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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Csf2
colony stimulating factor 2 (granulocyte-macrophage)
MGI:1339752
34 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Csf1op/Csf1op
Csf2tm1Ard/Csf2tm1Ard
involves: 129P2/OlaHsd * C57BL/6 		abnormal bone marrow morphology J:19089
abnormal pulmonary alveolus morphology J:19089
absent teeth J:19089
decreased leukocyte cell number J:19089
extramedullary hematopoiesis J:19089
increased hemoglobin content J:19089
increased neutrophil cell number J:19089
interstitial pneumonia J:19089
lung inflammation J:19089
osteopetrosis J:19089
polycythemia J:19089
premature death J:19089
pulmonary alveolar proteinosis J:19089
Csf1tm1.1(CSF1)Flv/Csf1tm1.1(CSF1)Flv
Csf2/Il3tm1.1(CSF2,IL3)Flv/Csf2/Il3tm1.1(CSF2,IL3)Flv
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
Tg(SIRPA)1Flv/0
Thpotm1.1(TPO)Flv/Thpotm1.1(TPO)Flv
involves: 129S4/SvJae * BALB/cAnNTac 		abnormal response to transplant J:207289
Csf1tm1.1(CSF1)Flv/Csf1tm1.1(CSF1)Flv
Csf2/Il3tm1.1(CSF2,IL3)Flv/Csf2/Il3tm1.1(CSF2,IL3)Flv
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
Thpotm1.1(TPO)Flv/Thpotm1.1(TPO)Flv
involves: 129S4/SvJae * BALB/cAnNTac 		abnormal response to transplant J:207289
Csf2/Il3tm1.1(CSF2,IL3)Flv/Csf2/Il3tm1.1(CSF2,IL3)Flv
Il2rgtm1.1Flv/Il2rgtm1.1Flv
Rag2tm1.1Flv/Rag2tm1.1Flv
involves: 129S4/SvJae * BALB/cAnNCr * BALB/cAnNTac 		abnormal response to transplant J:168302
Csf2tm1Dran/Csf2tm1Dran
Ifngtm1Ts/Ifngtm1Ts
Il3tm1Glli/Il3tm1Glli
involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6 		increased B cell derived lymphoma incidence J:83086
increased carcinoma incidence J:83086
increased eosinophil cell number J:83086
increased IgE level J:83086
increased IgG1 level J:83086
increased immunoglobulin level J:83086
increased inflammatory response J:83086
increased ovarian carcinoma incidence J:83086
postnatal lethality, incomplete penetrance J:83086
premature death J:83086
Csf2tm1Dran/Csf2tm1Dran
Il3tm1Glli/Il3tm1Glli
B6.129S2-Csf2tm1Dran Il3tm1Glli 		abnormal leukocyte physiology J:83086
abnormal surfactant secretion J:83086
decreased susceptibility to type IV hypersensitivity reaction J:67404
glomerulonephritis J:83086
increased anti-double stranded DNA antibody level J:83086
increased eosinophil cell number J:67404
lung inflammation J:67404
Csf2tm1Dran/Csf2tm1Dran
Il3tm1Glli/Il3tm1Glli
C.129S2-Csf2tm1Dran Il3tm1Glli 		abnormal surfactant secretion J:67404
decreased susceptibility to type IV hypersensitivity reaction J:67404
increased eosinophil cell number J:67404
lung inflammation J:67404
Csf2tm1Mlg/Csf2tm1Mlg
Ifngtm1Ts/Ifngtm1Ts
Il3tm1Glli/Il3tm1Glli
B6.129S-Csf2tm1Mlg Il3tm1Glli Ifngtm1TsIfngtm1Ts 		normal homeostasis/metabolism phenotype J:145518
increased pituitary adenoma incidence J:145518
Csf2tm1Mlg/Csf2tm1Mlg
Il3tm1Glli/Il3tm1Glli
B6.129S2-Csf2tm1Mlg Il3tm1Glli 		abnormal pancreatic islet morphology J:145518
decreased pancreatic beta cell number J:145518
hyperglycemia J:145518
impaired glucose tolerance J:145518
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory