Slc17a8 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slc17a8
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8
MGI:3039629

34 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Slc17a8^em1(IMPC)Mbp/Slc17a8^em1(IMPC)Mbp C57BL/6N-Slc17a8^em1(IMPC)Mbp/MbpMmucd	abnormal adrenal gland morphology	J:211773
	abnormal auditory brainstem response	J:211773
	abnormal colon morphology	J:211773
	abnormal eye morphology	J:211773
	abnormal kidney morphology	J:211773
	abnormal lymph node morphology	J:211773
	abnormal startle reflex	J:211773
	abnormal uterus morphology	J:211773
	cataract	J:211773
	decreased exploration in new environment	J:211773
	decreased prepulse inhibition	J:211773
	decreased startle reflex	J:211773
	enlarged lymph nodes	J:211773
	enlarged uterus	J:211773
Slc17a8^tm1Edw/Slc17a8⁺ involves: 129P2/OlaHsd * C57BL/6	abnormal brain wave pattern	J:132704
Slc17a8^tm1Edw/Slc17a8^tm1Edw involves: 129P2/OlaHsd * C57BL/6	abnormal brain wave pattern	J:132704
	abnormal inner hair cell synaptic ribbon morphology	J:132704
	absent startle reflex	J:132704
	cochlear ganglion degeneration	J:132704
	deafness	J:132704
	decreased synaptic glutamate release	J:132704
	increased or absent threshold for auditory brainstem response	J:132704
	nonconvulsive seizures	J:132704
	sensorineural hearing loss	J:132704
Slc17a8^tm1Selm/Slc17a8^tm1Selm involves: 129/Sv * C57BL/6	abnormal auditory brainstem response	J:139493
	abnormal cochlear ganglion morphology	J:139493
	abnormal cochlear IHC efferent innervation pattern	J:139493
	abnormal cochlear inner hair cell physiology	J:139493
	abnormal inner hair cell synaptic ribbon morphology	J:139493
	abnormal neurotransmitter uptake	J:135586
	abnormal synaptic acetylcholine release	J:135586
	absent cochlear nerve compound action potential	J:139493
	deafness	J:139493
	decreased cochlear inner hair cell number	J:139493
	enhanced behavioral response to cocaine	J:135586
	normal hearing/vestibular/ear phenotype	J:139493
	impaired behavioral response to xenobiotic	J:135586
	increased locomotor activity	J:135586
	increased or absent threshold for auditory brainstem response	J:139493

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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