About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Arid1b
AT-rich interaction domain 1B
MGI:1926129
74 phenotypes from 5 alleles in 7 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Arid1bem1(IMPC)Tcp/Arid1b+
C57BL/6NCrl-Arid1bem1(IMPC)Tcp/Tcp 		abnormal freezing behavior J:211773
abnormal spleen morphology J:211773
decreased exploration in new environment J:211773
decreased fasting circulating glucose level J:211773
decreased locomotor activity J:211773
decreased prepulse inhibition J:211773
impaired cued conditioning behavior J:211773
increased circulating creatinine level J:211773
increased freezing behavior J:211773
Arid1bem1(IMPC)Tcp/Arid1bem1(IMPC)Tcp
C57BL/6NCrl-Arid1bem1(IMPC)Tcp/Tcp 		edema J:211773
preweaning lethality, complete penetrance J:211773
Arid1bem1Hzhu/Arid1b+
C57BL/6J-Arid1bem1Hzhu 		abnormal dentate gyrus subgranular zone morphology J:256668
abnormal homeostasis J:256668
abnormal hypothalamus physiology J:256668
abnormal insulin-like growth factor I level J:256668
abnormal response to social novelty J:256668
abnormal vocalization J:256668
normal behavior/neurological phenotype J:256668
decreased body length J:256668
decreased body size J:256668
decreased body weight J:256668
decreased cerebral cortex cell number J:256668
decreased circulating insulin-like growth factor I level J:256668
decreased corpus callosum size J:256668
decreased dentate gyrus size J:256668
decreased grip strength J:256668
decreased heart weight J:256668
decreased kidney weight J:256668
decreased neuron number J:256668
hydrocephaly J:256668
increased anxiety-related response J:256668
increased grooming behavior J:256668
muscle weakness J:256668
postnatal growth retardation J:256668
small heart J:256668
small kidney J:256668
thin cerebral cortex J:256668
Arid1bem1Hzhu/Arid1bem1Hzhu
C57BL/6J-Arid1bem1Hzhu 		decreased birth body size J:256668
perinatal lethality, complete penetrance J:256668
Arid1bem1Iha/Arid1b+
C57BL/6J-Arid1bem1Iha 		abnormal brain vasculature morphology J:271850
abnormal hippocampus pyramidal cell layer J:271850
abnormal long-term spatial reference memory J:271850
abnormal social investigation J:271850
cognitive inflexibility J:271850
decreased body weight J:271850
decreased exploration in new environment J:271850
decreased grip strength J:271850
decreased prepulse inhibition J:271850
decreased startle reflex J:271850
enhanced cued conditioning behavior J:271850
enlarged lateral ventricles J:271850
hydrocephaly J:271850
impaired coordination J:271850
increased anxiety-related response J:271850
increased fear-related response J:271850
increased stereotypic behavior J:271850
increased thermal nociceptive threshold J:271850
slow extinction of fear memory J:271850
Arid1bem1Iha/Arid1bem1Iha
C57BL/6J-Arid1bem1Iha 		lethality, complete penetrance J:271850
Arid1btm1b(EUCOMM)Hmgu/Arid1b+
B6(C)-Arid1btm1b(EUCOMM)Hmgu 		abnormal brain interneuron morphology J:256001
abnormal cerebral cortex morphology J:256001
abnormal inhibitory postsynaptic currents J:256001
abnormal inhibitory synapse morphology J:256001
abnormal lateral ganglionic eminence morphology J:256001
abnormal long-term spatial reference memory J:256001
abnormal medial ganglionic eminence morphology J:256001
abnormal motor learning J:256001
abnormal object recognition memory J:256001
abnormal postsynaptic density morphology J:256001
abnormal symmetric synapse morphology J:256001
abnormal synapse morphology J:256001
decreased coping response J:256001
decreased locomotor activity J:256001
decreased neuronal precursor proliferation J:256001
decreased social investigation J:256001
decreased social novelty preference J:256001
impaired spatial learning J:256001
increased anxiety-related response J:256001
increased grooming behavior J:256001
increased neuron apoptosis J:256001
increased thigmotaxis J:256001
Arid1btm1b(EUCOMM)Hmgu/Arid1btm1b(EUCOMM)Hmgu
C57BL/6N-Arid1btm1b(EUCOMM)Hmgu/Wtsi 		male infertility J:211773
preweaning lethality, incomplete penetrance J:211773
Arid1btm1c(EUCOMM)Hmgu/Arid1b+
Tg(mI56i-cre,-EGFP)1Kc/0
involves: C57BL/6N * FVB/N 		abnormal brain interneuron morphology J:256001
abnormal neurite morphology J:256001
abnormal object recognition memory J:256001
decreased social investigation J:256001
decreased social novelty preference J:256001
increased anxiety-related response J:256001
increased grooming behavior J:256001
Arid1btm1c(EUCOMM)Hmgu/Arid1b+
Tg(Nkx2-1-cre)2Sand/0
involves: C57BL/6 * C57BL/6N 		abnormal brain interneuron morphology J:256001
increased grooming behavior J:256001
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
07/29/2025
MGI 6.24 		The Jackson Laboratory