Kremen1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kremen1
kringle containing transmembrane protein 1
MGI:1933988

15 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Dkk1^tm1Lmgd/Dkk1⁺ Kremen1^tm1Dgen/Kremen1^tm1Dgen Kremen2^tm1Cni/Kremen2^tm1Cni either: B6.Cg-Kremen1^tm1Dgen Kremen2^tm1Cni Dkk1^tm1Lmgd or (involves: 129S1/Sv * 129X1/SvJ * CD-1)	increased bone volume	J:137914
	polydactyly	J:137914
Kremen1^tm1Dgen/Kremen1^tm1Dgen Kremen2^tm1Cni/Kremen2^tm1Cni either: B6.Cg-Kremen1^tm1Dgen Kremen2^tm1Cni or (involves: CD-1)	abnormal long bone metaphysis morphology	J:137914
	abnormal osteoblast morphology	J:137914
	increased bone mineralization	J:137914
	increased bone ossification	J:137914
	increased bone volume	J:137914
	increased osteoblast cell number	J:137914
	polydactyly	J:137914
	normal reproductive system phenotype	J:137914
Tg(KRT14-Kremen1)1Smr/0 Tg(KRT5-rtTA)#Glk/0 Tg(tetO-Dkk1)1Smr/0 involves: C57BL/6 * FVB/N * SJL	abnormal hair cycle anagen phase	J:204142
	abnormal hair growth	J:204142
	accelerated hair follicle regression	J:204142
	increased hair follicle apoptosis	J:204142
Tg(tetO-Dkk1)1Smr/0 Tg(KRT14-Kremen1)1Smr/0 Tg(KRT14-cre)#Smr/0 involves: C57BL/6J * SJL/J	abnormal sweat gland morphology	J:242196
	abnormal tongue morphology	J:242196
	hypohidrosis	J:242196

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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