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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Nrxn1
neurexin I
MGI:1096391
27 phenotypes from 5 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Nrxn1tm1b(KOMP)Wtsi/Nrxn1+
C57BL/6N-Nrxn1tm1b(KOMP)Wtsi/H
enlarged stomach J:211773
increased circulating amylase level J:211773
increased lean body mass J:211773
small thymus J:211773
tremors J:211773
Nrxn1tm1b(KOMP)Wtsi/Nrxn1tm1b(KOMP)Wtsi
C57BL/6N-Nrxn1tm1b(KOMP)Wtsi/H
abnormal bone structure J:211773
decreased circulating alkaline phosphatase level J:211773
decreased circulating cholesterol level J:211773
decreased circulating HDL cholesterol level J:211773
decreased circulating serum albumin level J:211773
decreased circulating total protein level J:211773
decreased fasting circulating glucose level J:211773
decreased grip strength J:211773
decreased pulmonary respiratory rate J:211773
decreased total body fat amount J:211773
impaired glucose tolerance J:211773
increased circulating aspartate transaminase level J:211773
tremors J:211773
Nrxn1tm1Sud/Nrxn1tm1Sud
involves: 129
abnormal nervous system physiology J:115214
decreased synaptic glutamate release J:115214
Nrxn1tm1Sud/Nrxn1tm1Sud
involves: 129 * C57BL/6
abnormal excitatory postsynaptic currents J:153748
abnormal miniature excitatory postsynaptic currents J:153748
abnormal motor learning J:153748
abnormal nest building behavior J:153748
normal behavior/neurological phenotype J:153748
decreased prepulse inhibition J:153748
increased grooming behavior J:153748
Nrxn1tm2Sud/Nrxn1tm2Sud
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
no abnormal phenotype detected J:101977
Nrxn1tm3Sud/Nrxn1tm3Sud
B6.129-Nrxn1tm3Sud
no abnormal phenotype detected J:101977
Nrxn1tm5Sud/Nrxn1tm5Sud
involves: C57BL/6
no abnormal phenotype detected J:101977

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory