About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Trp63
transformation related protein 63
MGI:1330810
26 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
\Dlx5tm1Levi/\Dlx5/Dlx6tm1Levi
\Trp63tm1Aam/\Trp63tm1Aam
involves: 129P2/OlaHsd 		abnormal phalanx morphology J:135784
ectrodactyly J:135784
monodactyly J:135784
syndactyly J:135784
\Kdf1shd/\Kdf1shd
\Trp63tm2Brd/\Trp63+
involves: 129S7/SvEvBrd * C3HeB/FeJ * C57BL/6J 		normal integument phenotype J:203995
normal limbs/digits/tail phenotype J:203995
\Trp53tm1Tyj/\Trp53+
\Trp63tm1Fmc/\Trp63+
involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 		increased chronic myelocytic leukemia incidence J:98958
increased mammary adenocarcinoma incidence J:98958
increased metastatic potential J:98958
increased osteosarcoma incidence J:98958
increased rhabdomyosarcoma incidence J:98958
increased squamous cell carcinoma incidence J:98958
increased T cell derived lymphoma incidence J:98958
increased tumor incidence J:98958
increased urinary bladder transitional cell carcinoma incidence J:98958
intervertebral disk degeneration J:98958
premature aging J:98958
premature death J:98958
\Trp53tm1Tyj/\Trp53tm1Tyj
\Trp63tm1.1Elrf/\Trp63tm1.1Elrf
either: (involves: 129S2/SvPas * C57BL/6 * FVB/N) or (involves: 129S2/SvPas * 129S4/SvJae * 129S6/SvEvTac * C57BL/6) 		abnormal skin physiology J:151638
early cellular replicative senescence J:151638
\Trp63tm1Aam/\Trp63tm1Aam
\Dlx5tm1Levi/\Dlx5/Dlx6tm1Levi
involves: 129P2/OlaHsd 		abnormal phalanx morphology J:135784
ectrodactyly J:135784
monodactyly J:135784
syndactyly J:135784
\Trp63tm1Fmc/\Trp63+
\Trp73tm1Fmc/\Trp73+
involves: 129S4/SvJae * C57BL/6 		increased carcinoma incidence J:98958
increased chronic myelocytic leukemia incidence J:98958
increased hemangiosarcoma incidence J:98958
increased lung adenocarcinoma incidence J:98958
increased lung adenoma incidence J:98958
increased mammary adenocarcinoma incidence J:98958
increased metastatic potential J:98958
increased salivary gland adenoma incidence J:98958
increased squamous cell carcinoma incidence J:98958
increased T cell derived lymphoma incidence J:98958
increased tumor incidence J:98958
intervertebral disk degeneration J:98958
paralysis J:98958
premature aging J:98958
premature death J:98958
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory