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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Grem1
gremlin 1, DAN family BMP antagonist
MGI:1344337
14 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
\Alx4lst/\Alx4+
\Grem1ld/\Grem1+
Not Specified 		normal limbs/digits/tail phenotype J:35172
\Alx4lst/\Alx4+
\Grem1ld-J/\Grem1+
involves: CBA/Ca * NHO 		normal limbs/digits/tail phenotype J:35172
\Bmp4tm3.2Blh/\Bmp4+
\Grem1tm1Azun/\Grem1tm1Azun
\Tg(Hoxb7-EGFP)33Cos/?
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * BALB/cJ * C57BL/6 * CBA 		normal renal/urinary system phenotype J:122530
\Bmp4tm3.2Blh/\Bmp4tm3.2Blh
\Grem1tm1Azun/\Grem1tm1Azun
\Tg(Hoxb7-EGFP)33Cos/?
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * BALB/cJ * C57BL/6 * CBA 		prenatal lethality J:122530
\Fmn1tm2Made/\Fmn1+
\Grem1tm1Azun/\Grem1+
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J 		abnormal limb development J:149484
\Grem1tm1Ecan/\Grem1+
\Nogtm1.1Rmh/\Nogtm1.1Rmh
\Tmem163Tg(ACTB-cre)2Mrt/0
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL 		abnormal neural tube morphology J:169133
decreased somite size J:169133
open neural tube J:169133
\Grem1tm1Ecan/\Grem1tm1Ecan
\Nogtm1.1Rmh/\Nogtm1.1Rmh
\Tmem163Tg(ACTB-cre)2Mrt/0
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL 		abnormal brain development J:169133
abnormal head development J:169133
abnormal somite development J:169133
abnormal tail development J:169133
absent sclerotome J:169133
decreased somite size J:169133
kinked neural tube J:169133
open neural tube J:169133
\Grem1tm1Rmh/\Grem1+
\Rr26tm1Svok/\Rr26+
involves: 129P2/OlaHsd * 129X1/SvJ 		normal skeleton phenotype J:207959
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory