Kpna6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kpna6
karyopherin subunit alpha 6
MGI:1100836

32 phenotypes from 4 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kpna6^em1Btlr/Kpna6^em1Btlr C57BL/6J-Kpna6^em1Btlr/Btlr	short femur	J:309727
Kpna6^em1Btlr/Kpna6^em1Btlr C57BL/6J-Kpna6^em1Btlr/Btlr	short tibia	J:309727
Kpna6^{Gt(AJ0609)Wtsi}/Kpna6^{Gt(AJ0609)Wtsi} B6N.129P2-Kpna6^{Gt(AJ0609)Wtsi}	abnormal seminiferous tubule morphology	J:311959
	abnormal Sertoli cell barrier function	J:311959
	abnormal Sertoli cell morphology	J:311959
	abnormal spermatid morphology	J:311959
	abnormal spermatocyte morphology	J:311959
	abnormal spermatogenesis	J:311959
	decreased body weight	J:311959
	decreased Sertoli cell number	J:311959
	ectopic Sertoli cells	J:311959
	oligozoospermia	J:311959
	postnatal growth retardation	J:311959
	prenatal lethality, incomplete penetrance	J:311959
	normal reproductive system phenotype	J:311959
Kpna6^{Gt(AJ0609)Wtsi}/Kpna6^{Gt(AJ0609)Wtsi} involves: 129P2/OlaHsd * C57BL/6	female infertility	J:171441
Kpna6^{Gt(AJ0609)Wtsi}/Kpna6^tm1Bdr B6N.Cg-Kpna6^{Gt(AJ0609)Wtsi} Kpna6^tm1Bdr	oligozoospermia	J:311959
	normal reproductive system phenotype	J:311959
Kpna6^m1Btlr/Kpna6^m1Btlr C57BL/6J-Kpna6^m1Btlr/Btlr	short tibia	J:309727
Kpna6^tm1Bdr/Kpna6^tm1Bdr B6N.Cg-Kpna6^tm1Bdr	abnormal caput epididymis morphology	J:311959
	abnormal cauda epididymis morphology	J:311959
	abnormal epididymis morphology	J:311959
	abnormal seminiferous tubule epithelium morphology	J:311959
	abnormal seminiferous tubule morphology	J:311959
	abnormal Sertoli cell barrier function	J:311959
	abnormal Sertoli cell morphology	J:311959
	abnormal sperm head morphology	J:311959
	abnormal spermatid morphology	J:311959
	abnormal spermatocyte morphology	J:311959
	abnormal spermatogenesis	J:311959
	abnormal spermiation	J:311959
	abnormal spermiogenesis	J:311959
	decreased body weight	J:311959
	decreased male germ cell number	J:311959
	decreased Sertoli cell number	J:311959
	decreased testis weight	J:311959
	ectopic Sertoli cells	J:311959
	increased male germ cell apoptosis	J:311959
	male infertility	J:311959
	multinucleated giant male germ cells	J:311959
	oligozoospermia	J:311959
	postnatal growth retardation	J:311959
	prenatal lethality, incomplete penetrance	J:311959
	small seminiferous tubules	J:311959
	small testis	J:311959
Kpna6^tm1Bdr/Kpna6^tm1Bdr involves: C57BL/6	abnormal pregnancy	J:171441
	female infertility	J:171441
	maternal effect	J:171441

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