75 phenotypes from 10 alleles in 16 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lrp4dan/Lrp4dan 129S2/SvPas-Lrp4dan	abnormal coat appearance	J:108168
	abnormal nursing	J:108168
	brachydactyly	J:108168
	normal craniofacial phenotype	J:108168
	decreased body size	J:108168
	deformed nails	J:108168
	hunched posture	J:108168
	polydactyly	J:108168
	polysyndactyly	J:108168
	syndactyly	J:108168
Lrp4mdig-2J/Lrp4mdig-2J involves: C3H/HeSnJ * SB/LeJ	abnormal tail morphology	J:165544
	oligodactyly	J:165544
	supernumerary incisors	J:165544
Lrp4mdig-3J/Lrp4mdig-3J B6.Cg-Lrp4mdig-3J/GrsrJ	abnormal digit morphology	J:224655
	abnormal spine curvature	J:224655
	abnormal tooth morphology	J:224655
	brachydactyly	J:224655
	decreased body size	J:224655
	fused phalanges	J:224655
	reduced fertility	J:224655
Lrp4mdig/Lrp4mdig DBA/1LacJ-Lrp4mdig/GrsrJ	brachydactyly	J:83757
	syndactyly	J:83757
Lrp4mdig/Lrp4mdig involves: 129S2/SvPas * DBA/1LacJ	abnormal nursing	J:108168
	brachydactyly	J:108168
	normal craniofacial phenotype	J:108168
	deformed nails	J:108168
	polydactyly	J:108168
	polysyndactyly	J:108168
	syndactyly	J:108168
Lrp4mitt/Lrp4mitt involves: C57BL/6	abnormal apical ectodermal ridge morphology	J:119654
	abnormal digit morphology	J:119654
	abnormal hair follicle development	J:119654
	abnormal mammary gland bud morphology	J:119654
	abnormal motor neuron morphology	J:188352
	abnormal neuromuscular synapse morphology	J:119654
	abnormal phrenic nerve morphology	J:119654
	abnormal tooth development	J:119654
	abnormal vibrissa morphology	J:119654
	absent kidney	J:119654
	atelectasis	J:119654
	brachypodia	J:119654
	cyanosis	J:119654
	ectopic digits	J:119654
	failure of neuromuscular synapse postsynaptic differentiation	J:119654
	failure of neuromuscular synapse presynaptic differentiation	J:119654
	fused metacarpal bones	J:119654
	fused metatarsal bones	J:119654
	neonatal lethality, complete penetrance	J:119654
	no spontaneous movement	J:119654
	oligodactyly	J:119654
	respiratory failure	J:119654
	single kidney	J:119654
	small lung	J:119654
	syndactyly	J:119654
Lrp4mte/Lrp4mte involves: C57BL/6	abnormal apical ectodermal ridge morphology	J:119654
	abnormal digit morphology	J:119654
	abnormal hair follicle development	J:119654
	abnormal mammary gland bud morphology	J:119654
	abnormal neuromuscular synapse morphology	J:119654
	abnormal phrenic nerve morphology	J:119654
	abnormal tooth development	J:119654
	abnormal vibrissa morphology	J:119654
	absent kidney	J:119654
	atelectasis	J:119654
	brachypodia	J:119654
	cyanosis	J:119654
	ectopic digits	J:119654
	failure of neuromuscular synapse postsynaptic differentiation	J:119654
	failure of neuromuscular synapse presynaptic differentiation	J:119654
	fused metacarpal bones	J:119654
	fused metatarsal bones	J:119654
	neonatal lethality, complete penetrance	J:119654
	no spontaneous movement	J:119654
	oligodactyly	J:119654
	respiratory failure	J:119654
	single kidney	J:119654
	small lung	J:119654
	syndactyly	J:119654
Lrp4tm1.1Line/Lrp4tm1.1Line Mnx1tm4(cre)Tmj/Mnx1+ involves: 129S/SvEv * 129S1/Sv * C57BL/6 * SJL	normal nervous system phenotype	J:188352
Lrp4tm1.1Line/Lrp4tm1.1Line Mnx1tm4(cre)Tmj/Mnx1+ Tg(ACTA1-cre)79Jme/0 involves: 129S/SvEv * 129S1/Sv * C57BL/6 * C57BL/6J * SJL	abnormal motor neuron morphology	J:188352
	abnormal neuromuscular synapse morphology	J:188352
	cyanosis	J:188352
	neonatal lethality, complete penetrance	J:188352
Lrp4tm1.1Line/Lrp4tm1.1Line Tg(ACTA1-cre)79Jme/0 involves: 129S/SvEv * C57BL/6 * C57BL/6J * SJL	abnormal endplate potential	J:188352
	abnormal miniature endplate potential	J:188352
	abnormal motor neuron morphology	J:188352
	abnormal neuromuscular synapse morphology	J:188352
	postnatal lethality, incomplete penetrance	J:188352
Lrp4tm1.1Pg/Lrp4+ involves: C57BL/6N	increased bone strength	J:277372
Lrp4tm1.1Pg/Lrp4tm1.1Pg involves: C57BL/6N	abnormal blood homeostasis	J:277372
	abnormal osteocyte morphology	J:277372
	decreased bone trabecular spacing	J:277372
	increased bone ossification	J:277372
	increased bone strength	J:277372
	increased bone trabecula number	J:277372
	increased diameter of femur	J:277372
	increased femur compact bone thickness	J:277372
	increased trabecular bone connectivity density	J:277372
	increased trabecular bone thickness	J:277372
	increased trabecular bone volume	J:277372
	normal muscle phenotype	J:277372
	normal renal/urinary system phenotype	J:277372
	normal skeleton phenotype	J:277372
	thick neurocranium	J:277372
Lrp4tm1Her/Lrp4tm1Her involves: 129S6/SvEvTac	abnormal enamel morphology	J:156471
	abnormal incisor morphology	J:156471
	supernumerary incisors	J:156471
Lrp4tm1Her/Lrp4tm1Her involves: 129S6/SvEvTac * C57BL/6	abnormal chondrocyte morphology	J:106811
	abnormal digit morphology	J:106811
	abnormal forelimb morphology	J:106811
	abnormal hindlimb morphology	J:106811
	abnormal incisor morphology	J:106811
	abnormal postnatal growth	J:106811
	polydactyly	J:106811
	preweaning lethality, incomplete penetrance	J:106811
	thick apical ectodermal ridge	J:106811
Lrp4tm1Her/Lrp4tm1Her involves: 129S/SvEvBrd * 129S6/SvEvTac * C57BL/6J	abnormal neuromuscular synapse morphology	J:207796
Lrp4tm2Her/Lrp4tm2Her involves: 129S/SvEv	abnormal incisor morphology	J:156471
	abnormal molar cusp morphology	J:156471
	supernumerary incisors	J:156471
Lrp4tm2Her/Lrp4tm2Her involves: 129S/SvEv * C57BL	abnormal kidney development	J:160547
	abnormal neuromuscular synapse morphology	J:160547
	abnormal ureteric bud invasion	J:160547
	abnormal ureteric bud morphology	J:160547
	absent kidney	J:160547
	absent metanephric mesenchyme	J:160547
	impaired branching involved in ureteric bud morphogenesis	J:160547
	neonatal lethality, complete penetrance	J:160547
	single kidney	J:160547
	ureter hypoplasia	J:160547
Lrp4tm2Her/Lrp4tm2Her involves: 129S/SvEvBrd * C57BL/6J	abnormal neuromuscular synapse morphology	J:207796
	failure of neuromuscular synapse postsynaptic differentiation	J:207796
	failure of neuromuscular synapse presynaptic differentiation	J:207796
	perinatal lethality, complete penetrance	J:207796