Krit1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Krit1
KRIT1, ankyrin repeat containing
MGI:1930618

53 phenotypes from 6 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Krit1^{tm1.1(KOMP)Vlcg}/Krit1⁺ C57BL/6N-Krit1^{tm1.1(KOMP)Vlcg}/Ucd	abnormal eye morphology	J:211773
	abnormal heart morphology	J:211773
	absent optic nerve	J:211773
	decreased grip strength	J:211773
	enlarged heart	J:211773
	increased circulating alanine transaminase level	J:211773
Krit1^{tm1.1(KOMP)Vlcg}/Krit1^{tm1.1(KOMP)Vlcg} C57BL/6N-Krit1^{tm1.1(KOMP)Vlcg}/Ucd	abnormal allantois morphology	J:211773
	abnormal blood vessel morphology	J:211773
	abnormal chorioallantoic fusion	J:211773
	abnormal embryo size	J:211773
	abnormal embryo turning	J:211773
	abnormal heart looping	J:211773
	abnormal heart morphology	J:211773
	abnormal left-right axis patterning	J:211773
	abnormal neural tube closure	J:211773
	abnormal neural tube morphology	J:211773
	abnormal optic vesicle formation	J:211773
	abnormal otic vesicle morphology	J:211773
	abnormal pericardium morphology	J:211773
	abnormal pharyngeal arch morphology	J:211773
	abnormal somite shape	J:211773
	embryonic growth retardation	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	pallor	J:211773
	preweaning lethality, complete penetrance	J:211773
Krit1^tm1Arte/Krit1^tm1Arte Tg(Cdh5-cre/ERT2)1Rha/0 involves: C57BL/6	abnormal brain vasculature morphology	J:177584
	abnormal retina vasculature morphology	J:177584
Krit1^tm1Dmar/Krit1^tm1Dmar B6.129-Krit1^tm1Dmar	abnormal artery morphology	J:88138
	abnormal dorsal aorta morphology	J:88138
	abnormal heart development	J:88138
	abnormal intersomitic artery morphology	J:88138
	abnormal visceral yolk sac morphology	J:88138
	dilated aorta	J:88138
	dilated vasculature	J:88138
	embryonic growth arrest	J:88138
	embryonic lethality during organogenesis, complete penetrance	J:88138
	incomplete embryo turning	J:88138
	pharyngeal arch artery stenosis	J:88138
Krit1^tm1Kwhi/Krit1^tm1.1Kwhi Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0 involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCrl * CBA	abnormal blood vessel physiology	J:215458
	abnormal brain vasculature morphology	J:215458
	abnormal retina vasculature morphology	J:215458
	abnormal vascular endothelial cell physiology	J:215458
	eye lesions	J:215458
	increased retina hemangioma incidence	J:215458
	premature death	J:215458
	telangiectasia	J:215458
Krit1^tm1Kwhi/Krit1^tm1.1Kwhi Tg(Tek-cre)1Ywa/0 involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCrl * SJL	abnormal blood circulation	J:215458
	abnormal pharyngeal arch artery morphology	J:215458
	abnormal vascular development	J:215458
	embryonic lethality during organogenesis, complete penetrance	J:215458
Krit1^tm1Kwhi/Krit1^tm1Kwhi Nfatc1^tm1.1(cre)Bz/Nfatc1⁺ involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6NCrl	abnormal heart morphology	J:238897
	abnormal myocardial trabeculae morphology	J:238897
	decreased cardiac jelly amount	J:238897
	dilated heart atrium	J:238897
	dilated heart ventricle	J:238897
	lethality throughout fetal growth and development, complete penetrance	J:238897
	thin myocardium	J:238897
Krit1^tm1Kwhi/Krit1^tm1Kwhi Tg(Cdh5-cre/ERT2)1Rha/0 involves: 129S6/SvEvTac * C57BL/6NCrl	abnormal brain vasculature morphology	J:232707, J:250906
	abnormal venule morphology	J:232707
	premature death	J:232707
Krit1^tm1Sfre/Krit1^tm1Sfre involves: 129P2/OlaHsd * C57BL/6	embryonic lethality during organogenesis, complete penetrance	J:163084

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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