Dis3l2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dis3l2
DIS3 like 3'-5' exoribonuclease 2
MGI:2442555

20 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dis3l2^em1(IMPC)Bay/Dis3l2⁺ C57BL/6N-Dis3l2^em1(IMPC)Bay/BayMmucd	increased body length	J:211773
Dis3l2^em1(IMPC)Bay/Dis3l2^em1(IMPC)Bay C57BL/6N-Dis3l2^em1(IMPC)Bay/BayMmucd	abnormal embryo size	J:211773
	abnormal tail morphology	J:211773
	hemorrhage	J:211773
	preweaning lethality, complete penetrance	J:211773
Dis3l2^em1Dean/Dis3l2^em1Dean Tg(Zp3-cre)93Knw/0 involves: C57BL/6 * C57BL/6J * DBA/2	abnormal female meiosis	J:337555
	abnormal oocyte morphology	J:337555
	abnormal translation	J:337555
	female infertility	J:337555
	normal reproductive system phenotype	J:337555
Dis3l2^em1Jtm/Dis3l2^em1Jtm C57BL/6J-Dis3l2^em1Jtm	abnormal renal/urinary system morphology	J:272435
	abnormal spine curvature	J:272435
	bradykinesia	J:272435
	distended urinary bladder	J:272435
	normal growth/size/body region phenotype	J:272435
	hydronephrosis	J:272435
	hydroureter	J:272435
	perinatal lethality, complete penetrance	J:272435
	respiratory failure	J:272435
Dis3l2^em2Jtm/Dis3l2^em2Jtm Wt1^{tm1(EGFP/cre)Wtp}/Wt1⁺ involves: 129S4/SvJae * C57BL/6J	normal renal/urinary system phenotype	J:272435
Dis3l2^em3Jtm/Dis3l2^em3Jtm C57BL/6J-Dis3l2^em3Jtm	abnormal renal/urinary system morphology	J:272435
	abnormal spine curvature	J:272435
	bradykinesia	J:272435
	distended urinary bladder	J:272435
	normal growth/size/body region phenotype	J:272435
	hydronephrosis	J:272435
	hydroureter	J:272435
	perinatal lethality, complete penetrance	J:272435
	respiratory failure	J:272435

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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