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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Kremen1
kringle containing transmembrane protein 1
MGI:1933988
15 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
\Dkk1tm1Lmgd/\Dkk1+
\Kremen1tm1Dgen/\Kremen1tm1Dgen
\Kremen2tm1Cni/\Kremen2tm1Cni
either: B6.Cg-Kremen1tm1Dgen Kremen2tm1Cni Dkk1tm1Lmgd or (involves: 129S1/Sv * 129X1/SvJ * CD-1) 		increased bone volume J:137914
polydactyly J:137914
\Kremen1tm1Dgen/\Kremen1tm1Dgen
\Kremen2tm1Cni/\Kremen2tm1Cni
either: B6.Cg-Kremen1tm1Dgen Kremen2tm1Cni or (involves: CD-1) 		abnormal long bone metaphysis morphology J:137914
abnormal osteoblast morphology J:137914
increased bone mineralization J:137914
increased bone ossification J:137914
increased bone volume J:137914
increased osteoblast cell number J:137914
polydactyly J:137914
normal reproductive system phenotype J:137914
\Tg(KRT14-Kremen1)1Smr/0
\Tg(KRT5-rtTA)#Glk/0
\Tg(tetO-Dkk1)1Smr/0
involves: C57BL/6 * FVB/N * SJL 		abnormal hair cycle anagen phase J:204142
abnormal hair growth J:204142
accelerated hair follicle regression J:204142
increased hair follicle apoptosis J:204142
\Tg(tetO-Dkk1)1Smr/0
\Tg(KRT14-Kremen1)1Smr/0
\Tg(KRT14-cre)#Smr/0
involves: C57BL/6J * SJL/J 		abnormal sweat gland morphology J:242196
abnormal tongue morphology J:242196
hypohidrosis J:242196
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory