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C57BL/6J-Dis3l2em1Jtm Strain Detail
Summary
  • Strain Name
    C57BL/6J-Dis3l2em1Jtm
  • Attributes
    coisogenic, endonuclease-mediated mutation, mutant strain
  • MGI ID
    MGI:6286055
Associated
Mutations,
Markers,
and QTL
1 associated mutation
Mutation Carried Marker
Dis3l2em1Jtm Dis3l2
Associated
Phenotypes
and
Diseases
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
normal phenotype
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Human Diseases

model 1
Perlman syndrome √
Key √ disease model expected model not found
References
  • Earliest
    J:272435 Hunter RW, et al., Loss of Dis3l2 partially phenocopies Perlman syndrome in mice and results in up-regulation of Igf2 in nephron progenitor cells. Genes Dev. 2018 Jul 1;32(13-14):903-908
  • All
    1
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory