Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables DNA-binding transcription factor activity, RNA polymerase II-specific and transcription coactivator binding activity. Involved in several processes, including Peyer's patch development; negative regulation of thymocyte apoptotic process; and regulation of gene expression. Acts upstream of or within T cell differentiation; hematopoietic or lymphoid organ development; and regulation of gamma-delta T cell differentiation. Located in external side of plasma membrane and nucleus. Is expressed in several structures, including central nervous system; genitourinary system; gut; hemolymphoid system; and sensory organ. Human ortholog(s) of this gene implicated in immunodeficiency 42. Orthologous to human RORC (RAR related orphan receptor C).