GO Annotations Graph

• Symbol: Rorc
• Name: RAR-related orphan receptor gamma
• ID: MGI:104856

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:199687
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:205648
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:131020
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0098531	ligand-activated transcription factor activity	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004879	nuclear receptor activity	IBA	J:265628
Molecular Function	GO:0008142	oxysterol binding	ISO	J:164563
Molecular Function	GO:0008142	oxysterol binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:274080
Molecular Function	GO:0005515	protein binding	IPI	J:213087
Molecular Function	GO:0005515	protein binding	IPI	J:224726
Molecular Function	GO:0005515	protein binding	IPI	J:176230
Molecular Function	GO:0005515	protein binding	IPI	J:136164
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	IEA	J:72247
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0001223	transcription coactivator binding	IPI	J:116733
Molecular Function	GO:0001223	transcription coactivator binding	IPI	J:122764
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:190936
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-8949303
Cellular Component	GO:0005634	nucleus	IDA	J:136164
Cellular Component	GO:0005634	nucleus	IDA	J:199687
Cellular Component	GO:0005634	nucleus	IDA	J:213087
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0060612	adipose tissue development	IMP	J:205648
Biological Process	GO:0046632	alpha-beta T cell differentiation	IMP	J:91566
Biological Process	GO:0046632	alpha-beta T cell differentiation	IMP	J:91566
Biological Process	GO:0030154	cell differentiation	IMP	J:87395
Biological Process	GO:0036315	cellular response to sterol	ISO	J:164563
Biological Process	GO:0032922	circadian regulation of gene expression	IMP	J:199687
Biological Process	GO:0032922	circadian regulation of gene expression	IMP	J:213087
Biological Process	GO:0048535	lymph node development	IMP	J:87395
Biological Process	GO:0048537	mucosa-associated lymphoid tissue development	IMP	J:91566
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0070244	negative regulation of thymocyte apoptotic process	IMP	J:116733
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0048541	Peyer's patch development	IMP	J:87395
Biological Process	GO:0042753	positive regulation of circadian rhythm	IDA	J:199687
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:213898
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:213087
Biological Process	GO:0006468	protein phosphorylation	IMP	J:93872
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0045598	regulation of fat cell differentiation	IMP	J:205648
Biological Process	GO:0045586	regulation of gamma-delta T cell differentiation	IDA	J:174553
Biological Process	GO:0010906	regulation of glucose metabolic process	IMP	J:205671
Biological Process	GO:0019218	regulation of steroid metabolic process	IMP	J:207076
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:131020
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0048511	rhythmic process	IEA	J:60000
Biological Process	GO:0033077	T cell differentiation in thymus	IMP	J:91566
Biological Process	GO:0072539	T-helper 17 cell differentiation	IMP	J:115922
Biological Process	GO:0072539	T-helper 17 cell differentiation	IMP	J:131020
Biological Process	GO:0072539	T-helper 17 cell differentiation	IMP	J:159461
Biological Process	GO:0072539	T-helper 17 cell differentiation	IDA	J:141227
Biological Process	GO:0042093	T-helper cell differentiation	IMP	J:87395
Biological Process	GO:0006805	xenobiotic metabolic process	IMP	J:207076