103 phenotypes from 3 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Agtr2tm1a(EUCOMM)Wtsi/Agtr2tm1a(EUCOMM)Wtsi B6JTyr;B6N-Agtr2tm1a(EUCOMM)Wtsi/Wtsi	decreased body weight	J:175295
	decreased circulating alanine transaminase level	J:175295
	decreased circulating LDL cholesterol level	J:175295
Agtr2tm1Gsb/Y FVB.129-Agtr2tm1Gsb	abnormal response to cardiac infarction	J:103066
	abnormal systemic arterial blood pressure	J:103237
	abnormal vascular smooth muscle morphology	J:103237
	abnormal vasculogenesis	J:103237
	abnormal vasoconstriction	J:103237
	dilated heart left ventricle	J:103066
	increased susceptibility to induced morbidity/mortality	J:103066
	increased vasoconstriction	J:103376
	vascular smooth muscle hypertrophy	J:103376
Agtr2tm1Gsb/Y involves: 129S1/Sv * 129X1/SvJ	increased susceptibility to injury	J:100334
Agtr2tm1Gsb/Y involves: 129S1/Sv * 129X1/SvJ * FVB/N	abnormal fluid intake	J:29456
	abnormal systemic arterial blood pressure	J:29456
	decreased locomotor activity	J:29456
	increased fluid intake	J:107851
	increased systemic arterial systolic blood pressure	J:107851
Agtr2tm1Gsb/Agtr2tm1Gsb involves: 129S1/Sv * 129X1/SvJ	increased susceptibility to injury	J:100334
Agtr2tm1Tin/Y B6.129P2-Agtr2tm1Tin	abnormal heart left ventricle morphology	J:146723
	abnormal myocardial fiber morphology	J:63751
	abnormal response to cardiac infarction	J:146723
	cardiac fibrosis	J:63751, J:146723
	decreased heart left ventricle posterior wall thickness	J:63751
	decreased heart left ventricle weight	J:146723
	decreased response of heart to induced stress	J:63751
	increased susceptibility to induced morbidity/mortality	J:146723
	thin interventricular septum	J:63751
Agtr2tm1Tin/Y involves: 129P2/OlaHsd	abnormal amygdala morphology	J:102774
	abnormal baroreceptor physiology	J:103144
	abnormal circulating insulin level	J:105210
	abnormal circulating leptin level	J:105210
	abnormal eating behavior	J:105210
	abnormal epididymal fat pad morphology	J:105210
	abnormal glucose homeostasis	J:105210
	abnormal habenula morphology	J:102774
	abnormal hippocampus CA1 region morphology	J:102774
	abnormal hippocampus CA2 region morphology	J:102774
	abnormal hippocampus CA3 region morphology	J:102774
	abnormal kidney cortex morphology	J:48005
	abnormal lipid homeostasis	J:105210
	abnormal piriform cortex morphology	J:102774
	abnormal respiratory quotient	J:105210
	abnormal response/metabolism to endogenous compounds	J:105210
	abnormal skeletal muscle triglyceride level	J:105210
	abnormal systemic arterial blood pressure	J:105210
	abnormal thalamus morphology	J:102774
	abnormal urine homeostasis	J:60075
	abnormal urine sodium level	J:60075
	decreased angiogenesis	J:118914
	decreased kidney apoptosis	J:48005
	decreased renal plasma flow rate	J:60075
	decreased susceptibility to diet-induced obesity	J:105210
	decreased susceptibility to weight gain	J:105210
	decreased white fat cell size	J:105210
	increased angiogenesis	J:118914
	increased energy expenditure	J:105210
	increased insulin sensitivity	J:105210
	increased mean systemic arterial blood pressure	J:103144
	increased physiological sensitivity to xenobiotic	J:103144
	increased renal vascular resistance	J:60075
	increased systemic arterial blood pressure	J:103144
	increased white fat cell number	J:105210
	renal interstitial fibrosis	J:48005
Agtr2tm1Tin/Y involves: 129P2/OlaHsd * C57BL/6	abnormal aldosterone level	J:102984
	abnormal bone trabecula morphology	J:147915
	abnormal corticosterone level	J:102984
	abnormal heart rate	J:137944
	abnormal kidney development	J:52542
	abnormal kidney morphology	J:52542
	abnormal pancreas morphology	J:146326
	abnormal renal/urinary system morphology	J:52542
	abnormal renal/urinary system physiology	J:52542
	abnormal response/metabolism to endogenous compounds	J:137944
	abnormal ureter development	J:52542
	abnormal ureter morphology	J:52542
	absent kidney	J:52542
	decreased body temperature	J:29457
	decreased exploration in new environment	J:29457
	decreased heart weight	J:137944
	decreased kidney weight	J:137944
	decreased pancreas weight	J:146326
	decreased startle reflex	J:29457
	double ureter	J:52542
	ectopic kidney	J:52542
	hydronephrosis	J:52542
	hydroureter	J:52542
	hypoalgesia	J:29457
	increased adrenaline level	J:102984
	increased bone trabecula number	J:147915
	increased bone volume	J:147915
	increased circulating adrenocorticotropin level	J:102984
	increased circulating corticosterone level	J:102984
	increased fear-related response	J:29457
	increased mean systemic arterial blood pressure	J:137944
	increased noradrenaline level	J:102984
	increased physiological sensitivity to xenobiotic	J:146326
	increased systemic arterial blood pressure	J:29457
	increased systemic arterial diastolic blood pressure	J:29457
	increased systemic arterial systolic blood pressure	J:29457
	increased trabecular bone connectivity density	J:147915
	increased trabecular bone thickness	J:147915
	large ureter	J:52542
	pancreas fibrosis	J:146326
	pancreatic acinar cell atrophy	J:146326
	polycystic kidney	J:52542
	renal hypoplasia	J:52542
	ureteropelvic junction atresia	J:52542
	ureteropelvic junction stenosis	J:52542
	ureterovesical junction obstruction	J:52542
Agtr2tm1Tin/Y SWR.129P2-Agtr2tm1Tin	decreased incidence of tumors by chemical induction	J:101726
Agtr2tm1Tin/Agtr2tm1Tin involves: 129P2/OlaHsd	abnormal urine homeostasis	J:60075
	abnormal urine sodium level	J:60075
	decreased renal plasma flow rate	J:60075
	increased renal vascular resistance	J:60075
Agtr2tm1Tin/Agtr2tm1Tin involves: 129P2/OlaHsd * C57BL/6	abnormal aldosterone level	J:102984
	abnormal corticosterone level	J:102984
	abnormal heart rate	J:137944
	abnormal kidney development	J:52542
	abnormal kidney morphology	J:52542
	abnormal pancreas morphology	J:146326
	abnormal renal/urinary system morphology	J:52542
	abnormal renal/urinary system physiology	J:52542
	abnormal response/metabolism to endogenous compounds	J:137944
	abnormal ureter development	J:52542
	absent kidney	J:52542
	decreased heart weight	J:137944
	decreased kidney weight	J:137944
	decreased pancreas weight	J:146326
	dilated ureter	J:52542
	double ureter	J:52542
	ectopic kidney	J:52542
	hydronephrosis	J:52542
	hydroureter	J:52542
	increased adrenaline level	J:102984
	increased circulating adrenocorticotropin level	J:102984
	increased circulating corticosterone level	J:102984
	increased mean systemic arterial blood pressure	J:137944
	increased noradrenaline level	J:102984
	increased physiological sensitivity to xenobiotic	J:146326
	large ureter	J:52542
	pancreas fibrosis	J:146326
	pancreatic acinar cell atrophy	J:146326
	polycystic kidney	J:52542
	renal hypoplasia	J:52542
	ureteropelvic junction atresia	J:52542
	ureteropelvic junction stenosis	J:52542
	ureterovesical junction obstruction	J:52542
	vesicoureteral reflux	J:52542