60 phenotypes from 3 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Trex1em3Gpt/Trex1em3Gpt C57BL/6JGpt-Trex1em3Gpt	decreased body size	J:330879
	decreased body weight	J:330879
	enlarged spleen	J:330879
	increased circulating tumor necrosis factor level	J:330879
	increased spleen weight	J:330879
	increased susceptibility to autoimmune disorder	J:330879
	premature death	J:330879
Trex1tm1.1Fwpe/Trex1+ involves: 129S1/SvImJ * 129S4/SvJae * 129S6/SvEvTac	increased CD4-positive, alpha-beta T cell number	J:220965
Trex1tm1.1Fwpe/Trex1tm1.1Fwpe involves: 129S1/SvImJ * 129S4/SvJae * 129S6/SvEvTac	abnormal atrial thrombosis	J:220965
	abnormal heart morphology	J:220965
	abnormal immune system organ morphology	J:220965
	abnormal kidney morphology	J:220965
	abnormal T cell activation	J:220965
	atelectasis	J:220965
	bronchiolitis	J:220965
	congestive heart failure	J:220965
	decreased litter size	J:220965
	dilated heart atrium	J:220965
	dilated heart ventricle	J:220965
	enlarged heart	J:220965
	enlarged lymph nodes	J:220965
	enlarged spleen	J:220965
	glomerulonephritis	J:220965
	heart inflammation	J:220965
	increased anti-double stranded DNA antibody level	J:220965
	increased B cell number	J:220965
	increased CD4-positive, alpha-beta T cell number	J:220965
	increased IgG level	J:220965
	increased inflammatory response	J:220965
	increased plasma cell number	J:220965
	increased regulatory T cell number	J:220965
	increased spleen weight	J:220965
	increased splenocyte number	J:220965
	increased susceptibility to systemic lupus erythematosus	J:220965
	lacrimal gland inflammation	J:220965
	liver vascular congestion	J:220965
	lymphoid hyperplasia	J:220965
	pancreas inflammation	J:220965
	premature death	J:220965
	renal glomerular immunoglobulin deposits	J:220965
	salivary gland inflammation	J:220965
	tubulointerstitial nephritis	J:220965
	vascular inflammation	J:220965
Trex1tm1Tld/Trex1tm1Tld involves: 129P2/OlaHsd	abnormal atrial thrombosis	J:92264
	abnormal interferon secretion	J:234263
	abnormal myocardial fiber morphology	J:92264
	abnormal spleen marginal zone morphology	J:92264
	cardiomyopathy	J:92264
	enlarged lymph nodes	J:92264
	enlarged spleen	J:92264
	heart inflammation	J:202757
	hepatic necrosis	J:92264
	increased autoantibody level	J:202757
	increased spleen B cell follicle size	J:92264
	myocardial fiber degeneration	J:92264
	myocarditis	J:92264
	premature death	J:92264, J:202757
	renal necrosis	J:92264
	skin inflammation	J:202757
	thymus cortex hypoplasia	J:92264
Trex1tm1Tld/Trex1tm1Tld involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6N	heart inflammation	J:234263
	increased autoantibody level	J:234263
	increased inflammatory response	J:234263
	kidney inflammation	J:234263
	myositis	J:234263
	premature death	J:234263
	stomach inflammation	J:234263
Trex1tm1Tld/Trex1tm1Tld involves: 129P2/OlaHsd * C57BL/6	cardiac fibrosis	J:181257
	dermatitis	J:181257
	folliculitis	J:181257
	glomerulonephritis	J:181257
	normal immune system phenotype	J:181257
	increased anti-nuclear antigen antibody level	J:181257
	increased IgG level	J:181257
	increased inflammatory response	J:181257
	increased susceptibility to systemic lupus erythematosus	J:181257
	kidney inflammation	J:181257
	myocarditis	J:181257
	myositis	J:181257
	premature death	J:181257
	skin inflammation	J:181257
	stomach inflammation	J:181257
Trex1tm1Tld/Trex1tm1Tld involves: 129P2/OlaHsd * C57BL/6J	dermatitis	J:243357
	increased susceptibility to autoimmune disorder	J:243357
	skin lesions	J:243357