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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Trp63
transformation related protein 63
MGI:1330810
26 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Dlx5tm1Levi/Dlx5/Dlx6tm1Levi
Trp63tm1Aam/Trp63tm1Aam
involves: 129P2/OlaHsd 		abnormal phalanx morphology J:135784
ectrodactyly J:135784
monodactyly J:135784
syndactyly J:135784
Kdf1shd/Kdf1shd
Trp63tm2Brd/Trp63+
involves: 129S7/SvEvBrd * C3HeB/FeJ * C57BL/6J 		normal integument phenotype J:203995
normal limbs/digits/tail phenotype J:203995
Trp53tm1Tyj/Trp53+
Trp63tm1Fmc/Trp63+
involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 		increased chronic myelocytic leukemia incidence J:98958
increased mammary adenocarcinoma incidence J:98958
increased metastatic potential J:98958
increased osteosarcoma incidence J:98958
increased rhabdomyosarcoma incidence J:98958
increased squamous cell carcinoma incidence J:98958
increased T cell derived lymphoma incidence J:98958
increased tumor incidence J:98958
increased urinary bladder transitional cell carcinoma incidence J:98958
intervertebral disk degeneration J:98958
premature aging J:98958
premature death J:98958
Trp53tm1Tyj/Trp53tm1Tyj
Trp63tm1.1Elrf/Trp63tm1.1Elrf
either: (involves: 129S2/SvPas * C57BL/6 * FVB/N) or (involves: 129S2/SvPas * 129S4/SvJae * 129S6/SvEvTac * C57BL/6) 		abnormal skin physiology J:151638
early cellular replicative senescence J:151638
Trp63tm1Aam/Trp63tm1Aam
Dlx5tm1Levi/Dlx5/Dlx6tm1Levi
involves: 129P2/OlaHsd 		abnormal phalanx morphology J:135784
ectrodactyly J:135784
monodactyly J:135784
syndactyly J:135784
Trp63tm1Fmc/Trp63+
Trp73tm1Fmc/Trp73+
involves: 129S4/SvJae * C57BL/6 		increased carcinoma incidence J:98958
increased chronic myelocytic leukemia incidence J:98958
increased hemangiosarcoma incidence J:98958
increased lung adenocarcinoma incidence J:98958
increased lung adenoma incidence J:98958
increased mammary adenocarcinoma incidence J:98958
increased metastatic potential J:98958
increased salivary gland adenoma incidence J:98958
increased squamous cell carcinoma incidence J:98958
increased T cell derived lymphoma incidence J:98958
increased tumor incidence J:98958
intervertebral disk degeneration J:98958
paralysis J:98958
premature aging J:98958
premature death J:98958
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory