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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Hps6
HPS6, biogenesis of lysosomal organelles complex 2 subunit 3
MGI:2181763
21 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
a/a
Hps6ru-5J/Hps6ru-5J
Lystbg/Lystbg
involves: C3H/Rl * C57BL/6J
abnormal coat/hair pigmentation J:26546
abnormal eye pigmentation J:26546
decreased eye pigmentation J:26546
diluted coat color J:26546
a/a
Hps6ru/Hps6ru
B6.Cg-Hps6ru
abnormal coat/hair pigmentation J:6064
abnormal kidney physiology J:6422
abnormal lateral geniculate nucleus morphology J:6064
abnormal retina ganglion cell morphology J:6064
decreased platelet ADP level J:7327
decreased platelet ATP level J:7327
decreased platelet dense granule number J:7327
decreased platelet serotonin level J:7327, J:29748
decreased susceptibility to atherosclerosis J:29748
increased bleeding time J:7327
a/a
Hps6ru/Hps6ru
involves: C57BL/6J
abnormal eye pigmentation J:5346
abnormal melanogenesis J:5346
abnormal melanosome morphology J:5346
a/a
Hps6ru/Hps6ru
Not Specified
abnormal choroid pigmentation J:81444
abnormal eye pigmentation J:13122, J:81444
abnormal iris pigmentation J:13122
decreased eye pigmentation J:13122
diluted coat color J:13122
hypopigmentation J:12970
A/A
Hps6ru/Hps6ru
Not Specified
diluted coat color J:13122
a/a
Hps6ru/Hps6ru
Lystbg/Lystbg
involves: C3H/Rl * C57BL/6J
abnormal melanogenesis J:5346
abnormal melanosome morphology J:5346
abnormal retina melanin granule morphology J:5346
a/a
Mregdsu/Mregdsu
Hps6ru/Hps6ru
involves: C57BL/6J
diluted coat color J:29467
phenotypic reversion J:29467
Espnje/?
f/f
Hps6ru/Hps6ru
JE/LeJ
abnormal mast cell degranulation J:37255
Hps6ru/Hps6ru
Lystbg-slt/Lystbg-slt
involves: YZ57/Ch
decreased eye pigmentation J:25388
diluted coat color J:25388

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory