126 phenotypes from 10 alleles in 13 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nfkb2Lym1/Nfkb2+ BALB/c-Nfkb2Lym1	abnormal lymph node morphology	J:154812
	abnormal mesenteric lymph node morphology	J:154812
	abnormal spleen white pulp morphology	J:154812
	absent axillary lymph nodes	J:154812
	absent brachial lymph nodes	J:154812
	absent cervical lymph nodes	J:154812
	absent inguinal lymph nodes	J:154812
	absent Peyer's patches	J:154812
	decreased lymph node number	J:154812
	increased lymphocyte cell number	J:154812
	liver inflammation	J:154812
	lung inflammation	J:154812
Nfkb2Lym1/Nfkb2+ involves: BALB/c	abnormal B cell differentiation	J:188560
Nfkb2Lym1/Nfkb2Lym1 involves: BALB/c	abnormal class switch recombination	J:154812
	abnormal lymph node morphology	J:154812
	abnormal osteoclast differentiation	J:154812
	abnormal peripheral lymph node morphology	J:154812
	abnormal plasma cell differentiation	J:154812
	abnormal spleen follicular dendritic cell network	J:154812
	abnormal spleen periarteriolar lymphoid sheath morphology	J:154812
	abnormal spleen primary B follicle morphology	J:154812
	abnormal spleen white pulp morphology	J:154812
	abnormal T cell differentiation	J:154812
	abnormal thymus cell ratio	J:154812
	abnormal thymus physiology	J:154812
	abnormal thymus size	J:154812
	abnormal trabecular bone morphology	J:154812
	absent axillary lymph nodes	J:154812
	absent brachial lymph nodes	J:154812
	absent cervical lymph nodes	J:154812
	absent inguinal lymph nodes	J:154812
	absent mesenteric lymph nodes	J:154812
	absent Peyer's patches	J:154812
	autoimmune response	J:154812
	decreased B cell proliferation	J:154812
	decreased follicular B cell number	J:154812
	decreased IgA level	J:154812
	decreased IgG1 level	J:154812
	decreased IgG2b level	J:154812
	decreased IgM level	J:154812
	decreased immunoglobulin level	J:154812
	decreased litter size	J:154812
	decreased lymph node number	J:154812
	decreased marginal zone B cell number	J:154812
	decreased mature B cell number	J:154812
	decreased transitional stage B cell number	J:154812
	enlarged spleen	J:154812
	extramedullary hematopoiesis	J:154812
	normal hematopoietic system phenotype	J:154812
	increased CD4-positive, alpha-beta T cell number	J:154812
	increased CD8-positive, alpha-beta T cell number	J:154812
	increased double-negative T cell number	J:154812
	increased double-positive T cell number	J:154812
	increased spleen red pulp amount	J:154812
	increased spleen weight	J:154812
	increased transitional stage B cell number	J:154812
	liver inflammation	J:154812
	lung inflammation	J:154812
	osteopetrosis	J:154812
	premature death	J:154812
	reduced fertility	J:154812
Nfkb2m2Btlr/Nfkb2m2Btlr C57BL/6J-Nfkb2m2Btlr	increased B-1a cell number	J:221493
Nfkb2m3Btlr/Nfkb2m3Btlr C57BL/6J-Nfkb2m3Btlr	abnormal B cell differentiation	J:274960
	abnormal CD4-positive T cell differentiation	J:274960
	abnormal CD8-positive, alpha-beta T cell differentiation	J:274960
	abnormal T cell differentiation	J:274960
	decreased B cell number	J:274960
	decreased CD4-positive, alpha-beta T cell number	J:274960
	decreased effector memory CD8-positive, alpha-beta T cell number	J:274960
	decreased NK cell number	J:274960
	increased B-1 B cell number	J:274960
	increased CD4-positive, alpha-beta T cell number	J:274960
	increased CD8-positive, alpha-beta T cell number	J:274960
	increased CD8-positive, naive alpha-beta T cell number	J:274960
	increased T cell number	J:274960
Nfkb2M4Btlr/Nfkb2M4Btlr C57BL/6J-Nfkb2M4Btlr	increased CD4-positive, alpha-beta T cell number	J:274961
	increased CD8-positive, alpha-beta T cell number	J:274961
	increased T cell number	J:274961
Nfkb2m5Btlr/Nfkb2m5Btlr C57BL/6J-Nfkb2m5Btlr	increased B-1 B cell number	J:274962
Nfkb2tm1Brv/Nfkb2+ involves: 129S1/Sv * C57BL/6	stomach epithelial hyperplasia	J:43469
Nfkb2tm1Brv/Nfkb2tm1Brv involves: 129S1/Sv * C57BL/6	abnormal bone marrow morphology	J:43469
	abnormal cytokine secretion	J:43469
	abnormal definitive hematopoiesis	J:43469
	abnormal food intake	J:43469
	abnormal lymph node B cell domain morphology	J:43469
	abnormal lymph node cortex morphology	J:43469
	abnormal lymphocyte cell number	J:43469
	abnormal stomach cardiac region morphology	J:43469
	abnormal T cell number	J:43469
	abnormal T cell subpopulation ratio	J:43469
	abnormal thymus corticomedullary boundary morphology	J:43469
	anemia	J:43469
	decreased body size	J:43469
	decreased body weight	J:43469
	decreased double-positive T cell number	J:43469
	decreased spleen weight	J:43469
	disheveled coat	J:43469
	enlarged lymph nodes	J:43469
	hunched posture	J:43469
	increased B cell proliferation	J:43469
	increased granulocyte number	J:43469
	increased interleukin-2 secretion	J:43469
	increased interleukin-4 secretion	J:43469
	increased interleukin-10 secretion	J:43469
	increased T cell proliferation	J:43469
	increased tumor necrosis factor secretion	J:43469
	intermingled spleen red and white pulp	J:43469
	premature death	J:43469
	small stomach	J:43469
	spleen atrophy	J:43469
	spleen hypoplasia	J:43469
	stomach epithelial hyperplasia	J:43469
	thymus atrophy	J:43469
	weight loss	J:43469
Nfkb2tm1Rsch/Nfkb2tm1Rsch involves: 129P2/OlaHsd	abnormal myeloid dendritic cell morphology	J:77049
	abnormal Peyer's patch follicle morphology	J:77049
	abnormal Peyer's patch germinal center morphology	J:77049
	abnormal Peyer's patch morphology	J:77049
	abnormal Peyer's patch T cell area morphology	J:77049
	decreased B cell number	J:77049
	decreased dendritic cell number	J:77049
	decreased myeloid dendritic cell number	J:77049
	increased plasmacytoid dendritic cell number	J:77049
	small Peyer's patches	J:77049
Nfkb2tm1Sbn/Nfkb2tm1Sbn involves: 129S4/SvJae	decreased fibroblast cell migration	J:159873
	decreased fibroblast chemotaxis	J:159873
Nfkb2tm1Sbn/Nfkb2tm1Sbn involves: 129S4/SvJae * C57BL/6	abnormal class switch recombination	J:45437
	abnormal immunoglobulin level	J:45437
	abnormal lymphocyte cell number	J:45437
	abnormal metallophilic macrophage morphology	J:45437
	abnormal spleen B cell follicle morphology	J:45437
	abnormal spleen marginal zone macrophage morphology	J:45437
	abnormal spleen marginal zone morphology	J:45437
	abnormal spleen white pulp morphology	J:45437
	absent spleen germinal center	J:45437
	decreased B cell number	J:45437
	decreased IgA level	J:45437
	decreased IgG1 level	J:45437
	decreased IgG2a level	J:45437
	decreased IgG2b level	J:45437
	increased IgM level	J:45437
	increased susceptibility to induced morbidity/mortality	J:45437
	increased susceptibility to parasitic infection	J:45437
	increased T cell number	J:45437
Nfkb2tm2Brv/Nfkb2tm2Brv involves: 129S1/Sv	abnormal gamma-delta T cell morphology	J:169863
	decreased gamma-delta T cell number	J:169863
Nfkb2tm2Brv/Nfkb2tm2Brv involves: 129S1/Sv * C57BL/6	abnormal lymph node morphology	J:76380
	abnormal metallophilic macrophage morphology	J:76380
	abnormal spleen morphology	J:76380
	absent lymph node germinal center	J:76380
	absent spleen germinal center	J:76380
	absent spleen marginal zone	J:76380
	decreased B cell number	J:76380
	decreased B cell proliferation	J:76380
	decreased IgA level	J:76380
	decreased IgG1 level	J:76380
	decreased IgG3 level	J:76380
	increased CD4-positive, alpha-beta T cell number	J:76380
	increased CD8-positive, alpha-beta T cell number	J:76380
	increased IgG2a level	J:76380
	increased IgM level	J:76380
	increased splenocyte apoptosis	J:76380
Nfkb2xdr/Nfkb2xdr C57BL/6JSfdAnu-Nfkb2xdr/Anu	abnormal metallophilic macrophage morphology	J:79725
	abnormal peripheral lymph node morphology	J:79725
	abnormal spleen follicular dendritic cell network	J:79725
	abnormal spleen morphology	J:79725
	abnormal spleen secondary B follicle morphology	J:79725
	decreased B-2 B cell number	J:79725
	decreased follicular B cell number	J:79725
	decreased marginal zone B cell number	J:79725
	decreased mature B cell number	J:79725
	decreased transitional stage T2 B cell number	J:79725
	normal hematopoietic system phenotype	J:79725
	increased B-1 B cell number	J:79725
Nfkb2xdr/Nfkb2xdr involves: C57BL/6JSfdAnu * C57BL/10Sg * C57BR/cd * NOD	decreased B cell number	J:79725