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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Procr
protein C receptor, endothelial
MGI:104596
32 phenotypes from 7 alleles in 11 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Meox2tm1(cre)Sor/Meox2+
Procrtm1Cte/Procrtm2Cte
involves: 129S4/SvJaeSor * 129S7/SvEvBrd * Black Swiss * C57BL/6 		prenatal lethality, complete penetrance J:119529
Meox2tm1(cre)Sor/Meox2+
Procrtm2Cte/Procrtm2Cte
involves: 129S4/SvJaeSor * 129S7/SvEvBrd * Black Swiss * C57BL/6 		abnormal hematopoietic system morphology/development J:119529
decreased circulating fibrinogen level J:119529
increased circulating C-reactive protein level J:119529
thrombocytopenia J:119529
Procrtm1.1(cre/ERT2)Yaz/Procrtm1.1(cre/ERT2)Yaz
involves: 129P2/OlaHsd * C57BL/6 		embryonic lethality during organogenesis, complete penetrance J:217483
Procrtm1.1Pcl/Procr+
involves: 129S2/SvPas * C57BL/6 		abnormal circulating protein level J:225914
Procrtm1.1Pcl/Procrtm1.1Pcl
involves: 129S2/SvPas * C57BL/6 		abnormal circulating protein level J:225914
bone marrow failure J:225914
decreased bone marrow cell number J:225914
enlarged spleen J:225914
extramedullary hematopoiesis J:225914
normal hematopoietic system phenotype J:225914
increased circulating interleukin-6 level J:225914
increased spleen red pulp amount J:225914
increased spleen weight J:225914
increased splenocyte number J:225914
increased susceptibility to endotoxin shock J:225914
increased susceptibility to induced thrombosis J:225914
normal mortality/aging J:225914
thrombocytopenia J:225914
Procrtm1Cte/Procr+
B6.129S7-Procrtm1Cte 		abnormal blood coagulation J:144388
thrombocytopenia J:144388
Procrtm1Cte/Procrtm1Cte
either: 129S/SvEv-Procrtm1Cte or (involves: 129S7/SvEvBrd * Black Swiss) 		abnormal blood coagulation J:80043
abnormal extraembryonic tissue morphology J:80043
abnormal placental thrombosis J:80043
decreased embryo size J:80043
embryonic growth retardation J:80043
embryonic lethality during organogenesis, complete penetrance J:80043
incomplete embryo turning J:80043
Procrtm1Cte/Procrtm1Cte
involves: 129S7/SvEvBrd 		prenatal lethality, incomplete penetrance J:119529
Procrtm1Cte/Procrtm1Cte
Tg(Tek-Procr)1Cte/0
involves: 129S7/SvEvBrd * C57BL/6 * FVB/N 		embryonic lethality during organogenesis, complete penetrance J:119529
Procrtm1Fjc/Procrtm1Fjc
involves: 129X1/SvJ 		no abnormal phenotype detected J:80955
Procrtm2Cte/Procrtm3Cte
Meox2tm1(cre)Sor/Meox2+
involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6 		normal mortality/aging J:144388
Procrtm3Cte/Procrtm3Cte
involves: 129S7/SvEvBrd * C57BL/6 		prenatal lethality, complete penetrance J:144388
Tg(Tek-Procr)1Cte/0
B6.FVB-Tg(Tek-Procr)1Cte 		abnormal acute phase protein level J:119637
abnormal blood coagulation J:119637
abnormal enzyme/coenzyme level J:119637
abnormal immune system physiology J:119637
abnormal inflammatory response J:119637
abnormal platelet physiology J:119637
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory