Hs6st1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hs6st1
heparan sulfate 6-O-sulfotransferase 1
MGI:1354958

18 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hs6st1^{Gt(betageo)1Tprt}/Hs6st1^{Gt(betageo)1Tprt} involves: CBA	abnormal retina ganglion layer morphology	J:110040
Hs6st1^tm1.1Wvc/Hs6st1^tm1.1Wvc involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6J	decreased body weight	J:135241
	decreased survivor rate	J:135241
	overexpanded pulmonary alveolus	J:135241
	postnatal growth retardation	J:135241
	postnatal lethality, incomplete penetrance	J:135241
	prenatal lethality, incomplete penetrance	J:135241
Hs6st1^tm1Kkm/Hs6st1^tm1Kkm involves: 129P2/OlaHsd * BALB/c	lethality throughout fetal growth and development, complete penetrance	J:122656
Hs6st1^tm1Kkm/Hs6st1^tm1Kkm involves: 129P2/OlaHsd * C3H/He	lethality throughout fetal growth and development, incomplete penetrance	J:122656
Hs6st1^tm1Kkm/Hs6st1^tm1Kkm involves: 129P2/OlaHsd * C57BL/6	abnormal eye morphology	J:122656
	abnormal phalanx morphology	J:122656
	abnormal placenta vasculature	J:122656
	abnormal pulmonary alveolus morphology	J:122656
	abnormal skeleton development	J:122656
	abnormal tarsal bone morphology	J:122656
	decreased body size	J:122656
	decreased embryo size	J:122656
	lethality throughout fetal growth and development, incomplete penetrance	J:122656
	postnatal growth retardation	J:122656
Hs6st1^tm1Wvc/Hs6st1^tm1Wvc Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: 129S6/SvEvTac * C57BL/6 * DBA	normal homeostasis/metabolism phenotype	J:158299

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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