Robo2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Robo2
roundabout guidance receptor 2
MGI:1890110

28 phenotypes from 4 alleles in 12 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Robo2^em1(IMPC)Mbp/Robo2⁺ C57BL/6N-Robo2^em1(IMPC)Mbp/MbpMmucd	abnormal kidney morphology	J:211773
	enlarged kidney	J:211773
Robo2^em1(IMPC)Mbp/Robo2^em1(IMPC)Mbp C57BL/6N-Robo2^em1(IMPC)Mbp/MbpMmucd	abnormal neural tube morphology	J:211773
	edema	J:211773
	hemorrhage	J:211773
	preweaning lethality, complete penetrance	J:211773
Robo2^tm1.1Rilm/Robo2⁺ Tg(Hoxb7-EGFP)33Cos/? involves: 129 * C57BL/6 * CBA * FVB/N	abnormal renal/urinary system morphology	J:125214
	dilated ureter	J:125214
	large ureter	J:125214
Robo2^tm1.1Rilm/Robo2^tm1.1Rilm involves: 129	abnormal brain interneuron morphology	J:130430
	abnormal neurite morphology	J:130430
	perinatal lethality, complete penetrance	J:130430
Robo2^tm1.1Rilm/Robo2^tm1.1Rilm involves: 129 * C57BL/6 * FVB/N	abnormal kidney morphology	J:125214
	kidney cyst	J:125214
	postnatal lethality, complete penetrance	J:125214
	short ureter	J:125214
Robo2^tm1Mrt/Robo2^tm1Mrt involves: 129P2/OlaHsd	abnormal olfactory tract morphology	J:119469
Robo2^tm1Mrt/Robo2^tm1Mrt involves: 129P2/OlaHsd * 129/Sv * C57BL/6 * CD-1	abnormal ureter morphology	J:90324
	postnatal lethality, complete penetrance	J:90324
Robo2^tm1Mrt/Robo2^tm1Mrt involves: 129P2/OlaHsd * C57BL/6	abnormal cerebellar peduncle morphology	J:120131
Robo2^tm1Mrt/Robo2^tm1Mrt involves: 129P2/OlaHsd * C57BL/6	abnormal innervation	J:120131
Robo2^tm1Mrt/Robo2^tm1Mrt Not Specified	abnormal axon guidance	J:89780
Robo2^tm1Mrt/Robo2^tm1Mrt Not Specified	abnormal spinal cord lateral column morphology	J:89780
Robo2^tm1Rilm/Robo2^tm1.1Rilm Tg(EIIa-cre)C5379Lmgd/? involves: 129 * C57BL/6 * FVB/N	abnormal renal/urinary system morphology	J:125214
	abnormal ureter morphology	J:125214
	abnormal ureterovesical junction morphology	J:125214
	abnormal vas deferens morphology	J:125214
	hydronephrosis	J:125214
	kidney cyst	J:125214
	large ureter	J:125214
	short ureter	J:125214
	ureterovesical junction obstruction	J:125214
Robo2^tm1Rilm/Robo2^tm1Rilm involves: 129 * C57BL/6	no abnormal phenotype detected	J:125214
Robo2^tm1Rilm/Robo2^tm1Rilm involves: C57BL/6 * CD-1	abnormal Purkinje cell dendrite morphology	J:221288
Robo2^tm1Rilm/Robo2^tm1Rilm Omp^tm1(cre)Jae/Omp⁺ involves: 129 * 129S1/Sv	abnormal sensory capabilities/reflexes/nociception	J:173325
Robo2^tm1Rilm/Robo2^tm1Rilm Tg(Pcp2-cre)2Mpin/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1	abnormal Purkinje cell dendrite morphology	J:221288

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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