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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ltbr
lymphotoxin B receptor
MGI:104875
44 phenotypes from 8 alleles in 11 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cd19tm1(cre)Cgn/Cd19+
Ltbrtm1Avt/Ltbrtm1Avt
involves: 129P2/OlaHsd 		normal immune system phenotype J:158663
Cd19tm1(cre)Cgn/Cd19+
Ltbrtm1Avt/Ltbrtm1Avt
Tg(Lck-cre)I57Jxm/0
involves: 129P2/OlaHsd 		normal immune system phenotype J:158663
Ltbrm1Btlr/Ltbrm1Btlr
C57BL/6J-Ltbrm1Btlr 		abnormal B cell physiology J:212068
abnormal humoral immune response J:212068
Ltbrm2Btlr/Ltbrm2Btlr
C57BL/6J-Ltbrm2Btlr 		abnormal humoral immune response J:254823
abnormal IgG level J:254823
Ltbrm3Btlr/Ltbrm3Btlr
C57BL/6J-Ltbrm3Btlr 		impaired natural killer cell mediated cytotoxicity J:264642
increased NK T cell number J:264642
Ltbrm4Btlr/Ltbrm4Btlr
C57BL/6J-Ltbrm4Btlr 		decreased alpha-beta T cell number J:264820
decreased CD4-positive, alpha-beta T cell number J:264820
decreased CD8-positive, alpha-beta T cell number J:264820
decreased NK cell number J:264820
decreased single-positive T cell number J:264820
increased B cell number J:264820
increased B-1 B cell number J:264820
Ltbrtm1.1Thhe/Ltbrtm1.1Thhe
involves: 129P2/OlaHsd * C57BL/6 * SJL 		no abnormal phenotype detected J:183109
Ltbrtm1.1Thhe/Ltbrtm1.1Thhe
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * C57BL/6 * SJL 		abnormal macrophage physiology J:183109
Ltbrtm1Avt/Ltbrtm1Avt
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd 		increased susceptibility to bacterial infection J:158663
Ltbrtm1Avt/Ltbrtm1Avt
Tg(Lck-cre)I57Jxm/0
Not Specified 		normal immune system phenotype J:158663
Ltbrtm1Avt/Ltbrtm1Avt
Tg(Rorc-cre)1Litt/0
Not Specified 		abnormal chemokine level J:158663
abnormal colon morphology J:158663
decreased neutrophil cell number J:158663
increased susceptibility to bacterial infection J:158663
increased susceptibility to bacterial infection induced morbidity/mortality J:158663
weight loss J:158663
Ltbrtm1Avt/Ltbrtm1Avt
Tg(Vil1-cre)997Gum/0
involves: C57BL/6J * SJL 		decreased neutrophil cell number J:158663
increased susceptibility to bacterial infection J:158663
Ltbrtm1Kpf/Ltbrtm1Kpf
B6.129P2-Ltbrtm1Kpf 		decreased neutrophil cell number J:158663
Ltbrtm1Kpf/Ltbrtm1Kpf
involves: 129P2/OlaHsd 		abnormal gamma-delta T cell morphology J:169863
abnormal immune system morphology J:48837
abnormal immune system organ morphology J:48837
abnormal immune system physiology J:48837
abnormal spleen B cell follicle morphology J:48837
abnormal spleen morphology J:48837
abnormal spleen periarteriolar lymphoid sheath morphology J:48837
absent marginal zone B cells J:48837
absent peripheral lymph nodes J:48837
absent Peyer's patches J:48837
decreased IgE level J:86810
decreased interleukin-17 secretion J:169863
enlarged spleen J:48837
normal immune system phenotype J:169863
increased B cell number J:48837
increased lymphocyte cell number J:48837
increased T cell number J:48837
Ltbrtm1Kpf/Ltbrtm1Kpf
involves: 129P2/OlaHsd * C57BL/6 		decreased spleen white pulp amount J:109621
Ltbrtm1Mmat/Ltbrtm1Mmat
involves: C57BL/6 * CBA 		abnormal lymphocyte morphology J:173115
abnormal spleen morphology J:173115
abnormal thymus epithelium morphology J:173115
abnormal thymus medulla morphology J:173115
absent follicular dendritic cells J:173115
absent mesenteric lymph nodes J:173115
absent spleen germinal center J:173115
small thymus medulla J:173115
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory