Apobec1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Apobec1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
MGI:103298

18 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apobec1^tm1Chan/Apobec1^tm1Chan Apoe^tm1Unc/Apoe^tm1Unc involves: 129P2/OlaHsd * 129S4/SvJae	abnormal circulating cholesterol level	J:48202
	decreased circulating cholesterol level	J:48202
	increased circulating cholesterol level	J:48202
	increased circulating triglyceride level	J:48202
Apobec1^tm1Chan/Apobec1^tm1Chan Ldlr^tm1Her/Ldlr^tm1Her involves: 129S4/SvJae * 129S7/SvEvBrd	abnormal circulating cholesterol level	J:48202
	decreased circulating triglyceride level	J:48202
	increased circulating cholesterol level	J:48202
	increased circulating triglyceride level	J:48202
Apobec1^tm1Chan/Apobec1^tm1Chan Tg(CETP)5203Tall/0 involves: 129S4/SvJae * C57BL/6J * CBA/J	abnormal circulating cholesterol level	J:48202
	decreased circulating HDL cholesterol level	J:48202
	decreased circulating triglyceride level	J:48202
	increased circulating cholesterol level	J:48202
	increased circulating triglyceride level	J:48202
Apobec1^tm1Ddsn/Apobec1^tm1Ddsn Fgg^tm1Fjc/Fgg^tm1Fjc Ldlr^tm1Her/Ldlr^tm1Her B6.129-Fgg^tm1Fjc Apobec1^tm1Ddsn Ldlr^tm1Her	abnormal blood coagulation	J:132734
	atherosclerotic lesions	J:132734
	increased circulating LDL cholesterol level	J:132734
	postnatal lethality, incomplete penetrance	J:135942
Apobec1^tm1Ddsn/Apobec1^tm1Ddsn Ldlr^tm1Her/Ldlr^tm1Her B6.129-Apobec1^tm1Ddsn Ldlr^tm1Her	abnormal blood coagulation	J:132734
	atherosclerotic lesions	J:132734
	decreased partial thromboplastin time	J:132734
	decreased prothrombin time	J:132734
	increased circulating antithrombin level	J:132734
	increased circulating LDL cholesterol level	J:132734
	increased circulating prothrombin level	J:132734
Apobec1^tm1Ddsn/Apobec1^tm1Ddsn Ldlr^tm1Her/Ldlr^tm1Her involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6	atherosclerotic lesions	J:49125
	increased circulating cholesterol level	J:49125
	increased circulating LDL cholesterol level	J:49125
	increased circulating triglyceride level	J:49125
Apobec1^tm1Ishi/Apobec1^tm1Ishi Apoe^tm1Unc/Apoe^tm1Unc involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6	decreased cholesterol level	J:41982
	increased circulating triglyceride level	J:41982
Apobec1^tm1Rub/Apobec1^tm1Rub Apoe^{tm1(APOE2)Mae}/Apoe^{tm1(APOE2)Mae} involves: 129P2/OlaHsd * C57BL/6	decreased circulating cholesterol level	J:79196
	decreased circulating LDL cholesterol level	J:79196
	increased circulating HDL cholesterol level	J:79196
	increased circulating triglyceride level	J:79196
	increased circulating VLDL triglyceride level	J:79196

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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