Stk11 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Stk11
serine/threonine kinase 11
MGI:1341870

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0030275	LRR domain binding	IPI	J:155212
Molecular Function	GO:0000287	magnesium ion binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0002039	p53 binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:217430
Molecular Function	GO:0005515	protein binding	IPI	J:277854
Molecular Function	GO:0005515	protein binding	IPI	J:219393
Molecular Function	GO:0005515	protein binding	IPI	J:162066
Molecular Function	GO:0030295	protein kinase activator activity	IDA	J:162066
Molecular Function	GO:0030295	protein kinase activator activity	ISO	J:164563
Molecular Function	GO:0030295	protein kinase activator activity	IMP	J:104202
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IMP	J:104202
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ISO	J:155856
Molecular Function	GO:0004674	protein serine/threonine kinase activity	ISO	J:164563
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IDA	J:175108
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IDA	J:162066
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IBA	J:265628
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IDA	J:56632
Cellular Component	GO:0005737	cytoplasm	IDA	J:155212
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:206380
Cellular Component	GO:0005737	cytoplasm	ISO	J:73065
Cellular Component	GO:0005737	cytoplasm	IDA	J:158624
Cellular Component	GO:0005737	cytoplasm	ISO	J:73065
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:175116
Cellular Component	GO:0140535	intracellular protein-containing complex	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:175116
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:56632
Cellular Component	GO:0005634	nucleus	IDA	J:162066
Cellular Component	GO:0005634	nucleus	IDA	J:175116
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:175207
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:175108
Cellular Component	GO:0005634	nucleus	IDA	J:155212
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:1902554	serine/threonine protein kinase complex	ISO	J:164563
Cellular Component	GO:0030018	Z disc	ISO	J:155856
Biological Process	GO:0032147	activation of protein kinase activity	ISO	J:164563
Biological Process	GO:0032147	activation of protein kinase activity	ISO	J:73065
Biological Process	GO:0032147	activation of protein kinase activity	ISO	J:73065
Biological Process	GO:0043276	anoikis	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0006914	autophagy	IEA	J:60000
Biological Process	GO:0007409	axonogenesis	ISO	J:155856
Biological Process	GO:0007409	axonogenesis	IMP	J:162066
Biological Process	GO:0007409	axonogenesis	IGI	J:168108
Biological Process	GO:0007409	axonogenesis	IGI	J:168108
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0071493	cellular response to UV-B	ISO	J:164563
Biological Process	GO:0071493	cellular response to UV-B	IDA	J:217430
Biological Process	GO:0097484	dendrite extension	IMP	J:206380
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	IMP	J:217430
Biological Process	GO:0006974	DNA damage response	IBA	J:265628
Biological Process	GO:0060767	epithelial cell proliferation involved in prostate gland development	IMP	J:133330
Biological Process	GO:0060767	epithelial cell proliferation involved in prostate gland development	IMP	J:133330
Biological Process	GO:0030010	establishment of cell polarity	ISO	J:164563
Biological Process	GO:0030010	establishment of cell polarity	IMP	J:215076
Biological Process	GO:0030010	establishment of cell polarity	IMP	J:162066
Biological Process	GO:0030010	establishment of cell polarity	ISO	J:155856
Biological Process	GO:0030010	establishment of cell polarity	IBA	J:265628
Biological Process	GO:0070314	G1 to G0 transition	ISO	J:164563
Biological Process	GO:0042593	glucose homeostasis	IMP	J:104202
Biological Process	GO:0051645	Golgi localization	IMP	J:206380
Biological Process	GO:0051645	Golgi localization	IMP	J:168108
Biological Process	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	ISO	J:164563
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	ISS	J:263479
Biological Process	GO:0030308	negative regulation of cell growth	IDA	J:175116
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:217430
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0120163	negative regulation of cold-induced thermogenesis	IMP	J:241164
Biological Process	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	IMP	J:133330
Biological Process	GO:1904262	negative regulation of TORC1 signaling	ISO	J:164563
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0010508	positive regulation of autophagy	ISO	J:164563
Biological Process	GO:0050772	positive regulation of axonogenesis	IGI	J:168108
Biological Process	GO:0045722	positive regulation of gluconeogenesis	ISO	J:155856
Biological Process	GO:1900182	positive regulation of protein localization to nucleus	IMP	J:215277
Biological Process	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	ISO	J:164563
Biological Process	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	IMP	J:134476
Biological Process	GO:1901610	positive regulation of vesicle transport along microtubule	IMP	J:215076
Biological Process	GO:1901610	positive regulation of vesicle transport along microtubule	ISO	J:155856
Biological Process	GO:1901610	positive regulation of vesicle transport along microtubule	ISO	J:164563
Biological Process	GO:1901610	positive regulation of vesicle transport along microtubule	IBA	J:265628
Biological Process	GO:0045059	positive thymic T cell selection	IMP	J:172064
Biological Process	GO:0045059	positive thymic T cell selection	IMP	J:172064
Biological Process	GO:0046777	protein autophosphorylation	IDA	J:175108
Biological Process	GO:0046777	protein autophosphorylation	ISO	J:164563
Biological Process	GO:0006470	protein dephosphorylation	ISO	J:164563
Biological Process	GO:0006470	protein dephosphorylation	ISS	J:263479
Biological Process	GO:0034504	protein localization to nucleus	IMP	J:215277
Biological Process	GO:0034504	protein localization to nucleus	IMP	J:215277
Biological Process	GO:0006468	protein phosphorylation	IDA	J:217430
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IBA	J:265628
Biological Process	GO:0006468	protein phosphorylation	IMP	J:215277
Biological Process	GO:0001558	regulation of cell growth	IDA	J:175108
Biological Process	GO:0048814	regulation of dendrite morphogenesis	IMP	J:206380
Biological Process	GO:0051896	regulation of protein kinase B signaling	IMP	J:133330
Biological Process	GO:0030111	regulation of Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0030111	regulation of Wnt signaling pathway	IMP	J:133330
Biological Process	GO:0010212	response to ionizing radiation	IDA	J:175207
Biological Process	GO:0033993	response to lipid	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IBA	J:265628
Biological Process	GO:0007286	spermatid development	IMP	J:143943
Biological Process	GO:0007283	spermatogenesis	IEA	J:60000
Biological Process	GO:0050852	T cell receptor signaling pathway	IMP	J:172064
Biological Process	GO:0050852	T cell receptor signaling pathway	IGI	J:172064
Biological Process	GO:0001894	tissue homeostasis	IMP	J:133330
Biological Process	GO:0001894	tissue homeostasis	IMP	J:133330
Biological Process	GO:0001894	tissue homeostasis	IMP	J:133330
Biological Process	GO:0001894	tissue homeostasis	IMP	J:133330
Biological Process	GO:0001944	vasculature development	IMP	J:70892

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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