc/? involves: 129S2/SvPas	abnormal digit morphology	J:101729
	abnormal epidermis stratum corneum morphology	J:101729
	abnormal hindlimb morphology	J:101729
	abnormal skin morphology	J:101729
	impaired skin barrier function	J:101729
Smarca4tm1.2Pcn/Smarca4tm1.2Pcn Tg(Lck-cre)1Cwi/0 Not Specified	abnormal T cell morphology	J:144072
	decreased double-negative T cell number	J:144072
Smarca4tm1.2Pcn/Smarca4tm1.2Pcn Tg(Nfat1c-cre)1Bz/0 involves: 129S2/SvPas	normal cardiovascular system phenotype	J:226941
Smarca4tm1.2Pcn/Smarca4tm1.2Pcn Tg(Sox10-cre)1Wdr/0 involves: 129S2/SvPas * C57BL/6 * CBA	abnormal melanoblast morphology	J:241206
Smarca4tm1.2Pcn/Smarca4tm1.2Pcn Tg(Tek-cre)1Ywa/0 involves: 129S2/SvPas * C57BL/6 * SJL	abnormal atrioventricular cushion morphology	J:226941
	abnormal cardiac outflow tract development	J:226941
Smarca4tm1.2Pcn/Smarca4tm1Mag Tg(Lck-cre)1Cwi/? involves: 129S/Sv * C57BL/6 * DBA/2	abnormal T cell differentiation	J:85191
	absent CD8-positive, alpha-beta T cells	J:85191
	arrested T cell differentiation	J:85191
	decreased CD4-positive, alpha-beta T cell number	J:85191
	decreased double-negative T cell number	J:85191
	decreased double-positive T cell number	J:85191
	thymus hypoplasia	J:85191
Smarca4tm1.2Pcn/Smarca4tm1Tich Tg(Lck-cre)1Cwi/0 involves: 129	abnormal T cell morphology	J:144072
	decreased double-negative T cell number	J:144072
	decreased thymocyte number	J:144072
Smarca4tm1Mag/Smarca4+ involves: 129S/Sv * C57BL/6J * CD-1	increased mammary adenocarcinoma incidence	J:132091
	increased osteosarcoma incidence	J:132091
Smarca4tm1Mag/Smarca4+ involves: 129S/Sv * CD-1	decreased survivor rate	J:66861
	exencephaly	J:66861
	increased tumor incidence	J:66861
	postnatal lethality, incomplete penetrance	J:66861
Smarca4tm1Mag/Smarca4tm1.2Pcn involves: 129S2/SvPas	normal cellular phenotype	J:66861
Smarca4tm1Mag/Smarca4tm1Mag involves: 129S/Sv * CD-1	embryonic lethality before implantation, complete penetrance	J:66861
Smarca4tm1Tich/Smarca4+ involves: 129	normal immune system phenotype	J:144072
Smarca4tm1Tich/Smarca4+ Tg(Lck-cre)1Cwi/0 involves: 129	decreased double-negative T cell number	J:144072
	decreased double-positive T cell number	J:144072
	decreased single-positive T cell number	J:144072
	decreased thymocyte number	J:144072