Tmem138 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tmem138
transmembrane protein 138
MGI:1920232

32 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tmem138^tm1.1Cql/Tmem138^tm1.1Cql involves: C57BL/6 * CBA	abnormal cone electrophysiology	J:369940
	abnormal photoreceptor connecting cilium morphology	J:369940
	abnormal photoreceptor inner segment morphology	J:369940
	abnormal photoreceptor outer segment morphology	J:369940
	abnormal retina cone cell morphology	J:369940
	abnormal retina rod cell outer segment morphology	J:369940
	abnormal rod electrophysiology	J:369940
	absent photoreceptor outer segment	J:369940
	absent sperm flagellum	J:369940
	azoospermia	J:369940
	enhanced autophagy	J:369940
	enlarged brain ventricles	J:369940
	enlarged lateral ventricles	J:369940
	normal growth/size/body region phenotype	J:369940
	hydrocephaly	J:369940
	increased retina apoptosis	J:369940
	photoreceptor outer segment degeneration	J:369940
	retina degeneration	J:369940
	retina gliosis	J:369940
	retina outer nuclear layer degeneration	J:369940
	retina photoreceptor degeneration	J:369940
	retina rod cell degeneration	J:369940
	teratozoospermia	J:369940
	thin retina inner nuclear layer	J:369940
	thin retina outer nuclear layer	J:369940
Tmem138^tm1.1Cql/Tmem138^tm1.2Cql Tg(RHO-cre)1Cya/0 involves: C57BL/6 * CBA	abnormal photoreceptor connecting cilium morphology	J:369940
	abnormal photoreceptor inner segment morphology	J:369940
	abnormal photoreceptor outer segment morphology	J:369940
	abnormal retina rod cell outer segment morphology	J:369940
	disorganized photoreceptor outer segment	J:369940
	photoreceptor outer segment degeneration	J:369940
	retina photoreceptor degeneration	J:369940
Tmem138^{tm1b(EUCOMM)Wtsi}/Tmem138^{tm1b(EUCOMM)Wtsi} C57BL/6N-Tmem138^{tm1b(EUCOMM)Wtsi}/BayMmucd	decreased body length	J:211773
	decreased bone mineral content	J:211773
	decreased grip strength	J:211773
	decreased prepulse inhibition	J:211773
	increased spleen weight	J:211773
	thick ventricular wall	J:211773
Tmem138^tm1Cql/Tmem138^tm1Cql Not Specified	absent sperm flagellum	J:369940
Tmem138^tm1Cql/Tmem138^tm1Cql Not Specified	enlarged lateral ventricles	J:369940

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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