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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Rev3l
REV3 like, DNA directed polymerase zeta catalytic subunit
MGI:1337131
11 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
\Gt(ROSA)26Sortm1(EYFP)Cos/\Gt(ROSA)26Sor+
\Cd19tm1(cre)Cgn/\Cd19+
\Rev3ltm1.1Diaz/\Rev3ltm1.1Diaz
involves: 129P2/OlaHsd * 129X1/SvJ * BALB/c * C57BL/6 * C57BL/6NTac 		abnormal class switch recombination J:188723
abnormal somatic hypermutation frequency J:188723
decreased B cell proliferation J:188723
normal immune system phenotype J:188723
\Rev3ltm1Ndew/\Rev3ltm1Ndew
\Trp53tm1Tyj/\Trp53tm1Tyj
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 		abnormal embryonic tissue morphology J:75450
embryonic lethality during organogenesis, complete penetrance J:75450
\Rev3ltm1Rwd/\Rev3ltm2.1Rwd
\Trp53tm1Brd/\Trp53+
\Tg(MMTV-cre)1Mam/0
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * FVB/N 		increased carcinoma incidence J:158922
increased mammary gland tumor incidence J:158922
increased osteosarcoma incidence J:158922
\Rev3ltm1Rwd/\Rev3ltm2.1Rwd
\Trp53tm1Brd/\Trp53tm1Brd
\Tg(MMTV-cre)1Mam/0
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * FVB/N 		increased T cell derived lymphoma incidence J:158922
premature death J:158922
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory