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Psd4 Gene Detail
Summary
  • Symbol
    Psd4
  • Name
    pleckstrin and Sec7 domain containing 4
  • Synonyms
    EFA6B, SEC7 homolog
  • Feature Type
    protein coding gene
  • IDs
    MGI:2674093
    NCBI Gene: 215632
  • Alliance
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:24257571-24299882 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 16.38 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1308 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2674093
protein coding gene Chr2:24257571-24304966 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025409
protein coding gene Chr2:22172166-22221617 (+)
A/J MGP_AJ_G0025386
protein coding gene Chr2:21314043-21362303 (+)
AKR/J MGP_AKRJ_G0025356
protein coding gene Chr2:22045581-22094242 (+)
BALB/cJ MGP_BALBcJ_G0025382
protein coding gene Chr2:21422256-21471604 (+)
C3H/HeJ MGP_C3HHeJ_G0025143
protein coding gene Chr2:21980691-22028067 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025826
protein coding gene Chr2:22878619-22927061 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023237
protein coding gene Chr2:20241682-20289166 (+)
CAST/EiJ MGP_CASTEiJ_G0024606
protein coding gene Chr2:21815050-21865478 (+)
CBA/J MGP_CBAJ_G0025121
protein coding gene Chr2:23683838-23732230 (+)
DBA/2J MGP_DBA2J_G0025254
protein coding gene Chr2:21171607-21220762 (+)
FVB/NJ MGP_FVBNJ_G0025216
protein coding gene Chr2:20911504-20961492 (+)
LP/J MGP_LPJ_G0025340
protein coding gene Chr2:22103589-22158150 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025247
protein coding gene Chr2:23921151-23970888 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025885
protein coding gene Chr2:21972283-22024391 (+)
PWK/PhJ MGP_PWKPhJ_G0024354
protein coding gene Chr2:20956644-21003369 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024154
protein coding gene Chr2:22094839-22143128 (+)
WSB/EiJ MGP_WSBEiJ_G0024675
protein coding gene Chr2:22043058-22091504 (+)



Homology
more
  • Human Ortholog
    PSD4, pleckstrin and Sec7 domain containing 4
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PSD4, pleckstrin and Sec7 domain containing 4
  • Synonyms
    EFA6B, TIC
  • Links
    NCBI Gene ID: 23550
    neXtProt AC: NX_Q8NDX1
    UniProt: Q8NDX1

  • Chr Location
    2q14.1; chr2:113157325-113209396 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 215632 NCBI Gene Model | MGI Sequence Detail 42312 C57BL/6J ±  kb
transcript NM_001355231 RefSeq | MGI Sequence Detail 5428 C57BL/6  
polypeptide Q8BLR5 UniProt | EBI | MGI Sequence Detail 1005 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 14
    Primer pair 1

    Microarray probesets 5
References
more
  • Summaries
    All 36
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/01/2024
MGI 6.24
The Jackson Laboratory